World Journal of Urology

, Volume 31, Issue 3, pp 645–649 | Cite as

TVT versus TOT, 2-year prospective randomized study

Original Article
First Online:
Received:
Accepted:

Abstract

Purpose

To evaluate in a comprehensive way TVT in comparison with TOT, the results of a single-center RCT are presented. Many studies addressed efficacy and safety of TVT and TOT.

Methods

Women included were adults having predominant SUI with positive stress test. They were randomized to get either TVT (Gynecare®) or TOT (Aris®). All women were seen 1 week, 3, 6, 12, 18, and 24 months.

Results

Seventy-one women completed 2-year follow-up. Median age was 47 (range 33–60 years). Mean ± SD BMI in TVT group was 34 ± 5 while in TOT group was 32 ± 5 kg/m2. POP of any degree was seen in 50 % (35 women). At 1 year, pad test–negative women were 31 and 29 for TVT and TOT, respectively. At 2 years, figures became 28 in TVT group and 27 in TOT. At 1 year, UDI 6 and IIQ 7 decreased by 78.5 and 81 % for TVT and by 69 % and 75 % for TOT group. At 2 year, comparable percentages were 73 and 79 % for TVT and 69 and 82 % for TOT. Fifteen unique patients had adverse events, 10 of them had TOT.

Conclusions

Both tapes have similar efficacy, regarding cure of incontinence. TVT is more effective, albeit insignificantly, than TOT at 2 years. However, serious adverse events were more frequent with TVT, yet TOT has more unique adverse events.

Keywords

Outcome RCT TVT TOT 

Abbreviations

ICIQ-SF

International Consultation on Incontinence Questionnaire ShortForm

IIQ 7

Incontinence impact questionnaire 7 (Short form)

KHQ

King’s Health questionnaire

MUS

Midurethral sling

P det Q max

Detrusor pressure at maximum flow

POP

Pelvic organ prolapse

PVR

Postvoid residual urine

PVS

Pubovaginal sling

PGI-I

Patient global impression of improvement of incontinence

Q max

Maximum flow rate

RCT

Randomized controlled trial

SUI

Stress urinary incontinence

TVT

Tension-free vaginal tape

TOT

Transobturator tape

UDI 6

Urogenital distress inventory 6 (Short form)

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Notes

Conflict of interest

None.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Voiding Dysfunction and Incontinence Unit, Urology and Nephrology CenterMansoura UniversityMansouraEgypt
  2. 2.Voiding Dysfunction and Female Urology Unit, Urology and Nephrology CenterMansoura UniversityMansouraEgypt

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