Advertisement

Mammalian Genome

, Volume 11, Issue 4, pp 288–291 | Cite as

Silencing of the Y-chromosomal gene tspy during murine evolution

  • Stephanie  Schubert
  • Frank  Dechend
  • Britta  Skawran
  • Bärbel  Kunze
  • Heinz  Winking
  • Carsten  Weile
  • Irmgard  Römer
  • Myriam  Hemberger
  • Reinald  Fundele
  • Tikaram  Sharma
  • Jörg  Schmidtke

Abstract.

We have studied the process of tspy gene silencing in murine evolution. We have isolated functional tspy sequences from Apodemus agrarius, A. sylvaticus, A. flavicollis, and Mus platythrix (subgenus Pyromys) and nonfunctional tspy sequences from species of the subgenus Mus. We present two alternative models as to how tspy may have lost its function in the murine lineage.

Keywords

Alternative Model Gene Silence Murine Evolution Murine Lineage Gene Tspy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag New York Inc. 2000

Authors and Affiliations

  • Stephanie  Schubert
    • 1
  • Frank  Dechend
    • 1
  • Britta  Skawran
    • 1
  • Bärbel  Kunze
    • 2
  • Heinz  Winking
    • 2
  • Carsten  Weile
    • 3
  • Irmgard  Römer
    • 4
  • Myriam  Hemberger
    • 4
  • Reinald  Fundele
    • 4
  • Tikaram  Sharma
    • 5
  • Jörg  Schmidtke
    • 1
  1. 1.Institut für Humangenetik, Medizinische Hochschule, Hannover, D-30625 Hannover, GermanyDE
  2. 2.Institut für Biologie, Medizinische Universität Lübeck, GermanyDE
  3. 3.Institut füt Wildtierbiologie, Tierärztliche Hochschule, Hannover, GermanyDE
  4. 4.Max-Planck-Institut für molekulare Genetik (MPIMG), Berlin-Dahlem, GermanyDE
  5. 5.Department of Zoology, Banaras Hindu University, IndiaIN

Personalised recommendations