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Child's Nervous System

, Volume 33, Issue 8, pp 1233–1236 | Cite as

George J. Garceau (1896–1977) and the first introduction of the “filum terminale syndrome”

  • Erfanul Saker
  • Marcus Cox
  • Marios Loukas
  • Rod J. Oskouian
  • R. Shane Tubbs
Cover Editorial

Introduction

The filum terminale syndrome is associated with spinal cord tethering and an abnormally positioned conus medullaris below L2–3 and often results in symptoms of a tethered cord [12]. This syndrome was first noticed and documented in the nineteenth century when the neurological, urological, and orthopedic manifestations associated with spina bifida occulta (SBO) were referred to as occult spinal dysraphism [8]. In 1910, Fuchs [1] speculated that incontinence seen in myelomeningocele patients during spinal flexion was due to increased tension on the distal spinal cord [6]. By 1940, Lichtenstein [7] furthered the concept of cord dysfunction secondary to tethering lesions [6]. However, it was not until 1953 when George J. Garceau (Fig. 1) [3] described the “filum terminale syndrome” (Fig. 2) hypothesizing that tension from an abnormally thickened filum terminale was responsible for spinal cord traction symptoms [6].
Fig. 1

Photograph of George Joseph Garceau

Fig. 2

Cover page of Garceau’s original “The film terminale syndrome (the cord-traction syndrome)” paper

Garceau was an orthopedic surgeon whose initial interest began with children and extended eventually to the care of patients of all ages. He was credited with contributing many original, innovative surgical insights and approaches to his field, particularly in such defects and diseases as club foot, congenital dislocation of the hip, Perthes disease, slipped epiphysis of adolescence, scoliosis, paralytic results of poliomyelitis and cerebral palsy, bone tumors, and degenerative joint disease [13].

Early life

George Joseph Garceau was born on May 24, 1896, in Centerville, Minnesota, USA. A practicing Roman Catholic, he was the son of Joseph Samuel, a mining engineer and a maker of machinery, and Mary (Pelletier) Garceau [13]. He received his elementary education at public schools in White Bear Lake, Minnesota. Garceau attended the University of Minnesota where his undergraduate studies were put on hold by his voluntary enlistment in the Marines. From 1917 to 1919, he served as a sergeant major in the US Marine Corps and with the 2nd Marine Division in World War I [10, 13]. He received military decoration for wounds received during his participation in the Battle of Belleau Wood (June 1–26, 1918) near the Marne River in France. He continued earning merits on his return to the university, receiving scholastic cognizance as well as varsity prominence on the football field, ice-hockey rink, and a boxing champion in the Marine Corps [10, 13]. Following completion of his undergraduate studies and receiving his bachelor of science degree in 1921, Garceau advanced his education by attending medical school at Northwestern University [10]. He was married in Indianapolis on June 2, 1927, to Julia May Davidson and had two daughters: Mary Dolores and Diana Ruth [13].

Early career

In 1925, Garceau received his doctor of medicine degree following completion of an internship at the Indianapolis Methodist Episcopal Hospital, Indianapolis, Indiana, USA. He completed his residency at St. Francis Hospital, Miami Beach, Florida, USA, in 1926–1927 and at Shriners’ Hospital for Crippled Children, Chicago, Illinois, USA, in 1927–1928 [13]. His postgraduate training also included house-officer positions in Boston and a return to Indianapolis [10]. From 1928 to 1933, Garceau was a surgery resident at Indiana University Hospital and was appointed the first chief of orthopedic surgery at the James Whitcomb Riley Hospital for Children [13].

From early on in his career, Garceau began training orthopedic residents and conducted formal classes in anatomy, pathology, and physiology. He developed a residency-rotation/training program that encompassed six hospitals, including Marion County General, Veterans Administration, Methodist Episcopal, and St. Vincent’s hospitals in Indianapolis. His purpose was so that residents would have the greatest possible contact with the private sector before they joined the professional ranks [10, 13]. Those fortunate to work with and be mentored by Garceau raved about the invigorating experience to observe his examination, evaluation, and approach to a problem. “As a teacher, his clarity and emphasis on priority and perspective were outstanding. As a surgeon, his insight and approaches were original, innovative, and ingenious, yet he never endangered life or limb. As a clinician-reporter, his absolute integrity can never be forgotten” [10].

Contributions to medicine and the tight filum terminale syndrome

In 1940, Garceau [2] first described transposition of the tibialis anterior tendon in recurrent congenital clubfoot and published his findings in the Journal of Bone and Joint Surgery [2, 5]. Based on these trials, he reported 77 % good and excellent results in forefoot adduction correction, and 93 % in inversion deformity correction [5]. The clinical appearance of feet was classified according to criteria established by Garceau based on observations he made on residual metatarsus adductus, heel varus, and equinus and offers a morphologic way of evaluating clinical results [5]. Since then, the tibialis anterior tendon transfer has been used widely in management of residual clubfoot deformity [5].

In 1953, Garceau observed improvement of progressive spastic paralysis following exploratory laminectomy and resection (performed during 1949–1951) of a thick, tight filum terminale in three patients [3, 9]. Prior to the discoveries made in the filum, these patients were initially being observed for other anomalies including congenital and idiopathic scoliosis, and tuberculosis of the spine [3]. In the patient with congenital scoliosis, it was noted that the conus medullaris retained its fetal position resulting in paralysis during the period of rapid growth. In the patient with idiopathic thoracolumbar scoliosis, the tightness of the filum was identified after observing a one-centimeter separation upon sectioning. The third patient experienced signs and symptoms of paraplegia during the period of rapid growth, which improved following sectioning of the filum terminale. Garceau hypothesized that the tension from a tight filum terminale may cause spinal cord symptomatology such as compression over an angulated spine or cord traction resulting in pulling of the hindbrain into the foramen magnum, i.e., Chiari malformation [3, 6]. He published (Fig. 2) his findings in the Journal of Bone and Joint Surgery [3] and acknowledged Dr. Robert F. Heimburger, then Associate Professor of Surgery at Indiana University for his contribution to the study. Based on his findings, Garceau was credited as the first physician to attribute neurological sequelae to a taut filum terminale [9, 11].

Garceau contributed many other papers to the medical literature. Among the other noteworthy were “Transplantation of the Iliacus Muscle for Loss of Hip Abductor Power,” “Solitary Unicameral Bone Cyst,” “A Preliminary Study of Selective Plantar-muscle Denervation for Pes Cavus,” and “Congenital Talipes Equinovarus” [13].

Accomplishments/legacy

Garceau was honored with many citations for his contributions to medicine, and in 1945, some of the residents under his tutelage organized the Riley Hospital Orthopedic Alumni Association in his honor. This organization continues to be active today and holds an annual fall lecture series known as the Garceau Lectures [4, 10, 13]. These lectures invite leading orthopedic surgery experts to present and discuss the most recent advances in the field of orthopedic surgery.

In 1948, Garceau was appointed Professor and Chairman of the newly established Department of Orthopedic Surgery at Indiana University School of Medicine. In the same year, he served as President of the Clinical Orthopedic Society. His contributions as a member and as President of the American Board of Orthopedic Surgery in 1957 provided excellence and advances in orthopedic educational standards. In 1960, he was appointed Vice President of the American Academy of Orthopedic Surgeons [10]. Garceau guided the Department of Orthopedic Surgery at Indiana for nearly 20 years until his retirement in 1966. In 1967, he was named Distinguished Professor Emeritus [10].

Death

Garceau ran a private practice in St. Vincent Indianapolis Hospital, where he was Chief of Orthopedic Services for 25 years, and one-time President of the Staff Society. He continued active teaching of residents and served on the hospital’s Research and Development Committee until his death on November 5, 1977 after a prolonged illness [10]. In 1974, the library of St. Vincent’s Hospital was dedicated in his name [13]. “The full impact of George Garceau’s influence is difficult to assess, but it is deeply appreciated by all who have known him and benefited by his noble example” [10].

Notes

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest.

References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Department of Anatomical SciencesSt. George’s UniversityGrenadaGrenada
  2. 2.Seattle Science FoundationSeattleUSA

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