Heart and Vessels

, Volume 32, Issue 10, pp 1214–1219 | Cite as

Comparison of echocardiographic parameters to assess right ventricular function in pulmonary hypertension

  • Hirohisa Amano
  • Shichiro AbeEmail author
  • Suguru Hirose
  • Ryutaro Waku
  • Taiki Masuyama
  • Masashi Sakuma
  • Shigeru Toyoda
  • Isao Taguchi
  • Teruo Inoue
  • Chuwa Tei
Original Article


Although measurement of right ventricular ejection fraction (RVEF) may be relevant for evaluation of therapeutic efficacy and/or prognosis in patients with pulmonary hypertension, RVEF obtained by echocardiography has limited accuracy. In contrast, radionuclide and/or magnetic resonance imaging can measure RVEF more reliably. In this study, we investigated the relationship between RVEF measured by radionuclide angiography and the echocardiographic parameters that are recommended by the American Society of Echocardiography as representative of right heart function. There were 23 study participants with pulmonary hypertension who underwent radionuclide angiography and 2-dimensional and Doppler echocardiography (n = 30 measurements). RVEF measured by radionuclide angiography correlated with right ventricular Tei index (RV Tei index) measured by Doppler echocardiography (r = −0.601, P < 0.0005). Receiver operating characteristic curve analysis showed that an RV Tei index cut-off value of 0.371 was the best of predictor of RVEF ≤35% (area under the curve = 0.768, sensitivity = 0.857, selectivity = 0.667). Multiple regression analysis showed that RVEF was correlated with the RV Tei index, and this association was independent of other echocardiographic right ventricular function parameters (r = −0.644, P < 0.005). The RV Tei index measured by Doppler echocardiography may be an acceptable surrogate marker of RVEF in patients with pulmonary hypertension.


Echocardiography Pulmonary hypertension Radionuclide angiography Right ventricular ejection fraction Right ventricular Tei index 


Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to disclose.


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Copyright information

© Springer Japan 2017

Authors and Affiliations

  • Hirohisa Amano
    • 1
  • Shichiro Abe
    • 1
    Email author
  • Suguru Hirose
    • 1
  • Ryutaro Waku
    • 1
  • Taiki Masuyama
    • 1
  • Masashi Sakuma
    • 1
  • Shigeru Toyoda
    • 1
  • Isao Taguchi
    • 2
  • Teruo Inoue
    • 1
  • Chuwa Tei
    • 1
    • 3
  1. 1.The Department of Cardiovascular MedicineDokkyo Medical University School of MedicineMibuJapan
  2. 2.The Department of Cardiology, Koshigaya HospitalDokkyo Medical University School of MedicineKoshigayaJapan
  3. 3.Waon Therapy Research InstituteTokyoJapan

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