Child's Nervous System

, Volume 21, Issue 8–9, pp 622–627 | Cite as

The pathogenesis of craniopharyngiomas

  • Vikram C. PrabhuEmail author
  • Henry G. Brown
Special Annual Issue



The objective of the study is to review the pathogenesis of craniopharyngiomas.


A literature review of articles relating to the embryogenesis of the pituitary gland and sella and the pathogenesis of craniopharyngiomas was performed.


Craniopharyngiomas are benign, epithelial neoplasms of the sella and parasellar region seen in children and adults that may arise from neoplastic transformation of ectoderm-derived epithelial cell remnants of Rathke’s pouch and the craniopharyngeal duct.


Pathogenesis Craniopharyngioma Rathke’s pouch 



The authors thank John Shea, M.D., for reviewing the manuscript.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of NeurosurgeryLoyola University Medical CenterMaywoodUSA
  2. 2.Department of PathologyLoyola University Medical CenterMaywoodUSA

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