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Child's Nervous System

, Volume 32, Issue 7, pp 1183–1185 | Cite as

Revisiting the metastatic potential of childhood pineal parenchymal tumor of intermediate differentiation: a case report

  • Navneet Singla
  • Ankur Kapoor
  • Sivashanmugam Dhandapani
  • B. D. Radotra
  • Debajyoti Chatterjee
Letter to the Editor

Dear Editor:

Pineal parenchymal tumor of intermediate differentiation (PPTID) is a rare entity, the biological behavior of which is largely unknown due to few reported cases overall and diagnostic pitfalls in the small sample [1, 2]. The extent of surgery as well as the role of adjuvant chemoradiotherapy in PPTID is still contentious. Dissemination into spinal axis, a known phenomenon for childhood pineoblastoma (PB), has been reported rarely in PPTID [2, 3, 4] and embarks upon redefining the treatment paradigms for these tumors. Simultaneous intracranial as well as spinal dissemination at presentation in childhood PPTID is a rarity indeed and provides new insights to the varied biology of this potentially malignant tumor.

A 10-year-old male presented with history of headache and gait disturbance for 2 months. Examination revealed papilloedema, upgaze palsy, gait ataxia and spasticity in both lower limbs. Magnetic resonance imaging revealed a well defined lesion at pineal region that...

Keywords

Label Index Ki67 Label Index Spinal Axis Spinal Dissemination Pineal Region 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Navneet Singla
    • 1
  • Ankur Kapoor
    • 1
  • Sivashanmugam Dhandapani
    • 1
  • B. D. Radotra
    • 2
  • Debajyoti Chatterjee
    • 2
  1. 1.Department of NeurosurgeryPGIMER ChandigarhChandigarhIndia
  2. 2.Department of HistopathologyPGIMER ChandigarhChandigarhIndia

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