World Journal of Urology

, Volume 21, Issue 6, pp 382–391 | Cite as

Occupational exposure and urological cancer

  • Klaus Golka
  • Andreas Wiese
  • Giorgio Assennato
  • Hermann M. Bolt
Topic Paper

Abstract

Occupational exposure is definitely a major cause of cancer. In the field of urology, the urinary bladder is the most important target. A classical cause of bladder cancer is exposure to carcinogenic aromatic amines, especially benzidine and β-naphthylamine. Such exposures were related to work places in the chemical industry, implying production and processing of classical aromatic amines, and in the rubber industry. Occupational bladder cancer has also been observed in dyers, painters and hairdressers. Even some occupations with much lower exposures to carcinogenic aromatic amines, like coke oven workers or workers in the rubber industry after the ban on β-naphthylamine, are at risk. In these occupations, exposure to complex mixtures of substances containing combustion products (e.g. polycyclic aromatic hydrocarbons) or nitrosamines is common. Renal cell cancer has been observed as an occupational disease in cases of very high exposure to trichloroethylene having led to narcotic or prenarcotic symptoms. Occupationally related cancers of the prostate or the testes appear currently not relevant.

Keywords

Transitional cell carcinoma Renal cell carcinoma Occupational exposure Aromatic amines Combustion products 

References

  1. 1.
    Alavanja MC, Samanic C, Dosemeci M, Lubin J, Tarone R, Lynch CF et al (2003) Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort. Am J Epidemiol 157:800–814CrossRefPubMedGoogle Scholar
  2. 2.
    Anonymous (1979) Benzo(a)pyren am Arbeitsplatz. Staubforschungsinstitut und Institut für Lärmbekämpfung des Hauptverbandes der gewerblichen Berufsgenossenschaften eV, Bonn (STF/IFL Information Nr 8/79)Google Scholar
  3. 3.
    Anonymous (1983) Polyzyklische aromatische Kohlenwasserstoffe (PAH) am Arbeitsplatz. Berufsgenossenschaftliches Institut für Arbeitssicherheit, St Augustin (BIA-Report 3/83)Google Scholar
  4. 4.
    Anthony HM (1974) Industrial exposure in patients with carcinoma of the bladder. J Soc Occup Med 24:110–116Google Scholar
  5. 5.
    Axelson O, Seldén A, Andersson K, Hogstedt C (1994) Updated and expanded Swedish cohort study on trichloroethylene and cancer risk. J Occup Med 36:556–562PubMedGoogle Scholar
  6. 6.
    Baxter PJ, McDowall ME (1986) Occupation and cancer in London: an investigation into nasal and bladder cancer using the Cancer Atlas. Br J Ind Med 43:44–49PubMedGoogle Scholar
  7. 7.
    Bethwaite P, Pearce N, Fraser J (1990) Cancer risks in painters: study based on the New Zealand Cancer Registry. Br J Ind Med 47:742–746PubMedGoogle Scholar
  8. 8.
    Bi W, Hayes RB, Feng P, Qi Y, You X, Zhen J, et al (1992) Mortality and incidence of bladder cancer in benzidine-exposed workers in China. Am J Ind Med 21:481–489PubMedGoogle Scholar
  9. 9.
    Blair A, Zahm SH (1991) Cancer among farmers. Occup Med State of the Art Reviews 6:335–354Google Scholar
  10. 10.
    Blair A, Decoufle P, Grauman D (1979) Causes of death among laundry and dry cleaning workers. Am J Public Health 69:508–511PubMedGoogle Scholar
  11. 11.
    Blair A, Stewart PA, Tolbert PE, Grauman D, Moran FX, Vaught J, et al (1990) Cancer and other causes of death among a cohort of dry cleaners. Br J Ind Med 47:162–168PubMedGoogle Scholar
  12. 12.
    Blair A, Petralia SA, Stewart PA (2003) Extended mortality follow-up of a cohort of dry cleaners. Ann Epidemiol 13:50–56CrossRefPubMedGoogle Scholar
  13. 13.
    Bolm-Audorff U, Jöckel KH, Kilguss B, Pohlabeln H, Siepenkothen T (1993) Bösartige Tumoren der ableitenden Harnwege und Risiken am Arbeitsplatz. Wirtschaftsverlag NW, Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Dortmund, Forschung; Fb 697)Google Scholar
  14. 14.
    Bolt HM (1995) Special points in the toxicity assessment of colourants (dyes and pigments) In: Thomas H, Hess R, Waechter F (eds) Toxicology of industrial compounds. Taylor & Francis, London, pp 303–310Google Scholar
  15. 15.
    Bolt HM, Golka K (1993a) Zur früheren Exposition von Malern gegenüber Azofarbmitteln. Arbeitsmed Sozialmed Umweltmed 28:417–421Google Scholar
  16. 16.
    Bolt HM, Golka K (1993b) Cases of lung cancer and tar-related skin changes in an aluminium reduction plant. Med Lav 84:178–181PubMedGoogle Scholar
  17. 17.
    Brennan P, Bogillot O, Cordier S, Greiser E, Schill W, Vineis P, et al (2000) Cigarette smoking and bladder cancer in men: a pooled analysis of 11 case-control studies. Int J Cancer 86:289–294PubMedGoogle Scholar
  18. 18.
    Brown DP, Kaplan SD (1987) Retrospective cohort mortality study of dry cleaner workers using perchloroethylene. J Occup Med 29:535–541PubMedGoogle Scholar
  19. 19.
    Brüning T, Bolt HM (2000) Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies. Crit Rev Toxicol 2000 30:253–285Google Scholar
  20. 20.
    Brüning T, Chronz C, Thier R, Havelka J, Ko Y, Bolt HM (1999) Occurrence of urinary tract tumors in miners highly exposed to dinitrotoluene. J Occup Environ Med 41:144–149PubMedGoogle Scholar
  21. 21.
    Brüning T, Pesch B, Wiesenhütter B, Rabstein S, Lammert M, Baumüller A, et al (2003) Renal cell cancer risk and occupational exposure to trichloroethylene: results of a consecutive case-control study in Arnsberg, Germany. Am J Ind Med. 43:274–285Google Scholar
  22. 22.
    Case RAM, Hosker ME (1954) Tumours of the urinary bladder as an occupational disease in the rubber industry in England and Wales. Br J Prev Soc Med 8:39–50PubMedGoogle Scholar
  23. 23.
    Checkoway H, Smith A, McMichael A, Jones F, Monson R, Tyroler H (1981) A case-control study of bladder cancer in the United States rubber and tyre industry. Br J Ind Med 38:240–246PubMedGoogle Scholar
  24. 24.
    Chen R, Seaton A (1998) A meta-analysis of painting exposure and cancer mortality. Cancer Detect Prev 22:533–539CrossRefPubMedGoogle Scholar
  25. 25.
    Claude J, Kunze E, Frentzel-Beyme R (1988) Occupation and risk of cancer of the lower urinary tract among men: a case-control study. Int J Cancer 41:271–279Google Scholar
  26. 26.
    Clavel J, Mandereau L, Limasset JC, Hemond D, Cordier S (1994) Occupational exposure to polycyclic aromatic hydrocarbons and the risk of bladder cancer: a French case-control study. Int J Epidemiol 23:1145–1153Google Scholar
  27. 27.
    Coggon D, Pannett B, Acheson ED (1984) Use of job-exposure matrix in an occupational analysis of lung and bladder cancers on the basis of death certificates. J Natl Cancer Inst 72:61–65Google Scholar
  28. 28.
    Cordier S, Clavel J, Limasset JC, Boccon-Gibod L, Le Moual L, Mandereau L, et al (1993) Occupational risks of bladder cancer in France: a multicentre case-control study. Int J Epidemiol 22:403–411Google Scholar
  29. 29.
    Delzell E, Austin H, Cole P (1988) Epidemiologic studies of the petroleum industry. Occup Med State of the Art Reviews 3:455–474Google Scholar
  30. 30.
    Dewan A, Jani JP, Patel JS, Gandhi DN, Variya MR, Ghodasara NB (1988) Benzidine and its acetylated metabolites in the urine of workers exposed to Direkt Black 38. Arch Environ Health 43:269–272Google Scholar
  31. 31.
    DFG (1977) Phenyl-2-naphthylamin. In: Gesundheitschädliche Arbeitsstoffe. Toxikologisch-Arbeitsmedizinische Begründungen von MAK-Werten. Senatskommission zur Prüfung gesundheitschädlicher Arbeitstoffe. Greim H (Hrsg). Wiley-VCH, WeinheimGoogle Scholar
  32. 32.
    Doll R, Vessey MP, Beasley RWR, Buckley AR, Fear EC, Fisher REW, et al (1972) Mortality of gasworkers—final report of a prospective study. Br J Ind Med 29:394–406Google Scholar
  33. 33.
    Duh RW, Nabih RA (1984) Mortality among laundry and dry cleaning workers in Oklahoma. Am J Publ Health 74:1278–1280Google Scholar
  34. 34.
    Elinder CG, Kjellstrom T, Hogstedt C, Andersson K, Spang G (1985) Cancer mortality of cadmium workers. Br J Ind Med 42:651–655Google Scholar
  35. 35.
    Enterline PE, Hartley J, Henderson V (1987) Asbestos and cancer: a cohort followed up to death. Br J Ind Med 44:396–401Google Scholar
  36. 36.
    Evanoff BA, Gustavsson P, Hogstedt C (1993) Mortality and incidence of cancer in a cohort of Swedish chimney sweeps: an extended follow up study. Br J Ind Med 50:450–459Google Scholar
  37. 37.
    Frumin E, Velez H, Bingham E, Gillen M, Brathwaite M, LaBarck R (1990) Occupational bladder cancer in textile dyeing and printing workers: six cases and their significance for screening programs. J Occup Med 32:887–890PubMedGoogle Scholar
  38. 38.
    Gago-Dominguez M, Castelao JE, Yuan JM, Yu MC, Ross RK (2001) Use of permanent hair dyes and bladder-cancer risk. Int J Cancer 91:575–579CrossRefPubMedGoogle Scholar
  39. 39.
    Gago-Dominguez M, Bell DA, Watson MA, Yuan JM, Castelao JE, Hein DW, et al (2003) Permanent hair dyes and bladder cancer: risk modification by cytochrome P450 1A2 and N-acetyltransferases 1 and 2. Carcinogenesis 24:483–489CrossRefPubMedGoogle Scholar
  40. 40.
    Golka K (1999) Untersuchungen zur beruflichen Exposition bei Patienten mit Harnblasenkarzinom. Habilitationsschrift zur Erlangung der Venia legendi für das Fach “Arbeitsmedizin”. Medizinische Fakultät der Ruhr-Universität BochumGoogle Scholar
  41. 41.
    Golka K, Schöps W, Kierfeld G, Bolt HM (1994) Urothelial diseases as an occupational disease. Versicherungsmedizin 46:158–161 (in German)PubMedGoogle Scholar
  42. 42.
    Golka K, Prior V, Blaszkewicz M, Cascorbi I, Schöps W, Kierfeld G, et al (1996) Occupational history aspects and genetic N-acetyltransferase (NAT2) polymorphism in urothelial cancer patients in Leverkusen, Germany. Scand J Work Environ Health 22:332–338PubMedGoogle Scholar
  43. 43.
    Golka K, Reckwitz T, Kempkes M, Cascorbi I, Blaszkewicz M, Reich SE, et al (1997) N-Acetyltransferase 2 (NAT2) and glutathione S-transferase µ (GSTM1) in bladder cancer patients in a highly industrialized area. Int J Occup Environ Health 3:105–110PubMedGoogle Scholar
  44. 44.
    Golka K, Bandel T, Schlaefke S, Reich SE, Reckwitz T, Urfer W, et al (1998) Urothelial cancer of the bladder in an area of former coal, iron, and steel industries in Germany: a case-control study. Int J Occup Environ Health 4:79–84PubMedGoogle Scholar
  45. 45.
    Golka K, Bandel T, Reckwitz T, Urfer W, Bolt HM, Bremicker KD, et al (1999) Occupational risk factors for bladder carcinoma. A case control study. Urologe [A] 38:358–363 (in German)Google Scholar
  46. 46.
    Golka K, Prior V, Blaszkewicz M, Bolt HM (2002) The enhanced bladder cancer susceptibility of NAT2 slow acetylators towards aromatic amines: a review considering ethnic differences. Toxicol Lett 128:229–241CrossRefPubMedGoogle Scholar
  47. 47.
    Greiser E, Mohlzahn M (1997) Multizentrische Nieren- und Urothel-Carcinom-Studie Wirtschaftsverl NW, Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Dortmund/Berlin, Forschung; Fb 780)Google Scholar
  48. 48.
    Grimmer G, Naujack KW, Dettbarn G (1987) Beitrag zur Ursachenforschung exogen bedingter Blasencarcinome. Profilanalyse aromatischer Amine am Arbeitsplatz. Schriftenreihe der Bundesanstalt für Arbeitsschutz, Wirtschaftverlag NW, Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Dortmund, Forschung; Fb 511)Google Scholar
  49. 49.
    Guidotti TL (1993) Mortality of urban firefighters in Alberta, 1927–1987. Am J Ind Med 23:921–940PubMedGoogle Scholar
  50. 50.
    Gustavsson P, Gustavsson A, Hogstedt C (1988) Excess of cancer in Swedish chimney sweeps. Br J Ind Med 45:777–781PubMedGoogle Scholar
  51. 51.
    Hammond EC, Selikoff IJ, Lawther PL, Seidman H (1976) Inhalation of benzpyrene and cancer in man. Ann N Y Acad Sci 271:116–124PubMedGoogle Scholar
  52. 52.
    Hansen ES (1991) Cancer mortality among Danish molders. Am J Ind Med 20:401–409PubMedGoogle Scholar
  53. 53.
    Henschler D, Vamvakas S, Lammert M, Dekant W, Kraus B, Thomas MB, et al (1995) Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene. Arch Toxicol 69:291–299Google Scholar
  54. 54.
    Hueper WC, Wiley FH, Wolfe HD (1938) Experimental production of bladder tumors in dogs by administration of beta-naphthylamine. Ind Hyg Toxicol 20:46–84Google Scholar
  55. 55.
    IARC International Agency for Research on Cancer (1989) IARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans: Some organic solvents, resin monomers and related compounds, pigments, and occupational exposures in paint manufacture and painting. World Health Organization, Lyon (IARC monographs on the evaluation of carcinogenic risks to humans, vol. 47)Google Scholar
  56. 56.
    IARC International Agency for Research on Cancer (1993) IARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans: Occupational exposures of hairdressers and barbers and personal use of hair colourants, some hair dyes, cosmetic colourants, industrial dyestuffs and aromatic amines. World Health Organization, Lyon (IARC monographs on the evaluation of carcinogenic risks to humans, vol. 57)Google Scholar
  57. 57.
    Katz RM, Jowett D (1981) Female laundry and dry cleaning workers in Wisconsin: a mortality analysis. Am J Public Health 71:305–307PubMedGoogle Scholar
  58. 58.
    Kierfeld G, Schöps W (1994) MdE und “Heilungsbewährung”, insbesondere bei Krebserkrankungen—in der Begutachtung für die gesetzliche Unfallversicherung. Med Sach 90:43–46Google Scholar
  59. 59.
    Knecht U, Woitowitz HJ (1989) Risk of cancer from the use of tar bitumen in road works. Br J Ind Med 46:24–30PubMedGoogle Scholar
  60. 60.
    Knecht U, Woitowitz HJ (1990) Krebsgefährdung bei Verwendung von Pechbitumen im Straßenbau (PT-AT). Wirtschaftsverlag NW, Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Dortmund, Forschung; Fb 612)Google Scholar
  61. 61.
    Letzel S, Letzel H, Blümner E, Hendrichs A, Sommerburg C (1992) Haut-, Bronchial-, Kehlkopf-, und Harnwegskarzinommorbidität bei Patienten mit berufsbedingter Teerhaut. Schriftenreihe des Hauptverbandes der gewerblichen Berufsgenossenschaften, Sankt AugustinGoogle Scholar
  62. 62.
    Lewalter J, Miksche LW (1992) Empfehlungen zur arbeitsmedizinischen Prävention expositions- und dispositionsbedingter Arbeitsstoff-Beanspruchungen. Verh Dt Ges Arbeitsmed 31:135–139Google Scholar
  63. 63.
    Ma QW, Lin GF, Qin YQ, Lu DR, Golka K, Geller F, et al (2003) GSTP1 A1578G (Ile105Val) polymorphism in benzidine-exposed workers: an association with cytological grading of exfoliated urothelial cells. Pharmacogenetics 13:409–415CrossRefPubMedGoogle Scholar
  64. 64.
    MacCredie M, Stewart JH (1993) Risk factors for kidney cancer in New South Wales. IV. Occupation. Br J Ind Med 50:349–354PubMedGoogle Scholar
  65. 65.
    Maltoni C, Lefemine G, Cotti G, Perino G (1988) Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice. Ann N Y Acad Sci 53:316–342Google Scholar
  66. 66.
    Manz A (1976) Harnwegskarzinome bei Beschäftigten der Gasindustrie. Münch Med Wschr 118:65–68Google Scholar
  67. 67.
    Melick WF, Escue HM, Naryka JJ, Mezera RA, Wheeler EP (1955) The first reported cases of human bladder tumors due to a new carcinogen—Xenylamine. J Urol 74:760–766PubMedGoogle Scholar
  68. 68.
    Moulin JJ, Clavel T, Buclez B, Laffitte-Rigaud G (2000) A mortality study among workers in a French aluminium reduction plant. Int Arch Occup Environ Health 73:323–330CrossRefPubMedGoogle Scholar
  69. 69.
    Mundt KA, Birk T, Burch MT (2003) Critical review of the epidemiological literature on occupational exposure to perchloroethylene and cancer. Int Arch Occup Environ Health 76:473–491PubMedGoogle Scholar
  70. 70.
    Myslak ZW (1990) Azofarbmittel auf der Basis krebserzeugender und -verdächtiger aromatischer Amine Identifikation, Verwendungsbereiche, Herstellungszeiträume Wirtschaftsverlag NW, Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Dortmund, Gefährliche Arbeitsstoffe—GA 35)Google Scholar
  71. 71.
    Myslak ZW, Bolt HM, Brockmann W (1991) Tumors of the urinary bladder in painters: a case-control study. Am J Ind Med 19:705–713PubMedGoogle Scholar
  72. 72.
    NCI Carcinogenesis bioassay of trichloroethylene (1976) CAS No 79-01-6 National Cancer Institute Technical Report Series No 2, Feb 1976 US Dept Health Education, and Welfare, Washington, DC. http://ntp-server.niehs.nih.gov/htdocs/LT_rtps/tr002.pdfGoogle Scholar
  73. 73.
    Norpoth K, Woitowitz HJ (1991) Beruflich verursachte Tumoren. Grundlagen der Entscheidung zur BK-Verdachtsanzeige. Deutscher Ärzteverlag, Köln, pp 25–31Google Scholar
  74. 74.
    NTP Technical report on the toxicology and carcinogenesis studies on tetrachloroethylene (perchloroethylene) (CAS No. 127-18-4) in F344/N rats and B6C3F1 mice (inhalation studies) NTP TR 311 NIH Publication No. 86-2567 (1986) U.S. Department of Health and Human Services. http://ntp-server.niehs.nih.gov/htdocs/LT_rtps/tr311.pdfGoogle Scholar
  75. 75.
    NTP Technical report on the toxicology and carcinogenesis studies of trichloroethylene (CAS No. 79-01-6) in four strains of rats (gavage studies) NTP TR 273 NIH Publication No. 88-2529 (1988) U.S. Department of Health and Human Services. http://ntp-server.niehs.nih.gov/htdocs/LT_rtps/tr273.pdfGoogle Scholar
  76. 76.
    NTP Technical report on the carcinogenesis studies of trichloroethylene (without epichlorohydrin) (CAS No. 79-01-6) in F344/N rats and B6C3F1 mice (gavage studies) NTP TR 243 NIH Publication No. 90-1779 (1990) U.S. Department of Health and Human Services. http://ntp-server.niehs.nih.gov/htdocs/LT_rtps/tr243.pdfGoogle Scholar
  77. 77.
    Olsen JH, Jensen OM (1987) Occupation and risk of cancer in Denmark. An analysis of 93810 cancer cases, 1970–1979. Scand J Work Environ Health 13[Suppl 1]: 1–91Google Scholar
  78. 78.
    Popp W, Schmieding W, Speck M, Vahrenholz C, Norpoth K (1992) Incidence of bladder cancer in a cohort of workers exposed to 4-chloro-o-toluidine while synthesising chlordimeform. Br J Ind Med 49:529–531PubMedGoogle Scholar
  79. 79.
    Pott P (1775) Chirurgical observations relative to the cataract, the polypus of the nose, the cancer of the scrotum, the different kind of ruptures and the mortification of the toes and feet. LondonGoogle Scholar
  80. 80.
    Rinde E, Troll W (1975) Metabolic reduction of benzidine azo dyes to benzidine in the Rhesus monkey. J Natl Cancer Inst 55:181–182Google Scholar
  81. 81.
    Risch HA, Burch JD, Miller AB, Hill GB, Steele R, Howe GR (1988) Occupational factors and the incidence of cancer of the bladder in Canada. Br J Ind Med 45:361–367PubMedGoogle Scholar
  82. 82.
    Robens JF, Dill GS, Ward JM, Joiner JR, Griesemer RA, Douglas JF (1980) Thirteen-week subchronic studies of Direct Blue 6, Direct Black 38 and Direct Brown 95 dyes. Toxicol Appl Pharmacol 54:431–442Google Scholar
  83. 83.
    Roemer HC, Golka K, Schulze H, Loehlein D (2002) Two extrapulmonary neoplasms in a uranium miner. J Roy Soc Med 95:302CrossRefGoogle Scholar
  84. 84.
    Romundstad P, Andersen A, Haldorsen T (2000) Cancer incidence among workers in six Norwegian aluminum plants. Scand J Work Environ Health 26:461–469PubMedGoogle Scholar
  85. 85.
    Rönneberg A, Langmark F (1992) Epidemiologic evidence of cancer in aluminium reduction plant workers. Am J Ind Med 22:573–590PubMedGoogle Scholar
  86. 86.
    Rösler JA, Woitowitz HJ, Woitowitz RH, Rödelsperger K (1994) Tumorrisiken durch Asbest in Deutschland im internationalen Vergleich. Arbeitsmed Sozialmed Umweltmed 29:458–462Google Scholar
  87. 87.
    Schifflers E, Jamart J, Renard V (1987) Tobacco and occupation as risk factors in bladder cancer: a case-control study in southern Belgium. Int J Cancer 39:287–292PubMedGoogle Scholar
  88. 88.
    Schoenberg JB, Stemhagen A, Mogielnicki AP, Altman R, Abe T, Mason TJ (1984) Case-control study of bladder cancer in New Jersey. I. Occupational exposures in white males. J Natl Cancer Inst 72:973–981PubMedGoogle Scholar
  89. 89.
    Schöps W, Golka K, Bolt HM, Kierfeld G (1997) Das Nierenzellkarzinom als Berufserkrankung. Med Sach 93:146–148Google Scholar
  90. 90.
    Seidel A, Grimmer G, Dettbarn G, Jacob J (2001) Urinary excretion of carcinogenic aromatic amines by nonsmokers. Umweltmed Forsch Prax 6:213–220 (in German)Google Scholar
  91. 91.
    Selikoff IJ, Hammond EC, Seidman H (1979) Mortality experience of insulation workers in the United States and Canada, 1943–1976. Ann N Y Acad Sci 330:91–116PubMedGoogle Scholar
  92. 92.
    Sherson D, Svane O, Lyng E (1991) Cancer incidence among foundry workers in Denmark. Arch Environ Health 46:75–81PubMedGoogle Scholar
  93. 93.
    Silverman DT, Hoover RH, Albert S, Graff KM (1983) Occupation and cancer of the lower urinary tract in Detroit. J Natl Cancer Inst 70:237–245PubMedGoogle Scholar
  94. 94.
    Smith AH, Pearce NE, Callas PW (1988) Cancer case-control studies with other cancers as controls. Int J Epidemiol 17:298–306PubMedGoogle Scholar
  95. 95.
    Society of Dyers and Colourists and American Association of Textile Chemists and Colorists (2002) Colour Index, 4th electronical edition www.colour-index.orgGoogle Scholar
  96. 96.
    Sorahan T, Hamilton L, Jackson JR (2000) A further cohort study of workers employed at a factory manufacturing chemicals for the rubber industry, with special reference to the chemicals 2-mercaptobenzothiazole (MBT), aniline, phenyl-beta-naphthylamine and o-toluidine. Occup Environ Med 57:106–115CrossRefPubMedGoogle Scholar
  97. 97.
    Stabbert R, Schafer KH, Biefel C, Rustemeier K (2003) Analysis of aromatic amines in cigarette smoke. Rapid Commun Mass Spectrom 17:2125–2132CrossRefPubMedGoogle Scholar
  98. 98.
    Stasik MJ (1988) Carcinomas of the urinary bladder in a 4-chloro-o-toluidine cohort. Int Arch Occup Environ Health 60:21–24PubMedGoogle Scholar
  99. 99.
    Stasik MJ, Konietzko J, Godlewski A, Fortak W (2000) Current studies of 4-chloro-o-toluidine and chlordimeform carcinogenicity. 26th International Congress on Occupational Health, August 27–September 1, 2000, Singapore. Scientific Programme and Abstracts, p 311Google Scholar
  100. 100.
    Steenland K, Palu S (1999) Cohort mortality study of 57,000 painters and other union members: a 15 year update. Occup Environ Med 56:315–321PubMedGoogle Scholar
  101. 101.
    Steineck G, Plato N, Norell SE, Hogstedt C (1990) Urothelial cancer and some industry-related chemicals: An evaluation on the epidemiologic literature. Am J Ind Med 17:371–391PubMedGoogle Scholar
  102. 102.
    Stern FB, Ruder AM, Chen G (2000) Proportionate mortality among unionized roofers and waterproofers. Am J Ind Med 37:478–492PubMedGoogle Scholar
  103. 103.
    Straif K, Weiland SK, Werner B, Chambless L, Mundt KA, Keil U (1998) Workplace risk factors for cancer in the German rubber industry: Part 2 Mortality from non-respiratory cancers. Occup Environ Med 55:325–332PubMedGoogle Scholar
  104. 104.
    Tola S (1980) Occupational cancer of the urinary bladder. J Toxicol Environ Health 6:1253–1260PubMedGoogle Scholar
  105. 105.
    Vamvakas S, Brüning T, Thomasson B, Lammert M, Baumüller A, Bolt HM, et al (1998) Renal cell cancer correlated with occupational exposure to trichloroethene. J Cancer Res Clin Oncol 124:374–382Google Scholar
  106. 106.
    Vena JE, Fiedler RC (1987) Mortality of a municipal-worker cohort: IV fire fighters. Am J Ind Med 11:671–684PubMedGoogle Scholar
  107. 107.
    Vineis P, Magnani C (1985) Occupation and bladder cancer in males: a case-control study. Int J Cancer 35:599–606PubMedGoogle Scholar
  108. 108.
    Vineis P (2003) This issueGoogle Scholar
  109. 109.
    Weiss T, Ewers U, Flieger A, Angerer J (2000) Innere Belastung der Allgemeinbevölkerung mit Amino- und Nitroaromatischen Verbindungen. Umweltmed Forsch Prax 5:101–106Google Scholar
  110. 110.
    Wynder EL, Onderdonk J, Mantel N (1963) An epidemiological investigation of cancer of the bladder. Cancer 16:1388–1407PubMedGoogle Scholar
  111. 111.
    You XY, Chen JG, Yao YF (1983) A retrospective prospective investigation on bladder cancer in the workers exposed to benzidine in Shanghai dyestuff industry. Tumor 3:197–201 (in Chinese)Google Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Klaus Golka
    • 1
  • Andreas Wiese
    • 1
  • Giorgio Assennato
    • 2
  • Hermann M. Bolt
    • 1
  1. 1.Institute for Occupational Physiology at the University of Dortmund (IfADo)DortmundGermany
  2. 2.Dipartimento di Medicina Interna e Medicina Pubblica, Facolta di Medicina e ChirurgiaUniversita di BariPoliclinicoItaly

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