Mammalian Genome

, Volume 19, Issue 6, pp 379–381

The Collaborative Cross, developing a resource for mammalian systems genetics: A status report of the Wellcome Trust cohort

Article

Abstract

We report on the progress of a project funded by the Wellcome Trust to produce over 100 recombinant inbred mouse lines as part of the Collaborative Cross (CC) genetic reference panel. These new strains of mice are being derived from a set of eight genetically diverse founders. The genomes of the finished strains will be mosaics of the founder strains’ genomes with a high density of independent recombination breakpoints. The CC mice will be available for distribution free of any intellectual property constraints to serve as a community resource for systems genetics studies.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  1. 1.Department of Human Microbiology, Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael
  2. 2.The Jackson LaboratoryBar HarborUSA
  3. 3.Wellcome Trust Centre for Human GeneticsUniversity of OxfordOxfordUK

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