Child's Nervous System

, Volume 24, Issue 3, pp 379–384 | Cite as

Papillary tumor of the pineal region in a child: case report and review of the literature

  • Kévin Buffenoir
  • Philippe Rigoard
  • Michel Wager
  • Sarah Ferrand
  • Alix Coulon
  • Jean Luc Blanc
  • Benoit Bataille
  • Antoine Listrat
Case Report
First Online:
Received:

Abstract

Case report

A 13-year-old boy presented with a history of intracranial hypertension. Radiologic studies revealed triventricular hydrocephalus secondary to a space-occupying lesion in the pineal region. Endoscopic third ventriculostomy was performed to treat hydrocephalus, and the lesion was biopsied. Complete resection of the tumor was subsequently performed. After a period of uncertainty, the diagnosis of papillary tumor of the pineal region was established. Tumor bed radiotherapy at a dose of 50 Gy was associated. With a follow-up of 15 months, the postoperative course was satisfactory with return to school and no residual tumor on magnetic resonance imaging.

Conclusion

Papillary tumors of the pineal region constitute a rare entity, with a difficult diagnosis, an uncertain prognosis, and a high risk of local recurrence; they must be treated by a combination of surgery and radiotherapy. The only identified prognostic factor is the complete or incomplete nature of surgical resection.

Keywords

Papillary tumor of the pineal region Pineal tumor Pediatric neurosurgery 
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Drummond KJ, Rosenfeld JV (1999) Pineal region tumours in childhood. A 30-year experience. Child’s Nerv Syst 15:119–126CrossRefGoogle Scholar
  2. 2.
    Fevre-Montagne M, Hasselblatt M, Figarella-Branger D, Chauveinc L, Champier J, Saint-Pierre G, Taillandier L, Coulon A, Paulus W, Fauchon F, Jouvet A (2006) Prognosis and histopathologic features in papillary tumors of the pineal region: a retrospective multicenter study of 31 cases. J Neuropathol Exp Neurol 65:1004–1011CrossRefGoogle Scholar
  3. 3.
    Hirato J, Nakazato Y (2001) Pathology of pineal region tumors. J Neurooncol 54:239–249PubMedCrossRefGoogle Scholar
  4. 4.
    Hasselblatt M, Blumcke I, Jeibmann A, Rickert CH, Jouvet A, van de Nes JA, Kuchelmeister K, Brunn A, Fevre-Montange M, Paulus W (2006) Immunohistochemical profile and chromosomal imbalances in papillary tumours of the pineal region. Neuropathol Appl Neurobiol 32:278–283PubMedCrossRefGoogle Scholar
  5. 5.
    Jouvet A, Fauchon F, Liberski P, Saint-Pierre G, Didier-Bazes M, Heitzmann A, Delisle MB, Biassette HA, Vincent S, Mikol J, Streichenberger N, Ahboucha S, Brisson C, Belin MF, Fevre-Montange M (2003) Papillary tumor of the pineal region. Am J Surg Pathol 27:505–512PubMedCrossRefGoogle Scholar
  6. 6.
    Kern M, Robbins P, Lee G, Watson P (2006) Papillary tumor of the pineal region—a new pathological entity. Clin Neuropathol 25:185–192PubMedGoogle Scholar
  7. 7.
    Kuchelmeister K, Hugens-Penzel M, Jodicke A, Schachenmayr W (2006) Papillary tumour of the pineal region: histodiagnostic consideration. Neuropathol Appl Neurobiol 32:203–208PubMedCrossRefGoogle Scholar
  8. 8.
    Park SH, Park HR, Chi JG (1996) Papillary Ependymoma: its differential diagnosis from choroids plexus papilloma. J Korean Medical Sci 11:415–421Google Scholar
  9. 9.
    Shibahara J, Todo T, Morita A, Mori H, Aoki S, Fukayama M (2004) Papillary neuroepithelial tumor of the pineal region. A case report. Acta Neuropathol 108:337–340PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Kévin Buffenoir
    • 1
    • 3
  • Philippe Rigoard
    • 1
  • Michel Wager
    • 1
  • Sarah Ferrand
    • 1
  • Alix Coulon
    • 2
  • Jean Luc Blanc
    • 1
  • Benoit Bataille
    • 1
  • Antoine Listrat
    • 1
  1. 1.Service de NeurochirurgieCHU de PoitiersPoitiersFrance
  2. 2.Service d’Anatomie PathologiqueCHU de PoitiersPoitiersFrance
  3. 3.Service de NeurochirurgieCHU de la MilétriePoitiersFrance

Personalised recommendations