Komplementfaktor H und die altersabhängige Makuladegeneration

Charbel Issa P, Scholl HPN, Holz FG, Oppermann M, Knolle P, Kurts C (2005) Das Komplementsystem und dessen mögliche Beteiligung an der Pathogenese der altersabhängigen Makuladegeneration (AMD). Ophthalmologe. DOI:  10.1007/s00347-005-1269-4

Daiger SP (2005) Genetics. Was the human genome project worth the effort? Science 308:362–364CrossRefPubMedGoogle Scholar

Edwards AO, Ritter R, Abel KJ, Manning A, Panhuysen C, Farrer LA (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308:421–424CrossRefPubMedGoogle Scholar

Hageman GS, Anderson DH, Johnson LV et al. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA 102:7227–7232CrossRefPubMedGoogle Scholar

Hageman GS, Luthert PJ, Chong NHV, Johnson LV, Anderson DH, Mullins RF (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch’s membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 20:705–732CrossRefPubMedGoogle Scholar

Haines JL, Hauser MA, Schmidt S et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308:419–421CrossRefPubMedGoogle Scholar

Klein RJ, Zeiss C, Chew EY et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308:385–389CrossRefPubMedGoogle Scholar

Scholl HPN, Weber BHF, Nöthen MM, Wienker T, Holz FG (2005) Y402H-Polymorphismus im Komplementfaktor H und altersabhängige Makuladegeneration (AMD). Ophthalmologe. DOI:  10.1007/s00347-005-1270-4