Child's Nervous System

, Volume 30, Issue 9, pp 1485–1492 | Cite as

Gamma Knife radiosurgery for arteriovenous malformations in pediatric patients

  • Alp Özgün Börcek
  • Hakan Emmez
  • Koray M. Akkan
  • Özgür Öcal
  • Gökhan Kurt
  • Şükrü Aykol
  • Eray Karahacioğli
  • Kemali M. Baykaner
Original Paper

Abstract

Objective

The authors present the results of Gamma Knife stereotactic radiosurgery performed in a series of children with arteriovenous malformations (AVMs).

Methods

Between June 2005 and January 2014, 75 patients 18 years old or younger received Gamma Knife radiosurgery for AVMs. Of these, 58 patients were eligible for further analysis. The median age of the population was 12 years; 41 % presented with hemorrhage, 34 % with neurological insult, and 24 % patients were diagnosed incidentally. The median AVM volume was 3.5 cm3. The median radiosurgery-based AVM score (RSBAVMS) was 0.86. The median follow-up period was 32 months.

Results

Single session Gamma Knife radiosurgery resulted in complete AVM obliteration in 40 (68.9 %) patients. There were 35 (60.3 %) excellent outcome (complete obliteration with no new deficits) in this series. During the follow-up period, nine (15.51 %) patients experienced new deficits and three (5.1 %) patients experienced intracranial hemorrhage. The annual rate of developing new deficits and hemorrhage was calculated as 5.45 and 1.8 %, respectively. Volume, gender, RSBAVMS, and nidus type factor were factors associated with excellent outcome.

Conclusions

Radiosurgery was successful in majority of patients with minimal morbidity. Gamma Knife radiosurgery for AVMs can be a safe and successful method in pediatric patients.

Keywords

AVM Gamma knife Pediatric neurosurgery Stereotactic radiosurgery 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Alp Özgün Börcek
    • 1
  • Hakan Emmez
    • 1
  • Koray M. Akkan
    • 2
  • Özgür Öcal
    • 1
  • Gökhan Kurt
    • 1
  • Şükrü Aykol
    • 1
  • Eray Karahacioğli
    • 3
  • Kemali M. Baykaner
    • 1
  1. 1.Department of Neurosurgery, Division of Pediatric Neurosurgery, Faculty of MedicineGazi UniversityAnkaraTurkey
  2. 2.Department of Radiology, Faculty of MedicineGazi UniversityAnkaraTurkey
  3. 3.Department of Radiation Oncology, Faculty of MedicineGazi UniversityAnkaraTurkey

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