World Journal of Urology

, Volume 33, Issue 4, pp 555–562 | Cite as

Update on the use of diode laser in the management of benign prostate obstruction in 2014

  • Lukas Lusuardi
  • Michael Mitterberger
  • Stephan Hruby
  • Thomas Kunit
  • Birgit Kloss
  • Paul F. Engelhardt
  • Manuela Sieberer
  • Günter Janetschek
Topic Paper



To determine the status quo in respect of various diode lasers and present the techniques in use, their results and complications. We assess how these compare with transurethral resection of the prostate and other types of laser in randomized controlled trials (RCTs). When adequate RCTs were not available, case studies and reports were evaluated.

Materials and methods

Laser for the treatment of benign prostatic hyperplasia (BPH) has aroused the interest and curiosity of urologists as well as patients. The patient associates the term laser with a successful and modern procedure. The journey that started with coagulative necrosis of prostatic adenoma based on neodymium: yttrium–aluminum–garnet (Nd:YAG) laser has culminated in endoscopic “enucleation” with holmium laser. Diode laser is being used in urology for about 10 years now. Various techniques have been employed to relieve bladder outlet obstruction due to BPH.


The diode laser scenario is marked by a diversity of surgical techniques and wavelengths. We summarize the current published literature in respect of functional results and complications.


More randomized controlled studies are needed to determine the position and the ideal technique of diode laser treatment for BPH.


Benign prostatic hyperplasia Diode laser Vaporization Vaporesection Enucleation DiLEP 


Conflict of interest

The authors declare that they have no conflict of interest.

Ethical standard

All included human and animal studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1,964 Declaration of Helsinki and its later amendments.All persons gave their informed consent prior to their inclusion in the presented studies.Details that might disclose the identity of the subjects under study are omitted.The corresponding author takes on the above responsibilities.


  1. 1.
    Bachmann A, Woo HH, Wyler S et al (2012) Laser prostatectomy of lower urinary tract symptoms due to benign prostate enlargement: a critical review of evidence. Curr Opin Urol 22:22–33CrossRefPubMedGoogle Scholar
  2. 2.
    Bach T, Muschter R, Sroka R et al (2012) Laser treatment of benign prostatic obstruction: basics and physical differences. Eur Urol 61:317–325CrossRefPubMedGoogle Scholar
  3. 3.
    Rieken M, Bachmann A (2014) Laser treatment of benign prostate enlargement—which laser for which prostate? Nat Rev Urol 11:142–152CrossRefPubMedGoogle Scholar
  4. 4.
    Ruszat R, Seitz M, Wyler SF et al (2009) Prospective single-centre comparison of-W diode-pumped solid-state high-intensity system laser vaporization of the prostate and 200-W high-intensive diode-laser ablation of the prostate for treating benign prostatic hyperplasia. BJU Int 104:820–825CrossRefPubMedGoogle Scholar
  5. 5.
    Chiang PH, Chen CH, Kang CH et al (2010) Green Light HPS laser 120-W versus diode laser 200-W vaporization of the prostate: comparative clinical experience. Lasers Surg Med 42:624–629CrossRefPubMedGoogle Scholar
  6. 6.
    Erol A, Cam K, Tekin A et al (2009) High power diode laser vaporization of the prostate: preliminary results for benign prostatic hyperplasia. J Urol 182:1078–1082CrossRefPubMedGoogle Scholar
  7. 7.
    Yang KS, Seong YK, Kim IG et al (2011) Initial experiences with a 980 nm diode laser for photoselective vaporization of the prostate for the treatment of benign prostatic hyperplasia. Korean J Urol 52:752–756CrossRefPubMedCentralPubMedGoogle Scholar
  8. 8.
    Shaker HS, Shoeb MS, Yassin MM et al (2012) Quartz head contact laser fiber: a novel fiber for laser ablation of the prostate using the 980 nm high power diode laser. J Urol 187:575–579CrossRefPubMedGoogle Scholar
  9. 9.
    Lee WC, Lin YH, Hou CP et al (2013) Prostatectomy using different lasers for the treatment of benign prostate hyperplasia in aging males. Clin Interv Aging 8:1483–1488PubMedCentralPubMedGoogle Scholar
  10. 10.
    Kim Y, Seong YK, Kim IG et al (2013) Twelve-month follow-up results of photoselective vaporization of the prostate with a 980-nm diode laser for treatment of benign hyperplasia. Korean J Urol 54:677–681CrossRefPubMedCentralPubMedGoogle Scholar
  11. 11.
    Chen CH, Chiang PH, Lee WC et al (2012) High-intensity diode laser in combination with bipolar transurethral resection of the prostate: a new strategy for the treatment of large prostates (>80 ml). Lasers Surg Med 44:699–704CrossRefPubMedGoogle Scholar
  12. 12.
    Gilling PJ, Cass CB, Malcolm AR et al (1995) Combination holmium and Nd: YAG laser ablation of the prostate: initial clinical experience. J Endourol 9:151–153CrossRefPubMedGoogle Scholar
  13. 13.
    Shih HJ, Chen JT, Chen YL et al (2013) Laser-assisted bipolar transurethral resection of the prostate with the oyster procedure for patients with prostate glands larger than 80 ml. Urology 81:1315–1319CrossRefPubMedGoogle Scholar
  14. 14.
    Leonardi R, Caltabiano R, Lanzafame S et al (2010) Histological evaluation of prostatic tissue following transurethral laser resection (TULaR) using the 980 nm diode laser. Arch Ital Urol Androl 82:1–4PubMedGoogle Scholar
  15. 15.
    Buisan O, Saladie JM, Ruiz JM et al (2011) Enucleación prostática con láser de diodo (DiLEP): técnica y resultados iniciales. Actas Urol Esp 35:37–41CrossRefPubMedGoogle Scholar
  16. 16.
    Lusuardi L, Myatt A, Sieberer M et al (2011) Safety and efficacy of eraser laser enucleation of the prostate: preliminary report. J Urol 186:1967–1971CrossRefPubMedGoogle Scholar
  17. 17.
    Khoder WY, Sroka R, Hennig G et al (2011) The 1,318-nm diode laser supported partial nephrectomy in laparoscopic and open surgery: preliminary results of a prospective feasibility study. Lasers Med Sci 26:689–697CrossRefPubMedGoogle Scholar
  18. 18.
    Yang SS, Hsieh CH, Lee YS et al (2013) Diode laser (980 nm) enucleation of the prostate: a promising alternative to transurethral resection of the prostate. Lasers Med Sci 28:353–360CrossRefPubMedGoogle Scholar
  19. 19.
    Yang SS, Hsieh CH, Chiang IN et al (2013) Prostate volume did not affect voiding function improvements in diode laser enucleation of the prostate. J Urol 189:993–998CrossRefPubMedGoogle Scholar
  20. 20.
    Xu A, Zou Y, Li B et al (2013) A randomized trial comparing diode laser enucleation of the prostate with plasmakinetic enucleation and resection of the prostate for the treatment of benign prostatic hyperplasia. J Endourol 27:1254–1260CrossRefPubMedGoogle Scholar
  21. 21.
    Wendt-Nordahl G, Huckele S, Honeck P et al (2007) 980-nm Diode laser: a novel laser technology for vaporization of the prostate. Eur Urol 52:1723–1728CrossRefPubMedGoogle Scholar
  22. 22.
    Rieken M, Wyler S, Muller G et al (2009) Laser vaporization of the prostate: intermediate-term follow-up with the 200 W high-intensity diode (HiDi) laser system. Eur Urol Suppl 8(4):269 abstract #589Google Scholar
  23. 23.
    Chiang PH, Chen CH, Kang CH et al (2010) Green Light HPS laser 120-W versus diode laser 200-W vaporization of the prostate: comparative clinical experience. Lasers Surg Med 42:624–629CrossRefPubMedGoogle Scholar
  24. 24.
    Chen CH, Chiang PH, Chuang YC et al (2010) Preliminary results of prostate vaporization in the treatment of benign prostatic hyperplasia by using a 200-W high-intensity diode laser. Urology 75:658–663CrossRefPubMedGoogle Scholar
  25. 25.
    Seitz M, Sroka R, Gratzke C et al (2007) The diode laser: a novel side-firing approach for laser vaporization of the human prostate—immediate efficacy and 1-year follow-up. Eur Urol 52:1717–1722CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Lukas Lusuardi
    • 1
  • Michael Mitterberger
    • 1
  • Stephan Hruby
    • 1
  • Thomas Kunit
    • 1
  • Birgit Kloss
    • 1
  • Paul F. Engelhardt
    • 1
  • Manuela Sieberer
    • 1
  • Günter Janetschek
    • 1
  1. 1.Department of Urology and AndrologyParacelsus Medical University SalzburgSalzburgAustria

Personalised recommendations