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Child's Nervous System

, Volume 31, Issue 7, pp 1189–1193 | Cite as

Atypical extraventricular neurocytoma in a 3-year-old girl: case report with radiological-pathological correlation

  • Hiroo Kawano
  • Tokuhiro KimuraEmail author
  • Koji Iwata
  • Matakazu Furukawa
  • Sadahiro Nomura
  • Aya Ishii
  • Shinsuke Tanaka
  • Yoshinobu Hoshii
  • Michiyasu Suzuki
  • Eiji Ikeda
Case Report

Abstract

Background

Extraventricular neurocytoma (EVN) is a rare neuronal tumor histologically similar to central neurocytoma but arising in the brain parenchyma outside the ventricles. The minority of EVNs show atypical features including increased proliferative index, microvascular proliferation, or necrosis, and are called atypical EVN. Most of atypical EVNs occur in adults, and the tumors in children are extremely rare. A radiological-pathological correlation and radiological clue to atypical EVNs have not been clarified.

Case report

We report a case of atypical EVN in a 3-year-old girl. Magnetic resonance imaging (MRI) revealed an extraventricular intraparenchymal tumor in the left frontal lobe, which was composed of homogeneous well-demarcated cystic component and peripheral ill-delineated solid component with enhancement. Angiography demonstrated vascular proliferation and arteriovenous shunting in the tumor. Histologically, the resected tumor was diagnosed as atypical EVN. Types of the tumor borders (well-circumscribed or infiltrative) and MRI findings correlated closely. Morphology of the tumor vasculature was remarkable for microvascular proliferation and dilated, thickened veins, which corresponded to the angiographic features.

Conclusion

Although rare, atypical EVN should be included in the differential diagnosis of a cystic mass in the cerebral hemispheres in children. Radiological evaluation of tumor borders and angiographic characteristics might be useful for predicting atypicality of the tumor.

Keywords

Extraventricular neurocytoma Child Neuroimaging Angiography Histology Radiological-pathological correlation 

Notes

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Hiroo Kawano
    • 1
  • Tokuhiro Kimura
    • 2
    Email author
  • Koji Iwata
    • 3
  • Matakazu Furukawa
    • 4
  • Sadahiro Nomura
    • 5
  • Aya Ishii
    • 2
  • Shinsuke Tanaka
    • 6
  • Yoshinobu Hoshii
    • 6
  • Michiyasu Suzuki
    • 5
  • Eiji Ikeda
    • 2
  1. 1.Department of Basic Laboratory SciencesYamaguchi University Graduate School of MedicineUbeJapan
  2. 2.Department of PathologyYamaguchi University Graduate School of MedicineUbeJapan
  3. 3.Yamaguchi University HospitalUbeJapan
  4. 4.Department of RadiologyYamaguchi University Graduate School of MedicineUbeJapan
  5. 5.Department of NeurosurgeryYamaguchi University Graduate School of MedicineUbeJapan
  6. 6.Division of Surgical PathologyYamaguchi University HospitalUbeJapan

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