Advertisement

Mammalian Genome

, Volume 21, Issue 5–6, pp 224–230 | Cite as

Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies

  • Marko Milisavljevic
  • Taryn Hearty
  • Tony Y. T. Wong
  • Elodie Portales-Casamar
  • Elizabeth M. Simpson
  • Wyeth W. Wasserman
Article

Abstract

Laboratory Animal Management Assistant (LAMA) is an internet-based system for tracking large laboratory mouse colonies. It has a user-friendly interface with powerful search capabilities that ease day-to-day tasks such as tracking breeding cages and weaning litters. LAMA was originally developed to manage hundreds of new mouse strains generated by a large functional genomics program, the Pleiades Promoter Project (http://www.pleiades.org). The software system has proven to be highly flexible, suitable for diverse management approaches to mouse colonies. It allows custom tagging and grouping of animals, simplifying project-specific handling and access to data. Finally, LAMA was developed in close collaboration with mouse technicians to ease the transition from paper- or Excel-based management systems to computerized tracking, allowing data export in a popular spreadsheet format and automatic printing of cage cards. LAMA is an open-access software tool, freely available to the research community at http://launchpad.net/mousedb.

Keywords

Mouse Coloni Laboratory Information Management System Spreadsheet Format Manual Entry Breeding Cage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

We thank Tammy Philippo and Dora Pak for administrative support. This work was funded by Genome Canada, Genome British Columbia, GlaxoSmithKline R&D Ltd., BC Mental Health and Addiction Services, Child & Family Research Institute, UBC Institute of Mental Health, and UBC Office of the Vice President Research. WWW was supported as a New Investigator of the Canadian Institutes of Health Research and as a Scholar of the Michael Smith Foundation for Health Research. EMS was supported by a Canada Research Chair. We acknowledge the support of the Canada Foundation for Innovation for both the Gene Regulation Bioinformatics Laboratory and the Mouse Laboratory of Functional Genomics.

References

  1. Bishop BS, Hanna MG Jr (1968) Computer program for inbred and-or hybrid animal breeding and production colonies. ORNL-TM-2210. ORNL-TM [reports]. U.S, pp 1–145Google Scholar
  2. Boulukos KE, Pognonec P (2001) MICE, a program to track and monitor animals in animal facilities. BMC Genet 2:4CrossRefPubMedGoogle Scholar
  3. Ching KA, Cooke MP, Tarantino LM, Lapp H (2006) Data and animal management software for large-scale phenotype screening. Mamm Genome 17:288–297CrossRefPubMedGoogle Scholar
  4. Hopley R, Zimmer A (2001) MouseBank: a database application for managing transgenic mouse breeding programs. Biotechniques 30:130–132PubMedGoogle Scholar
  5. Maier H, Lengger C, Simic B, Fuchs H, Gailus-Durner V et al (2008) MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects. BMC Bioinformatics 9:169CrossRefPubMedGoogle Scholar
  6. McKie MA, Webb S (1999) LAMS(TM)—a laboratory animal management system. Mamm Genome 10:349–351CrossRefPubMedGoogle Scholar
  7. Montoliu L (2003) Simple databases to monitor the generation and organisation of transgenic mouse colonies. Transgenic Res 12:251–253CrossRefPubMedGoogle Scholar
  8. Pargent W, Heffner S, Schable KF, Soewarto D, Fuchs H et al (2000) MouseNet database: digital management of a large-scale mutagenesis project. Mamm Genome 11:590–593CrossRefPubMedGoogle Scholar
  9. Silver LM (1993) Recordkeeping and database analysis of breeding colonies. Methods Enzymol 225:3–15CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Marko Milisavljevic
    • 1
  • Taryn Hearty
    • 1
  • Tony Y. T. Wong
    • 1
  • Elodie Portales-Casamar
    • 1
  • Elizabeth M. Simpson
    • 1
    • 2
    • 3
  • Wyeth W. Wasserman
    • 1
    • 2
  1. 1.Centre for Molecular Medicine and Therapeutics at the Child & Family Research InstituteUniversity of British ColumbiaVancouverCanada
  2. 2.Department of Medical GeneticsUniversity of British ColumbiaVancouverCanada
  3. 3.Department of PsychiatryUniversity of British ColumbiaVancouverCanada

Personalised recommendations