Applied Physics B

, Volume 78, Issue 6, pp 705–709

Multiple-spot optical tweezers created with microlens arrays fabricated by proton beam writing

  • C.H. Sow
  • A.A. Bettiol
  • Y.Y.G. Lee
  • F.C. Cheong
  • C.T. Lim
  • F. Watt
Article

Abstract

We report two different applications for using arrays of microlenses on glass substrate to facilitate multiple-spot optical trapping of colloidal microbeads. The array of microlenses was made of SU8 or PMMA resist and created by a combination of Proton-Beam writing followed by thermal reflow processes. Firstly, similar to previous reports [8, 9, 10 ], the lenses were utilized as an optical element in generating multiple laser spot arrays that were subsequently focused down to impose a microbead array. In addition, we demonstrated the feasibility of a novel approach of integrating the microlens array into a sample chamber to provide localized optical trapping.

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References

  1. 1.
    A. Ashkin: Phys. Rev. Lett. 24, 156 (1970) ADSCrossRefGoogle Scholar
  2. 2.
    A. Ashkin, J.M. Dziedzic, J.E. Bjorkholm, S. Chu: Opt. Lett. 11, 288 (1986) ADSCrossRefGoogle Scholar
  3. 3.
    A. Ashkin, J.M. Dziedzic: Science 235, 1517 (1987) ADSCrossRefGoogle Scholar
  4. 4.
    G. Bao, S. Suresh: Nature Mater. 2, 715 (2003) ADSCrossRefGoogle Scholar
  5. 5.
    K. Svoboda, S.M. Block: Annu. Rev. Biophys. Biomol. Struct. 23, 247 (1994) CrossRefGoogle Scholar
  6. 6.
    M.P. Sheetz (Ed.): Laser Tweezers in Cell Biology (Academic Press 1998) Google Scholar
  7. 7.
    D.G. Grier: Nature 424, 810 (2003) ADSCrossRefGoogle Scholar
  8. 8.
    E.R. Dufresne, G.C. Spalding, M.T. Dearing, S.A. Sheets, D.G. Grier: Rev. Sci. Instrum. 72, 1810 (2001) ADSCrossRefGoogle Scholar
  9. 9.
    P. Korda, M.B. Taylor, D.G. Grier: Phys. Rev. Lett. 89, 128301-1 (2002) ADSCrossRefGoogle Scholar
  10. 10.
    E.R. Dufresne, D.G. Grier: Rev. Sci. Instrum. 69, 1974 (1998) ADSCrossRefGoogle Scholar
  11. 11.
    K. Visscher, G.J. Brakenhoff, J.J. Krol: Cytometry 14(2), 105 (1993) CrossRefGoogle Scholar
  12. 12.
    K. Visscher, S.P. Gross, S.M. Block: IEEE J. Sel. Top. Quantum Electron. 2, 1066 (1996) CrossRefGoogle Scholar
  13. 13.
    J.P. Hoogenboom, D.L.J. Vossen, C. Faivre-Moskalenko, M. Dogterom, A. van Blaaderen: Appl. Phys. Lett. 80(25), 4828 (2002) CrossRefGoogle Scholar
  14. 14.
    F. Watt, J.A. van Kan, T. Osipowicz: MRS Bulletin 25, 33 (2000) Google Scholar
  15. 15.
    D. Daly, R.F. Stevens, M.C. Hutley, N. Davies: Meas. Sci. Technol 1, 759 (1990); N. Borrelli: Micro-optics Technology (Marcel Dekker Inc., New York 1999) ADSCrossRefGoogle Scholar
  16. 16.
    Y. Ogura, K. Kagawa, J. Tanida: Appl. Opt. 40, 5430 (2001) ADSCrossRefGoogle Scholar
  17. 17.
    Video clips of the colloidal assembly using the multiple-spots laser tweezing, rotation of colloidal spheres array and on-board multiple spots optical tweezers trapping can be found from the following website http://www.physics.nus.edu.sg/∼physowch/multi_optw/multi_optw.htmlGoogle Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • C.H. Sow
    • 1
  • A.A. Bettiol
    • 1
    • 2
  • Y.Y.G. Lee
    • 3
  • F.C. Cheong
    • 1
  • C.T. Lim
    • 3
    • 4
  • F. Watt
    • 1
    • 2
  1. 1.Department of Physics, Blk S12, Faculty of ScienceNational University of SingaporeSingapore
  2. 2.Centre for Ion Beam Applications, Department of PhysicsNational University of SingaporeSingapore
  3. 3.Department of Mechanical Engineering, Faculty of EngineeringNational University of SingaporeSingapore
  4. 4.Division of Bioengineering, Faculty of EngineeringNational University of SingaporeSingapore

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