Mammalian Genome

, Volume 22, Issue 1–2, pp 1–5 | Cite as

How host defense is encoded in the mammalian genome

  • Bruce BeutlerEmail author
  • Christopher C. GoodnowEmail author


This issue of Mammalian Genome explores the genetic approach to infectious disease susceptibility as it has been applied in mammals. Although no single issue of any journal could give comprehensive treatment to a field so extensive and rapidly growing as this one, these texts describe key discoveries that provided new understanding of immune responses. Classical genetic studies opened and continue to pave the way to deep understanding of many issues in immunology.


Natural Killer Cell Innate Immune System Host Resistance Selective Sweep Autoinflammatory Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of GeneticsThe Scripps Research InstituteLa JollaUSA
  2. 2.John Curtin School of Medical ResearchThe Australian National UniversityCanberra CityAustralia

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