Journal of Plant Growth Regulation

, Volume 26, Issue 2, pp 160–177 | Cite as

Modulation of Plant Defenses by Ethylene

  • Bruce Adie
  • José Manuel Chico
  • Ignacio Rubio-Somoza
  • Roberto Solano


Ethylene (ET) plays a critical role in the activation of plant defenses against different biotic stresses through its participation in a complex signaling network that includes jasmonic acid (JA), salicylic acid (SA), and abscisic acid (ABA). Pathogen attack, wounding, and herbivory trigger asymmetric activation of this defense signaling network, thereby affecting the final balance of interactions between its components and establishing a targeted response to the initial threat. Ethylene’s contribution to the modulation of this defense network relies on the complexity of the regulation of multigene families involved in ET biosynthesis, signal transduction, and crosstalk and enables the plant to fine-tune its response. The function of the members of these multigene families is tightly regulated at transcriptional, post-transcriptional, and post-translational levels. It is generally accepted that ET cooperates with JA in the activation of defenses against necrotrophic pathogens and antagonizes SA-dependent resistance against biotrophic pathogens. However, this is likely an oversimplified view, because cooperative interactions between ET and SA pathways have been reported and ET has been implicated in the activation of defenses against some biotrophic and hemibiotrophic pathogens. Therefore, deciphering ET’s place in this hormonal network is essential to understanding how the cell orchestrates an optimal response to a specific biotic stress.


Ethylene Plant defense Necrotroph Jasmonic acid Salicylic acid Abscisic acid Hormone crosstalk PRs ERFs GCC box 



This work was financed by grants to R.S. from the Spanish Ministerio de Ciencia y Tecnología (BIO2001-0567, BIO2004-02502, and GEN2003-20218-C02-02), and from the Comunidad de Madrid (07G/0048/2000, 07B/0044/2002, and GR/SAL/0674/2004).

B.A. has been supported by postdoctoral fellowships from the EU (CRISP project HPRN-CT-2000-00093) and from the Spanish Ministerio de Educación y Ciencia (GEN2003-20218-C02-02).

J-M.C. has been supported by postdoctoral contract associated with BIO2004-02502 funded by Spanish Ministerio de Educación y Ciencia.

I.R-S. has been supported by postdoctoral I3P fellowship funded by Consejo Superior de Investigaciones Cientificas (CSIC).


  1. Allen MD, Yamasaki K, Ohme-Takagi M, Tateno M, Suzuki M. 1998. A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA. EMBO J 17:5484–5496PubMedCrossRefGoogle Scholar
  2. Aloni R, Wolf A, Feigenbaum P, Avni A, Klee HJ. 1998. The never ripe mutant provides evidence that tumor-induced ethylene controls the morphogenesis of Agrobacterium tumefaciens-induced crown galls on tomato stems. Plant Physiol 117:841–849PubMedCrossRefGoogle Scholar
  3. Alonso E, de Carvalho Niebel F, Obregon P, Gheysen G, et al. 1995. Differential in vitro DNA binding activity to a promoter element of the gn1 beta-1,3-glucanase gene in hypersensitively reacting tobacco plants. Plant J 7:309–320PubMedCrossRefGoogle Scholar
  4. Alonso JM, Stepanova AN, Solano R, Wisman E, Ferrari S, et al. 2003. Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis. Proc Natl Acad Sci USA 100:2992–2997PubMedCrossRefGoogle Scholar
  5. Anderson JP, Badruzsaufari E, Schenk PM, Manners JM, Desmond OJ, et al. 2004. Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis. Plant Cell 16:3460–3479PubMedCrossRefGoogle Scholar
  6. Arimura G, Ozawa R, Shimoda T, Nishioka T, Boland W, et al. 2000. Herbivory-induced volatiles elicit defence genes in lima bean leaves. Nature 406:512–515PubMedCrossRefGoogle Scholar
  7. Avni A, Bailey BA, Mattoo AK, Anderson JD. 1994. Induction of ethylene biosynthesis in Nicotiana tabacum by a Trichoderma viride xylanase is correlated to the accumulation of 1-aminocyclopropane-1-carboxylic acid (ACC) synthase and ACC oxidase transcripts. Plant Physiol 106:1049–1055PubMedCrossRefGoogle Scholar
  8. Babula D, Misztal LH, Jakubowicz M, Kaczmarek M, Nowak W, et al. 2006. Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues. Theor Appl Genet 112:410–420PubMedCrossRefGoogle Scholar
  9. Baldwin IT. 1998. Jasmonate-induced responses are costly but benefit plants under attack in native populations. Proc Natl Acad Sci USA 95:8113–8118PubMedCrossRefGoogle Scholar
  10. Baldwin IT, Halitschke R, Paschold A, von Dahl CC, Preston CA. 2006. Volatile signaling in plant–plant interactions: “talking trees” in the genomics era. Science 311:812–815PubMedCrossRefGoogle Scholar
  11. Beckman CH. 2000. Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiol Mol Plant Pathol 57:101–110CrossRefGoogle Scholar
  12. Berrocal-Lobo M, Molina A, Solano R. 2002. Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi. Plant J 29:23–32PubMedCrossRefGoogle Scholar
  13. Berrocal-Lobo M, Molina A. 2004. Ethylene response factor 1 mediates Arabidopsis resistance to the soilborne fungus Fusarium oxysporum. Mol Plant Microbe Interact 17:763–770PubMedCrossRefGoogle Scholar
  14. Blume B, Grierson D. 1997. Expression of ACC oxidase promoter-GUS fusions in tomato and Nicotiana plumbaginifolia regulated by developmental and environmental stimuli. Plant J 12:731–746PubMedCrossRefGoogle Scholar
  15. Boter M, Ruiz-Rivero O, Abdeen A, Prat S. 2004. Conserved MYC transcription factors play a key role in jasmonate signaling both in tomato and Arabidopsis. Genes Dev 18:1577–1591PubMedCrossRefGoogle Scholar
  16. Bradley DJ, Kjellbom P, Lamb CJ. 1992. Elicitor- and wound-induced oxidative cross-linking of a proline-rich plant cell wall protein: a novel, rapid defense response. Cell 70:21–30PubMedCrossRefGoogle Scholar
  17. Brodersen P, Petersen M, Bjorn Nielsen H, Zhu S, et al. 2006. Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J 47:532–546PubMedGoogle Scholar
  18. Broekaert WF, Delaure SL, De Bolle MF, Cammue BP. 2006. The role of ethylene in host-pathogen interactions. Annu Rev Phytopathol 44:393–416PubMedCrossRefGoogle Scholar
  19. Broglie KE, Biddle P, Cressman R, Broglie R. 1989. Functional analysis of DNA sequences responsible for ethylene regulation of a bean chitinase gene in transgenic tobacco. Plant Cell 1:599–607PubMedCrossRefGoogle Scholar
  20. Brown RL, Kazan K, McGrath KC, Maclean DJ, Manners JM. 2003. A role for the GCC-box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis. Plant Physiol 132:1020–1032PubMedCrossRefGoogle Scholar
  21. Buttner M, Singh KB. 1997. Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP), an ethylene-inducible, GCC box DNA-binding protein interacts with an ocs element binding protein. Proc Natl Acad Sci USA 94:5961–5966PubMedCrossRefGoogle Scholar
  22. Chae HS, Kieber JJ. 2005. Eto Brute? Role of ACS turnover in regulating ethylene biosynthesis. Trends Plant Sci 10:291–296PubMedCrossRefGoogle Scholar
  23. Chakravarthy S, Tuori RP, D’Ascenzo MD, Fobert PR, Despres C, et al. 2003. The tomato transcription factor Pti4 regulates defense-related gene expression via GCC box and non-GCC box cis elements. Plant Cell 15:3033–3050PubMedCrossRefGoogle Scholar
  24. Chao Q, Rothenberg M, Solano R, Roman G, Terzaghi W, et al. 1997. Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins. Cell 89:1133–1144PubMedCrossRefGoogle Scholar
  25. Chen W, Provart NJ, Glazebrook J, Katagiri F, Chang HS, et al. 2002. Expression profile matrix of Arabidopsis transcription factor genes suggests their putative functions in response to environmental stresses. Plant Cell 14:559–574PubMedCrossRefGoogle Scholar
  26. Chen G, Alexander L, Grierson D. 2004. Constitutive expression of EIL-like transcription factor partially restores ripening in the ethylene-insensitive Nr tomato mutant. J Exp Bot 55:1491–1497PubMedCrossRefGoogle Scholar
  27. Cheong YH, Chang HS, Gupta R, Wang X, Zhu T, et al. 2002. Transcriptional profiling reveals novel interactions between wounding, pathogen, abiotic stress, and hormonal responses in Arabidopsis. Plant Physiol 129:661–677PubMedCrossRefGoogle Scholar
  28. Cheong YH, Moon BC, Kim JK, Kim CY, Kim MC, et al. 2003. BWMK1, a rice mitogen-activated protein kinase, locates in the nucleus and mediates pathogenesis-related gene expression by activation of a transcription factor. Plant Physiol 132:1961–1972PubMedCrossRefGoogle Scholar
  29. Clarke JD, Volko SM, Ledford H, Ausubel FM, Dong X. 2000. Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in Arabidopsis. Plant Cell 12:2175–2190PubMedCrossRefGoogle Scholar
  30. Cohn JR, Martin GB. 2005. Pseudomonas syringae pv. tomato type III effectors AvrPto and AvrPtoB promote ethylene-dependent cell death in tomato. Plant J 44:139–154PubMedGoogle Scholar
  31. Cui J, Bahrami AK, Pringle EG, Hernandez-Guzman G, Bender CL, et al. 2005. Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores. Proc Natl Acad Sci USA 102:1791–1796PubMedCrossRefGoogle Scholar
  32. de Bruxelles GL, Roberts MR. 2001. Signals regulating multiple responses to wounding and herbivores. Crit Rev Plant Sci 20:487–521CrossRefGoogle Scholar
  33. De Vos M, Van Zaanen W, Koornneef A, Korzelius J, Dicke M, et al. 2006. Herbivore-induced resistance against microbial pathogens in Arabidopsis. Plant Physiol 142:352–363PubMedCrossRefGoogle Scholar
  34. Devadas SK, Enyedi A, Raina R. 2002. The Arabidopsis hrl1 mutation reveals novel overlapping roles for salicylic acid, jasmonic acid and ethylene signalling in cell death and defence against pathogens. Plant J 30:467–480PubMedCrossRefGoogle Scholar
  35. Devoto A, Nieto-Rostro M, Xie D, Ellis C, Harmston R, et al. 2002. COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis. Plant J 32:457–466PubMedCrossRefGoogle Scholar
  36. Diaz J, ten Have A, van Kan JA. 2002. The role of ethylene and wound signaling in resistance of tomato to Botrytis cinerea. Plant Physiol 129:1341–1351PubMedCrossRefGoogle Scholar
  37. Dixon RA. 2001. Natural products and plant disease resistance. Nature 411:843–847PubMedCrossRefGoogle Scholar
  38. Ellis C, Turner JG. 2001. The Arabidopsis mutant cev1 has constitutively active jasmonate and ethylene signal pathways and enhanced resistance to pathogens. Plant Cell 13:1025–1033PubMedCrossRefGoogle Scholar
  39. Ellis C, Karafyllidis I, Wasternack C, Turner JG. 2002. The Arabidopsis mutant cev1 links cell wall signaling to jasmonate and ethylene responses. Plant Cell 14:1557–1566PubMedCrossRefGoogle Scholar
  40. Engelberth J, Alborn HT, Schmelz EA, Tumlinson JH. 2004. Airborne signals prime plants against insect herbivore attack. Proc Natl Acad Sci USA 101:1781–1785PubMedCrossRefGoogle Scholar
  41. Esquerre-Tugaye MT, Lafitte C, Mazau D, Toppan A, Touze A. 1979. Cell surfaces in plant–microorganism interactions: II. Evidence for the accumulation of hydroxyproline-rich glycoproteins in the cell wall of diseased plants as a defense mechanism. Plant Physiol 64:320–326PubMedGoogle Scholar
  42. Eyal Y, Meller Y, Lev-Yadun S, Fluhr R. 1993. A basic-type PR-1 promoter directs ethylene responsiveness, vascular and abscission zone-specific expression. Plant J 4:225–234PubMedCrossRefGoogle Scholar
  43. Fan X, Mattheis JP, Roberts RG. 2000. Biosynthesis of phytoalexin in carrot root requires ethylene action. Physiol Plant 110:450–454CrossRefGoogle Scholar
  44. Farmer EE. 2001. Surface-to-air signals. Nature 411:854–856PubMedCrossRefGoogle Scholar
  45. Farmer EE, Ryan CA. 1990. Interplant communication: airborne methyl jasmonate induces synthesis of proteinase-inhibitors in plant leaves. Proc Natl Acad Sci USA 87:7713–7716PubMedCrossRefGoogle Scholar
  46. Finkelstein RR, Gibson SI. 2002. ABA and sugar interactions regulating development: cross-talk or voices in a crowd? Curr Opin Plant Biol 5:26–32PubMedCrossRefGoogle Scholar
  47. Frye CA, Innes RW. 1998. An Arabidopsis mutant with enhanced resistance to powdery mildew. Plant Cell 10:947–956PubMedCrossRefGoogle Scholar
  48. Frye CA, Tang D, Innes RW. 2001. Negative regulation of defense responses in plants by a conserved MAPKK kinase. Proc Natl Acad Sci USA 98:373–378PubMedCrossRefGoogle Scholar
  49. Fujimoto SY, Ohta M, Usui A, Shinshi H, Ohme-Takagi M. 2000. Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell 12:393–404PubMedCrossRefGoogle Scholar
  50. Gingerich DJ, Gagne JM, Salter DW, Hellmann H, Estelle M, et al. 2005. Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis. J Biol Chem 280:18810–18821PubMedCrossRefGoogle Scholar
  51. Glazebrook J. 2005. Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. Annu Rev Phytopathol 43:205–227PubMedCrossRefGoogle Scholar
  52. Glazebrook J, Ausubel FM. 1994. Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens. Proc Natl Acad Sci USA 91:8955–8959PubMedCrossRefGoogle Scholar
  53. Glazebrook J, Zook M, Mert F, Kagan I, Rogers EE, et al. 1997. Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance. Genetics 146:381–392PubMedGoogle Scholar
  54. Gu YQ, Yang C, Thara VK, Zhou J, Martin GB. 2000. Pti4 is induced by ethylene and salicylic acid, and its product is phosphorylated by the Pto kinase. Plant Cell 12:771–786PubMedCrossRefGoogle Scholar
  55. Gu YQ, Wildermuth MC, Chakravarthy S, Loh YT, Yang C, et al. 2002. Tomato transcription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis. Plant Cell 14:817–831PubMedCrossRefGoogle Scholar
  56. Guo H, Ecker JR. 2003. Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor. Cell 115(6):667–77PubMedCrossRefGoogle Scholar
  57. Guo H, Ecker JR. 2004. The ethylene signaling pathway: new insights. Curr Opin Plant Biol 7:40–49PubMedCrossRefGoogle Scholar
  58. Gutterson N, Reuber TL. 2004. Regulation of disease resistance pathways by AP2/ERF transcription factors. Curr Opin Plant Biol 7:465–471PubMedCrossRefGoogle Scholar
  59. Ham BK, Park JM, Lee SB, Kim MJ, Lee IJ, et al. 2006. Tobacco Tsip1, a DnaJ-type Zn finger protein, is recruited to and potentiates Tsi1-mediated transcriptional activation. Plant Cell 18:2005–2020PubMedCrossRefGoogle Scholar
  60. Hao D, Ohme-Takagi M, Sarai A. 1998. Unique mode of GCC box recognition by the DNA-binding domain of ethylene-responsive element-binding factor (ERF domain) in plant. J Biol Chem 273:26857–26861PubMedCrossRefGoogle Scholar
  61. Hart CM, Nagy F, Meins F Jr. 1993. A 61 bp enhancer element of the tobacco beta-1,3-glucanase B gene interacts with one or more regulated nuclear proteins. Plant Mol Biol 21:121–131PubMedCrossRefGoogle Scholar
  62. Hase S, Van Pelt J, Van Loon C, Pieterse CMJ. 2003. Colonization of Arabidopsis roots by Pseudomonas fluorescens primes the plant to produce higher levels of ethylene upon pathogen infection. Physiol Mol Plant Pathol 62:219–226CrossRefGoogle Scholar
  63. Itzhaki H, Maxson JM, Woodson WR. 1994. An ethylene-responsive enhancer element is involved in the senescence-related expression of the carnation glutathione-S-transferase (GST1) gene. Proc Natl Acad Sci USA 91:8925–8929PubMedCrossRefGoogle Scholar
  64. Jackson PA, Galinha CI, Pereira CS, Fortunato A, Soares NC, et al. 2001. Rapid deposition of extensin during the elicitation of grapevine callus cultures is specifically catalyzed by a 40-kilodalton peroxidase. Plant Physiol 127:1065–1076PubMedCrossRefGoogle Scholar
  65. Kahl J, Siemens DH, Aerts RJ, Gabler R, Kuhnemann F, et al. 2000. Herbivore-induced ethylene suppresses a direct defense but not a putative indirect defense against an adapted herbivore. Planta 210:336–342PubMedCrossRefGoogle Scholar
  66. Kamo T, Hirai N, Tsuda M, Fujioka D, Ohigashi H. 2000. Changes in the content and biosynthesis of phytoalexins in banana fruit. Biosci Biotechnol Biochem 64:2089–2098PubMedCrossRefGoogle Scholar
  67. Karban R, Baldwin IT, Baxter KJ, Laue G, Felton GW. 2000. Communication between plants: induced resistance in wild tobacco plants following clipping of neighboring sagebrush. Oecologia 125:66–71CrossRefGoogle Scholar
  68. Karban R, Maron J, Felton GW, Ervin G, Eichenseer H. 2003. Herbivore damage to sagebrush induces resistance in wild tobacco: evidence for eavesdropping between plants. Oikos 100:325–332CrossRefGoogle Scholar
  69. Kazan K. 2006. Negative regulation of defence and stress genes by EAR-motif-containing repressors. Trends Plant Sci 11:109–112PubMedCrossRefGoogle Scholar
  70. Kessler A, Baldwin IT. 2001. Defensive function of herbivore-induced plant volatile emissions in nature. Science 291:2141–2144PubMedCrossRefGoogle Scholar
  71. Kim YS, Choi D, Lee MM, Lee SH, Kim WT. 1998. Biotic and abiotic stress-related expression of 1-aminocyclopropane-1-carboxylate oxidase gene family in Nicotiana glutinosa L. Plant Cell Physiol 39:565–573PubMedGoogle Scholar
  72. Knoester M, van Loon LC, van den Heuvel J, Hennig J, Bol JF, et al. 1998. Ethylene-insensitive tobacco lacks nonhost resistance against soil-borne fungi. Proc Natl Acad Sci USA 95:1933–1937PubMedCrossRefGoogle Scholar
  73. Kunkel BN, Brooks DM. 2002. Cross talk between signaling pathways in pathogen defense. Curr Opin Plant Biol 5:325–331PubMedCrossRefGoogle Scholar
  74. Lawton K, Weymann K, Friedrich L, Vernooij B, Uknes S, et al. 1995. Systemic acquired resistance in Arabidopsis requires salicylic acid but not ethylene. Mol Plant Microbe Interact 8:863–870PubMedGoogle Scholar
  75. Lee JH, Hong JP, Oh SK, Lee S, Choi D, et al. 2004. The ethylene-responsive factor like protein 1 (CaERFLP1) of hot pepper (Capsicum annuum L.) interacts in vitro with both GCC and DRE/CRT sequences with different binding affinities: possible biological roles of CaERFLP1 in response to pathogen infection and high salinity conditions in transgenic tobacco plants. Plant Mol Biol 55:61–81PubMedCrossRefGoogle Scholar
  76. Lehman A, Black R, Ecker JR. 1996. HOOKLESS1, an ethylene response gene, is required for differential cell elongation in the Arabidopsis hypocotyl. Cell 85:183–194PubMedCrossRefGoogle Scholar
  77. Leon P, Sheen J. 2003. Sugar and hormone connections. Trends Plant Sci 8:110–116PubMedCrossRefGoogle Scholar
  78. Liu JH, Lee-Tamon SH, Reid DM. 1997. Differential and wound-inducible expression of 1-aminocylopropane-1-carboxylate oxidase genes in sunflower seedlings. Plant Mol Biol 34:923–933PubMedCrossRefGoogle Scholar
  79. Liu Y, Zhang S. 2004. Phosphorylation of 1-aminocyclopropane-1-carboxylic acid synthase by MPK6, a stress-responsive mitogen-activated protein kinase, induces ethylene biosynthesis in Arabidopsis. Plant Cell 16:3386–3399PubMedCrossRefGoogle Scholar
  80. Lorenzo O, Piqueras R, Sanchez-Serrano JJ, Solano R. 2003. ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell 15:165–178PubMedCrossRefGoogle Scholar
  81. Lorenzo O, Chico JM, Sanchez-Serrano JJ, Solano R. 2004. JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis. Plant Cell 16:1938–1950PubMedCrossRefGoogle Scholar
  82. Lorenzo O, Solano R. 2005. Molecular players regulating the jasmonate signalling network. Curr Opin Plant Biol 8:532–540PubMedCrossRefGoogle Scholar
  83. Magnani E, Sjolander K, Hake S. 2004. From endonucleases to transcription factors: evolution of the AP2 DNA binding domain in plants. Plant Cell 16:2265–2277PubMedCrossRefGoogle Scholar
  84. Maleck K, Levine A, Eulgem T, Morgan A, Schmid J, et al. 2000. The transcriptome of Arabidopsis thaliana during systemic acquired resistance. Nat Genet 26:403–410PubMedCrossRefGoogle Scholar
  85. McGrath KC, Dombrecht B, Manners JM, Schenk PM, Edgar CI, et al. 2005. Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. Plant Physiol 139:949–959PubMedCrossRefGoogle Scholar
  86. Meller Y, Sessa G, Eyal Y, Fluhr R. 1993. DNA-protein interactions on a cis-DNA element essential for ethylene regulation. Plant Mol Biol 23:453–463PubMedCrossRefGoogle Scholar
  87. Montgomery J, Goldman S, Deikman J, Margossian L, Fischer RL. 1993. Identification of an ethylene-responsive region in the promoter of a fruit ripening gene. Proc Natl Acad Sci USA 90:5939–5943PubMedCrossRefGoogle Scholar
  88. Morrissey JP, Osbourn AE. 1999. Fungal resistance to plant antibiotics as a mechanism of pathogenesis. Microbiol Mol Biol Rev 63:708–724PubMedGoogle Scholar
  89. Nakano T, Suzuki K, Fujimura T, Shinshi H. 2006a. Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol 140: 411–432CrossRefGoogle Scholar
  90. Nakano T, Suzuki K, Ohtsuki N, Tsujimoto Y, Fujimura T, et al. 2006b. Identification of genes of the plant-specific transcription-factor families cooperatively regulated by ethylene and jasmonate in Arabidopsis thaliana. J Plant Res 119:407–413CrossRefGoogle Scholar
  91. Nakazato Y, Tamogami S, Kawai H, Hasegawa M, Kodama O. 2000. Methionine-induced phytoalexin production in rice leaves. Biosci Biotechnol Biochem 64:577–583PubMedCrossRefGoogle Scholar
  92. Nemhauser JL, Hong F, Chory J. 2006. Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses. Cell 126:467–475PubMedCrossRefGoogle Scholar
  93. Nickstadt A, Thomma BPHJ, Feussner I, Kangasjärvi J, Zeier J, et al. 2004. The jasmonate-insensitive mutant jin1 shows increased resistance to biotrophic as well as necrotrophic pathogens. Mol Plant Pathol 5:425–434CrossRefGoogle Scholar
  94. Nie X, Singh RP, Tai GC. 2002. Molecular characterization and expression analysis of 1-aminocyclopropane-1-carboxylate oxidase homologs from potato under abiotic and biotic stresses. Genome 45:905–913PubMedCrossRefGoogle Scholar
  95. Nimchuk Z, Eulgem T, Holt BF 3rd, Dangl JL. 2003. Recognition and response in the plant immune system. Annu Rev Genet 37:579–609PubMedCrossRefGoogle Scholar
  96. O’Donnell PJ, Calvert C, Atzorn R, Wasternack C, Leyser HMO, et al. 1996. Ethylene as a signal mediating the wound response of tomato plants. Science 274:1914–1917PubMedCrossRefGoogle Scholar
  97. O’Donnell PJ, Jones JB, Antoine FR, Ciardi J, Klee HJ. 2001. Ethylene-dependent salicylic acid regulates an expanded cell death response to a plant pathogen. Plant J 25:315–323PubMedCrossRefGoogle Scholar
  98. Oh IS, Park AR, Bae MS, Kwon SJ, Kim YS, et al. 2005. Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola. Plant Cell 17:2832–2847PubMedCrossRefGoogle Scholar
  99. Ohme-Takagi M, Shinshi H. 1990. Structure and expression of a tobacco beta-1,3-glucanase gene. Plant Mol Biol 15:941–946PubMedCrossRefGoogle Scholar
  100. Ohme-Takagi M, Shinshi H. 1995. Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element. Plant Cell 7:173–182PubMedCrossRefGoogle Scholar
  101. Ohta M, Matsui K, Hiratsu K, Shinshi H, Ohme-Takagi M. 2001. Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Plant Cell 13:1959–1968PubMedCrossRefGoogle Scholar
  102. Onate-Sanchez L, Singh KB. 2002. Identification of Arabidopsis ethylene-responsive element binding factors with distinct induction kinetics after pathogen infection. Plant Physiol 128:1313–1322PubMedCrossRefGoogle Scholar
  103. Park JM, Park CJ, Lee SB, Ham BK, Shin R, et al. 2001. Overexpression of the tobacco Tsi1 gene encoding an EREBP/AP2-type transcription factor enhances resistance against pathogen attack and osmotic stress in tobacco. Plant Cell 13:1035–1046PubMedCrossRefGoogle Scholar
  104. Peleman J, Boerjan W, Engler G, Seurinck J, Botterman J, et al. 1989. Strong cellular preference in the expression of a housekeeping gene of Arabidopsis thaliana encoding S-adenosylmethionine synthetase. Plant Cell 1:81–93PubMedCrossRefGoogle Scholar
  105. Peñacortés H, Albrecht T, Prat S, Weiler EW, Willmitzer L. 1993. Aspirin prevents wound-induced gene-expression in tomato leaves by blocking jasmonic acid biosynthesis. Planta 191:123–128Google Scholar
  106. Penmetsa RV, Cook DR. 1997. A legume ethylene-insensitive mutant hyperinfected by its rhizobial symbiont. Science 275:527–530PubMedCrossRefGoogle Scholar
  107. Penninckx IA, Eggermont K, Terras FR, Thomma BP, De Samblanx GW, et al. 1996. Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway. Plant Cell 8:2309–2323PubMedCrossRefGoogle Scholar
  108. Penninckx IA, Thomma BP, Buchala A, Metraux JP, Broekaert WF. 1998. Concomitant activation of jasmonate and ethylene response pathways is required for induction of a plant defensin gene in Arabidopsis. Plant Cell 10:2103–2113PubMedCrossRefGoogle Scholar
  109. Pierik R, Whitelam GC, Voesenek LA, de Kroon H, Visser EJ. 2004. Canopy studies on ethylene-insensitive tobacco identify ethylene as a novel element in blue light and plant–plant signalling. Plant J 38:310–319PubMedCrossRefGoogle Scholar
  110. Pierik R, Tholen D, Poorter H, Visser EJ, Voesenek LA. 2006. The Janus face of ethylene: growth inhibition and stimulation. Trends Plant Sci 11:176–183PubMedCrossRefGoogle Scholar
  111. Pieterse CM, van Wees SC, van Pelt JA, Knoester M, Laan R, et al. 1998. A novel signaling pathway controlling induced systemic resistance in Arabidopsis. Plant Cell 10:1571–1580PubMedCrossRefGoogle Scholar
  112. Pieterse CMJ, Van Pelt JA, Ton J, Parchmann S, Mueller MJ, et al. 2000. Rhizobacteria-mediated induced systemic resistance (ISR) in Arabidopsis requires sensitivity to jasmonate and ethylene but is not accompanied by an increase in their production. Physiol Mol Plant Pathol 57:123–134CrossRefGoogle Scholar
  113. Potuschak T, Lechner E, Parmentier Y, Yanagisawa S, Grava S. 2003. EIN3-dependent regulation of plant ethylene hormone signaling by two Arabidopsis F box proteins: EBF1 and EBF2. Cell 115:679–689PubMedCrossRefGoogle Scholar
  114. Riechmann JL, Meyerowitz EM. 1998. The AP2/EREBP family of plant transcription factors. Biol Chem 379:633–646PubMedGoogle Scholar
  115. Riechmann JL, Heard J, Martin G, Reuber L, Jiang C, et al. 2000. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290:2105–2110PubMedCrossRefGoogle Scholar
  116. Rieu I, Mariani C, Weterings K. 2003. Expression analysis of five tobacco EIN3 family members in relation to tissue-specific ethylene responses. J Exp Bot 54:2239–2244PubMedCrossRefGoogle Scholar
  117. Robinette D, Matthysse AG. 1990. Inhibition by Agrobacterium tumefaciens and Pseudomonas savastanoi of development of the hypersensitive response elicited by Pseudomonas syringae pv phaseolicola. J Bacteriol 172:5742–5749PubMedGoogle Scholar
  118. Roby D, Toppan A, Esquerre-Tugaye MT. 1985. Cell surfaces in plant–microorganism interactions: V. Elicitors of fungal and of plant origin trigger the synthesis of ethylene and of cell wall hydroxyproline-rich glycoprotein in plants. Plant Physiol 77:700–704PubMedGoogle Scholar
  119. Roby D, Broglie K, Gaynor J, Broglie R. 1991. Regulation of a chitinase gene promoter by ethylene and elicitors in bean protoplasts. Plant Physiol 97:433–439PubMedGoogle Scholar
  120. Rojo E, Leon J, Sanchez-Serrano JJ. 1999. Cross-talk between wound signalling pathways determines local versus systemic gene expression in Arabidopsis thaliana. Plant J 20:135–142PubMedCrossRefGoogle Scholar
  121. Rojo E, Solano R, Sanchez-Serrano JJ. 2003. Interactions between signaling compounds involved in plant defense. J Plant Growth Regul 22:82–98CrossRefGoogle Scholar
  122. Ruther J, Kleier S. 2005. Plant–plant signaling: ethylene synergizes volatile emission in Zea mays induced by exposure to (Z)-3-Hexen-1-ol. J Chem Ecol 31:2217–2222PubMedCrossRefGoogle Scholar
  123. Sakuma Y, Liu Q, Dubouzet JG, Abe H, Shinozaki K, et al. 2002. DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression. Biochem Biophys Res Commun 290:998–1009PubMedCrossRefGoogle Scholar
  124. Samac DA, Hironaka CM, Yallaly PE, Shah DM. 1990. Isolation and characterization of the genes encoding basic and acidic chitinase in Arabidopsis thaliana. Plant Physiol 93:907–914PubMedGoogle Scholar
  125. Sato T, Theologis A. 1989. Cloning the mRNA encoding 1-aminocyclopropane-1-carboxylate synthase, the key enzyme for ethylene biosynthesis in plants. Proc Natl Acad Sci USA 86:6621–6625PubMedCrossRefGoogle Scholar
  126. Schenk PM, Kazan K, Wilson I, Anderson JP, Richmond T, et al. 2000. Coordinated plant defense responses in Arabidopsis revealed by microarray analysis. Proc Natl Acad Sci USA 97:11655–11660PubMedCrossRefGoogle Scholar
  127. Schmelz EA, Alborn HT, Tumlinson JH. 2003. Synergistic interactions between volicitin, jasmonic acid and ethylene mediate insect-induced volatile emission in Zea mays. Physiol Plant 117:403–412PubMedCrossRefGoogle Scholar
  128. Shinshi H, Usami S, Ohme-Takagi M. 1995. Identification of an ethylene-responsive region in the promoter of a tobacco class I chitinase gene. Plant Mol Biol 27:923–932PubMedCrossRefGoogle Scholar
  129. Showalter AM. 1993. Structure and function of plant cell wall proteins. Plant Cell 5:9–23PubMedCrossRefGoogle Scholar
  130. Solano R, Stepanova A, Chao Q, Ecker JR. 1998. Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1. Genes Dev 12:3703–3714PubMedGoogle Scholar
  131. Song CP, Agarwal M, Ohta M, Guo Y, Halfter U, et al. 2005. Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Plant Cell 17:2384–2396PubMedCrossRefGoogle Scholar
  132. Spanu P, Grosskopf DG, Felix G, Boller T. 1994. The apparent turnover of 1-aminocyclopropane-1-carboxylate synthase in tomato cells is regulated by protein phosphorylation and dephosphorylation. Plant Physiol 106:529–535PubMedGoogle Scholar
  133. Spoel SH, Koornneef A, Claessens SM, Korzelius JP, Van Pelt JA, et al. 2003. NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol. Plant Cell 15:760–770PubMedCrossRefGoogle Scholar
  134. Sreedharan A, Penaloza-Vazquez A, Kunkel BN, Bender CL. 2006. CorR regulates multiple components of virulence in Pseudomonas syringae pv. tomato DC3000. Mol Plant Microbe Interact 19:768–779PubMedCrossRefGoogle Scholar
  135. Staswick PE, Yuen GY, Lehman CC. 1998. Jasmonate signaling mutants of Arabidopsis are susceptible to the soil fungus Pythium irregulare. Plant J 15:747–754PubMedCrossRefGoogle Scholar
  136. Stogios PJ, Downs GS, Jauhal JJ, Nandra SK, Prive GG. 2005. Sequence and structural analysis of BTB domain proteins. Genome Biol 6:R82PubMedCrossRefGoogle Scholar
  137. Stotz HU, Pittendrigh BR, Kroymann J, Weniger K, Fritsche J, et al. 2000. Induced plant defense responses against chewing insects. Ethylene signaling reduces resistance of Arabidopsis against Egyptian cotton worm but not diamondback moth. Plant Physiol 124:1007–1018PubMedCrossRefGoogle Scholar
  138. Sun J, Cardoza V, Mitchell DM, Bright L, Oldroyd G, Harris JM. 2006. Crosstalk between jasmonic acid, ethylene and Nod factor signaling allows integration of diverse inputs for regulation of nodulation. Plant J 46:961–970PubMedCrossRefGoogle Scholar
  139. Takeuchi Y, Yoshikawa M, Takeba G, Tanaka K, Shibata D, et al. 1990. Molecular cloning and ethylene induction of mRNA encoding a phytoalexin elicitor-releasing factor, beta-1,3-endoglucanase, in soybean. Plant Physiol 93:673–682PubMedGoogle Scholar
  140. Thomma B, Eggermont K, Penninckx I, Mauch-Mani B, Vogelsang R, et al. 1998. Separate jasmonate-dependent and salicylate-dependent defense-response pathways in Arabidopsis are essential for resistance to distinct microbial pathogens. Proc Natl Acad Sci USA 95:15107–15111PubMedCrossRefGoogle Scholar
  141. Thomma BP, Eggermont K, Tierens KF, Broekaert WF. 1999. Requirement of functional ethylene-insensitive 2 gene for efficient resistance of Arabidopsis to infection by Botrytis cinerea. Plant Physiol 121:1093–1102PubMedCrossRefGoogle Scholar
  142. Thomma BP, Penninckx IA, Broekaert WF, Cammue BP. 2001. The complexity of disease signaling in Arabidopsis. Curr Opin Immunol 13:63–68PubMedCrossRefGoogle Scholar
  143. Thomma BP, Cammue BP, Thevissen K. 2002. Plant defensins. Planta 216:193–202PubMedCrossRefGoogle Scholar
  144. Tieman DM, Ciardi JA, Taylor MG, Klee HJ. 2001. Members of the tomato LeEIL (EIN3-like) gene family are functionally redundant and regulate ethylene responses throughout plant development. Plant J 26:47–58PubMedCrossRefGoogle Scholar
  145. Ton J, Pieterse CMJ, Van Loon LC. 1999. Identification of a locus in Arabidopsis controlling both the expression of rhizobacteria-mediated induced systemic resistance (ISR) and basal resistance against Pseudomonas syringae pv. tomato. Mol Plant-Microbe Interact 12:911–918PubMedCrossRefGoogle Scholar
  146. Ton J, Davison S, Van Wees SCM, Van Loon LC, Pieterse CMJ. 2001. The Arabidopsis ISR1 locus controlling rhizobacteria-mediated induced systemic resistance is involved in ethylene signaling. Plant Physiol 125:652–661PubMedCrossRefGoogle Scholar
  147. Ton J, Mauch-Mani B. 2004. Beta-amino-butyric acid-induced resistance against necrotrophic pathogens is based on ABA-dependent priming for callose. Plant J 38:119–130PubMedCrossRefGoogle Scholar
  148. Toppan A, Roby D, Esquerre-Tugaye MT. 1982. Cell surfaces in plant-microorganism interactions : III. In vivo effect of ethylene on hydroxyproline-rich glycoprotein accumulation in the cell wall of diseased plants. Plant Physiol 70:82–86PubMedGoogle Scholar
  149. Tournier B, Sanchez-Ballesta MT, Jones B, Pesquet E, Regad F, et al. 2003. New members of the tomato ERF family show specific expression pattern and diverse DNA-binding capacity to the GCC box element. FEBS Lett 550:149–154PubMedCrossRefGoogle Scholar
  150. Tscharntke T, Thiessen S, Dolch R, Boland W. 2001. Herbivory, induced resistance, and interplant signal transfer in Alnus glutinosa. Biochem Systematics Ecol 29:1025–1047CrossRefGoogle Scholar
  151. Tsuchisaka A, Theologis A. 2004a. Heterodimeric interactions among the 1-amino-cyclopropane-1-carboxylate synthase polypeptides encoded by the Arabidopsis gene family. Proc Natl Acad Sci USA 101:2275–2280CrossRefGoogle Scholar
  152. Tsuchisaka A, Theologis A. 2004b. Unique and overlapping expression patterns among the Arabidopsis 1-amino-cyclopropane-1-carboxylate synthase gene family members. Plant Physiol 136:2982–3000CrossRefGoogle Scholar
  153. Tsuji J, Jackson EP, Gage DA, Hammerschmidt R, Somerville SC. 1992. Phytoalexin accumulation in Arabidopsis thaliana during the hypersensitive reaction to Pseudomonas syringae pv syringae. Plant Physiol 98:1304–1309PubMedCrossRefGoogle Scholar
  154. Turner JG, Ellis C, Devoto A. 2002. The jasmonate signal pathway. Plant Cell 14(Suppl):S153–S164PubMedGoogle Scholar
  155. Valls M, Genin S, Boucher C. 2006. Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum. PLoS Pathog 25:798–807Google Scholar
  156. van Loon LC, Bakker PAHM, Pieterse CMJ. 1998. Systemic resistance induced by rhizosphere bacteria. Annu Rev Phytopathol 36:453–483PubMedCrossRefGoogle Scholar
  157. van Loon LC, van Strein EA. 1999. The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins. Physiol Mol Plant Pathol 55:85–97CrossRefGoogle Scholar
  158. van Loon LC, Geraats BP, Linthorst HJ. 2006. Ethylene as a modulator of disease resistance in plants. Trends Plant Sci 11:184–191PubMedCrossRefGoogle Scholar
  159. Van Zhong G, Burns JK. 2003. Profiling ethylene-regulated gene expression in Arabidopsis thaliana by microarray analysis. Plant Mol Biol 53:117–131PubMedCrossRefGoogle Scholar
  160. VanderMolen GE, Labavitch JM, Strand LL, DeVay JE. 1983. Pathogen-induced vascular gels: Ethylene as a host intermediate. Physiol Plant 59:573–580CrossRefGoogle Scholar
  161. VanderMolen GE, Labavitch JM, DeVay JE. 1986. Fusarium-induced vascular gels from banana roots—a partial chemical characterization. Physiol Plant 66:298–302CrossRefGoogle Scholar
  162. Veereshlingam H, Haynes JG, Penmetsa RV, Cook DR, Sherrier DJ, et al. 2004. nip, a symbiotic Medicago truncatula mutant that forms root nodules with aberrant infection threads and plant defense-like response. Plant Physiol 136:3692–3702PubMedCrossRefGoogle Scholar
  163. Verberne MC, Hoekstra J, Bol JF, Linthorst HJ. 2003. Signaling of systemic acquired resistance in tobacco depends on ethylene perception. Plant J 35:27–32PubMedCrossRefGoogle Scholar
  164. Veselov D, Langhans M, Hartung W, Aloni R, Feussner I, et al. 2003. Development of Agrobacterium tumefaciens C58-induced plant tumors and impact on host shoots are controlled by a cascade of jasmonic acid, auxin, cytokinin, ethylene and abscisic acid. Planta 216:512–522PubMedGoogle Scholar
  165. Wang KL, Li H, Ecker JR. 2002. Ethylene biosynthesis and signaling networks. Plant Cell 14(Suppl):S131–S151PubMedGoogle Scholar
  166. Wang KL, Yoshida H, Lurin C, Ecker JR. 2004. Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Nature 428:945–950PubMedCrossRefGoogle Scholar
  167. Weber H, Bernhardt A, Dieterle M, Hano P, Mutlu A, et al. 2005. Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family. Plant Physiol 137:83–93PubMedCrossRefGoogle Scholar
  168. Weingart H, Ullrich H, Geider K, Volksch B. 2001. The role of ethylene production in virulence of Pseudomonas syringae pvs. glycinea and phaseolicola. Phytopathology 91:511–518CrossRefPubMedGoogle Scholar
  169. Winz RA, Baldwin IT. 2001. Molecular interactions between the specialist herbivore Manduca sexta (Lepidoptera, Sphingidae) and its natural host Nicotiana attenuata. IV. Insect-induced ethylene reduces jasmonate-induced nicotine accumulation by regulating putrescine N-methyltransferase transcripts. Plant Physiol 125:2189–2202PubMedCrossRefGoogle Scholar
  170. Wubben MJ 2nd, Su H, Rodermel SR, Baum TJ. 2001. Susceptibility to the sugar beet cyst nematode is modulated by ethylene signal transduction in Arabidopsis thaliana. Mol Plant Microbe Interact 14:1206–1212PubMedCrossRefGoogle Scholar
  171. Wubben MJ 2nd, Rodermel SR, Baum TJ. 2004. Mutation of a UDP-glucose-4-epimerase alters nematode susceptibility and ethylene responses in Arabidopsis roots. Plant J 40:712–724PubMedCrossRefGoogle Scholar
  172. Xu Y, Chang P, Liu D, Narasimhan ML, Raghothama KG, et al. 1994. Plant defense genes are synergistically induced by ethylene and methyl jasmonate. Plant Cell 6:1077–1085PubMedCrossRefGoogle Scholar
  173. Xu P, Narasimhan ML, Samson T, Coca MA, Huh GH, et al. 1998. A nitrilase-like protein interacts with GCC box DNA-binding proteins involved in ethylene and defense responses. Plant Physiol 118:867–874PubMedCrossRefGoogle Scholar
  174. Xu X, Hu X, Neill SJ, Fang J, Cai W. 2005. Fungal elicitor induces singlet oxygen generation, ethylene release and saponin synthesis in cultured cells of Panax ginseng C. A. Meyer. Plant Cell Physiol 46:947–954PubMedCrossRefGoogle Scholar
  175. Yamagami T, Tsuchisaka A, Yamada K, Haddon WF, Harden LA, et al. 2003. Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family. J Biol Chem 278:49102–49112PubMedCrossRefGoogle Scholar
  176. Yamamoto S, Suzuki K, Shinshi H. 1999. Elicitor-responsive, ethylene-independent activation of GCC box-mediated transcription that is regulated by both protein phosphorylation and dephosphorylation in cultured tobacco cells. Plant J 20:571–579PubMedCrossRefGoogle Scholar
  177. Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, et al. 2005. Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3. J Mol Biol 348:253–264PubMedCrossRefGoogle Scholar
  178. Yang Z, Tian L, Latoszek-Green M, Brown D, Wu K. 2005. Arabidopsis ERF4 is a transcriptional repressor capable of modulating ethylene and abscisic acid responses. Plant Mol Biol 58:585–596PubMedCrossRefGoogle Scholar
  179. Yoshida H, Wang KL, Chang CM, Mori K, Uchida E, et al. 2006. The ACC synthase TOE sequence is required for interaction with ETO1 family proteins and destabilization of target proteins. Plant Mol Biol 62:427–437PubMedCrossRefGoogle Scholar
  180. Zhao J, Zheng SH, Fujita K, Sakai K. 2004. Jasmonate and ethylene signalling and their interaction are integral parts of the elicitor signalling pathway leading to beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. J Exp Bot 55:1003–1012PubMedCrossRefGoogle Scholar
  181. Zhao J, Davis LC, Verpoorte R. 2005. Elicitor signal transduction leading to production of plant secondary metabolites. Biotechnol Adv 23:283–333PubMedCrossRefGoogle Scholar
  182. Zhou J, Tang X, Martin GB. 1997. The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes. EMBO J 16:3207–3218PubMedCrossRefGoogle Scholar
  183. Zhou C, Zhang L, Duan J, Miki B, Wu K. 2005. HISTONE DEACETYLASE19 is involved in jasmonic acid and ethylene signaling of pathogen response in Arabidopsis. Plant Cell 17:1196–1204PubMedCrossRefGoogle Scholar
  184. Zhu-Salzman K, Salzman RA, Koiwa H, Murdock LL, Bressan RA, et al. 1998. Ethylene negatively regulates local expression of plant defense lectin genes. Physiol Plant 104:365–372CrossRefGoogle Scholar
  185. Zimmermann P, Hirsch-Hoffmann M, Hennig L, Gruissem W. 2004. GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox. Plant Physiol 136:2621–2632PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Bruce Adie
    • 1
  • José Manuel Chico
    • 1
  • Ignacio Rubio-Somoza
    • 1
  • Roberto Solano
    • 1
  1. 1.Departamento de Genética Molecular de PlantasCentro Nacional de Biotecnología-CSICMadridSpain

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