Double neural tube defect: a case report and discussions on neural tube development
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Double neural tube defect is a rare congenital problem. A case illustration and current literatures on neural tube closure theory are discussed. The available theories are summarised and compared with regard to the case report.
A preterm baby with a parietal encephalocele and thoracic myelomeningocele is reported and management described. A two-staged surgery was performed.
The present case, the first described in Southeast Asia, appears to support a multi-site closure theory.
KeywordsSpinal dysraphism Neurulation Multi-site closure theory Encephalocele Myelomeningocele
- 3.Albright AL, Pollack IF, Adelson PD (1999) Principles and practice of pediatric neurosurgery. Thieme, StuttgartGoogle Scholar
- 8.Heuser CH, Streeter GL (1941) Development of the macvaque embryo Carnegie Inst Wash Publ 525. Contribs Embryo 29:15–55. Reprinted in Embryology of the Rhesus Monkey (macaca mulatta).Carnegie Inst Wasg Embryology Reprint, Volume 1Google Scholar
- 9.Mealey J Jr, Dzenitis AJ, Hockey AA (1970) Prognosis of encephalocoeles. J Neurosurg 2:209–218Google Scholar
- 10.Lorber J (1967) The prognosis of cephalocoeles. Deb Med Child Neurol Suppl 13:75–78Google Scholar
- 14.Sulik KK, Zuker RM, Dehart DB et al (1998) Normal patterns of neural tube closure differ in the human and mouse. Proc Greenwood Genetic Centre 18:129–130Google Scholar