Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris

  • Minqing Tian (田敏卿)
  • Haofu Dai (戴好富)
  • Xiaoming Li (李晓明)Email author
  • Bingui Wang (王斌贵)Email author


Twenty-four compounds including eight steroids (1–8), nine triterpenoids (9–16, 24), three flavonoids (20–22), and four benzenecarboxylic derivatives (17–19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4–20 and 22–24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3′,4′,5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 μg/mL, while oleanolic acid (14), 3,3′-di-O-methyl ether ellagic acid (18), and 3,3′,4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.


mangrove Sonneratia caseolaris chemical constituents cytotoxic assay 


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Copyright information

© Chinese Society for Oceanology and Limnology, Science Press and Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Minqing Tian (田敏卿)
    • 1
    • 3
  • Haofu Dai (戴好富)
    • 2
  • Xiaoming Li (李晓明)
    • 1
    Email author
  • Bingui Wang (王斌贵)
    • 1
    Email author
  1. 1.Key Laboratory of Experimental Marine Biology, Institute of OceanologyChinese Academy of SciencesQingdaoChina
  2. 2.State Key Laboratory of Tropical Crops Biotechnology, Institute of Tropical Bioscience and BiotechnologyChinese Academy of Tropical Agriculture SciencesHaikouChina
  3. 3.Graduate School of Chinese Academy of SciencesBeijingChina

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