Heart and Vessels

, Volume 21, Issue 4, pp 263–266

Churg–Strauss syndrome and congenital factor Leiden thrombophilia as nontypical causes of intracardiac thrombosis

  • Katarzyna Mizia-Stec
  • Zbigniew Gąsior
  • Jan Duława
  • Mirosława Janowska
  • Piotr Pysz
  • Magdalena Mizia
CASE REPORT

DOI: 10.1007/s00380-005-0880-2

Cite this article as:
Mizia-Stec, K., Gąsior, Z., Duława, J. et al. Heart Vessels (2006) 21: 263. doi:10.1007/s00380-005-0880-2

Abstract

We present and discuss the case of a 26-year-old man suffering from Churg–Strauss syndrome (CSS). In our patient the disease severely affected both the heart and the lungs. Left ventricular dysfunction and intracardiac thrombosis, probably secondary to the cardiotoxic effect of eosinophils, were revealed by echocardiography. The risk of thrombosis was additionally increased by the coexistence of the factor V Leiden gene mutation. An opportunely established diagnosis allowed institution of an appropriate pharmacotherapy and subsequently to obtain a significant abatement of the clinical symptoms as well as the laboratory manifestations of the disease.

Key words

Churg–Strauss syndrome Intracardiac thrombosis Factor V Leiden gene mutation Genetics Thromboembolism 

Copyright information

© Springer-Verlag Tokyo 2006

Authors and Affiliations

  • Katarzyna Mizia-Stec
    • 1
  • Zbigniew Gąsior
    • 1
  • Jan Duława
    • 2
  • Mirosława Janowska
    • 2
  • Piotr Pysz
    • 1
  • Magdalena Mizia
    • 1
  1. 1.Department of CardiologySilesian University, Faculty of MedicineKatowicePoland
  2. 2.Department of Internal and Metabolic DisordersSilesian University School of MedicineKatowicePoland

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