World Journal of Urology

, Volume 22, Issue 3, pp 196–199 | Cite as

Linear growth after enterocystoplasty in children and adolescents: a review

  • Gerald Mingin
  • Paul Maroni
  • Elmar W. Gerharz
  • Christopher R. J. Woodhouse
  • Laurence S. Baskin
Topic Paper


The interposition of bowel in continuity with the urinary tract has allowed for the preservation of renal function and continence in children with bladder exstrophy, as well as neurogenic and valve bladders. Although bladder augmentation with ileum or colon has been shown to be safe, the long-term effects of metabolic acidosis in addition to abnormalities in linear growth and bone metabolism remain largely unknown. We reviewed the literature to critically examine linear growth in children who have had bladder augmentation with a particular emphasis on the correlation between acid-base status, bone mineralization and growth. The majority of studies suggest that linear growth is not affected by bladder augmentation. In the short-term, children post-augmentation have varying degrees of metabolic acidosis which, overtime, appears to resolve with no affect on linear growth. In a single study, bladder augmentation led to significant bone demineralization almost a decade after surgery, however, even in these children no decrease in linear growth was noted. No alterations in bone density levels were seen with short-term follow-up.


Linear growth Enterocystoplasty Urinary diversion 



The study by Mingin et al. 2002 [8] was supported by NIH M01 RR01271 from the UCSF Pediatric Clinical Research Center.


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Gerald Mingin
    • 1
  • Paul Maroni
    • 1
  • Elmar W. Gerharz
    • 2
  • Christopher R. J. Woodhouse
    • 3
  • Laurence S. Baskin
    • 4
  1. 1.Division of Pediatric Surgical ResearchDenver Children’s HospitalDenverUSA
  2. 2.Department of UrologyJulius-Maximilians-University Medical School
  3. 3.The Institute of Urology and NephrologyUniversity College London
  4. 4.Department of Pediatric UrologyUniversity of California

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