Child's Nervous System

, Volume 22, Issue 8, pp 967–981

Peri-insular hemispherotomy in paediatric epilepsy

Special Annual Issue

DOI: 10.1007/s00381-006-0134-3

Cite this article as:
Villemure, JG. & Daniel, R.T. Childs Nerv Syst (2006) 22: 967. doi:10.1007/s00381-006-0134-3



Outline the indications, investigation, surgical technique, pitfalls, complications and benefits of peri-insular hemispherotomy (PIH) in the surgical treatment of paediatric epilepsy.

Materials and methods

This report is based on a consecutive series of 43 children who underwent PIH. Sixty percent were males; there were slightly more left-sided surgeries. Median interval between seizure onset and surgery was 5 years. In more than half the cases, the anatomical substrate was congenital. There were few complications: one death, one hydrocephalus and two anatomically remote haemorrhages. Ninety percent of the patients have remained in Engel’s class I epilepsy outcome.


There are clear indications for hemispherectomy in children. In some instances of incomplete deficit, timing of surgery remains a major concern. The less invasive approach to eliminate the influence of the diseased hemisphere, in our opinion, is with disconnective techniques of hemispherectomy, and among the latter, peri-insular hemispherotomy provides, in our opinion, the best complications–benefits ratio.


Peir-insular Hemispherotomy Epilepsy surgery Hemispherectomy 

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Neurosurgery ServiceCentre Hospitalier Universitaire VaudoisLausanneSwitzerland
  2. 2.Neurosurgery ServiceChristian Medical CollegeVelloreIndia

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