Applied Physics A

, 124:869 | Cite as

Reusable surface-enhanced Raman substrates using microwave annealing

  • V. M. Papadakis
  • G. KenanakisEmail author


In this work, we report the fabrication of large-scale homogeneous surface-enhanced Raman scattering (SERS) substrates using a microwave annealing (MWA) process on Ag thin films on silicon, using a typical low-cost domestic microwave oven, avoiding the use of chemicals and stabilizing agents, or time-consuming and expensive approaches. We provide evidence that in 5–15 s, uniform and reproducible SERS substrates of several centimeter squares can be grown, providing a Raman signal enhancement of five orders of magnitude, for an incident Raman laser with an intensity as low as ~ 0.035 mW, against the characterization of Rhodamine 6G, which is a standard test molecule for SERS. Moreover, we tested the reusability of the fabricated MWA SERS substrates under conditions as tough as ultrasonic sonication in isopropyl alcohol and acetone for 15 min, respectively, and we demonstrate that our SERS substrates can be efficiently reused for more than six times after sonication, which is quite critical since it minimizes the cost of the procedure to minimum.



This work was supported by the European Research Council under ERC advanced grant no. 320081 (PHOTOMETA). Author V.P. acknowledges the financial support of the Stavros Niarchos Foundation within the framework of the project ARCHERS (“Advancing Young Researchers’ Human Capital in Cutting Edge Technologies in the field of Systems Biology Approaches and Personal Genomics for Health and Disease Treatment”). The authors would also like to thank Ms. Manousaki Aleka, for her help in the SEM measurements.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Molecular Biology and BiotechnologyFoundation for Research and Technology-HellasHeraklionGreece
  2. 2.Institute of Electronic Structure and LaserFoundation for Research and Technology-HellasHeraklionGreece

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