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Journal of Comparative Physiology B

, Volume 185, Issue 1, pp 17–35 | Cite as

Trypsin isozymes in the lobster Panulirus argus (Latreille, 1804): from molecules to physiology

  • Erick Perera
  • Leandro Rodríguez-Viera
  • Rolando Perdomo-Morales
  • Vivian Montero-Alejo
  • Francisco Javier Moyano
  • Gonzalo Martínez-Rodríguez
  • Juan Miguel Mancera
Review

Abstract

Trypsin enzymes have been studied in a wide variety of animal taxa due to their central role in protein digestion as well as in other important physiological and biotechnological processes. Crustacean trypsins exhibit a high number of isoforms. However, while differences in properties of isoenzymes are known to play important roles in regulating different physiological processes, there is little information on this aspect for decapod trypsins. The aim of this review is to integrate recent findings at the molecular level on trypsin enzymes of the spiny lobster Panulirus argus, into higher levels of organization (biochemical, organism) and to interpret those findings in relation to the feeding ecology of these crustaceans. Trypsin in lobster is a polymorphic enzyme, showing isoforms that differ in their biochemical features and catalytic efficiencies. Molecular studies suggest that polymorphism in lobster trypsins may be non-neutral. Trypsin isoenzymes are differentially regulated by dietary proteins, and it seems that some isoenzymes have undergone adaptive evolution coupled with a divergence in expression rate to increase fitness. This review highlights important but poorly studied issues in crustaceans in general, such as the relation among trypsin polymorphism, phenotypic (digestive) flexibility, digestion efficiency, and feeding ecology.

Keywords

Digestion biochemistry Ecological physiology Panulirus argus Protein digestion Trypsin polymorphism Spiny lobster 

Notes

Acknowledgments

Most of the work outlined on this topic was supported by the International Foundation for Science (No. A/4306-1 and No. A/4306-2) granted to EP, the Agencia Española de Cooperación Internacional/Asociación Universitaria Iberoamericana de Postgrado (AUIP/AECI) from Spain, and the Program ʻDoctorado Iberoamericano en Ciencias’ at the University of Cadiz, Spain.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Erick Perera
    • 1
    • 4
  • Leandro Rodríguez-Viera
    • 1
  • Rolando Perdomo-Morales
    • 2
  • Vivian Montero-Alejo
    • 2
  • Francisco Javier Moyano
    • 3
  • Gonzalo Martínez-Rodríguez
    • 4
  • Juan Miguel Mancera
    • 5
  1. 1.Center for Marine ResearchUniversity of HavanaHavanaCuba
  2. 2.Biochemistry DepartmentCenter for Pharmaceuticals Research and DevelopmentHavanaCuba
  3. 3.Department of Applied BiologyUniversity of AlmeriaAlmeríaSpain
  4. 4.ICMAN-CSIC, Apartado OficialPuerto RealSpain
  5. 5.Department of Biology, Faculty of Marine and Environmental ScienceUniversity of CadizCádizSpain

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