On growth, fatness, and form: A further look at porcine Chromosome 4 in an Iberian × Landrace cross
A crossed population between Iberian × Landrace pigs consisting of 321 F2, 87 F3, and 85 backcross individuals has been analyzed to refine the number and positions of quantitative trait loci (QTL) affecting shape, growth, fatness, and meat quality traits in SSC4. A multitrait multi-QTL approach has been used. Our results suggest that carcass length and shoulder weight are affected by two loci. The first one, close to the AFABP gene, has a very strong pleiotropic effect on fatness, whereas the second one, in the interval between S0073 and S0214, also affects live weight, although to a lesser extent. This latter QTL would correspond to the FAT1 locus described initially in pigs. It seems that SSC4’s loci play an important role in redistributing total weight, and the Landrace allele increases shoulder weight and carcass length much more than ham or total weight. Furthermore, there is also strong evidence of additional loci influencing pH and color in more distant, telomeric positions.
KeywordsQuantitative Trait Locus Quantitative Trait Locus Effect Carcass Trait Quantitative Trait Locus Position Quantitative Trait Locus Study
This project was funded by Ministerio de Ciencia y Tecnologia (MCYT) (AGF99−0284-CO2) and (CPE03-010) grants. A. Mercadé was funded by a Formació Personal Investigador (FI) fellowship from the Generalitat de Catalunya, and J. Estellé was funded by a Formación Personal Universitario (FPU) grant from the Spanish Ministry of Education and Science (MEC). Part of the analyses was carried out in the Centre de Supercomputació de Catalunya (CESCA).
- Ausubel F, Brent R, Kingston R, Moore D, Seidman J, et al. (1987) Current protocols in molecular biology. (New York: Greene Publishing Associates and Wiley-Interscience)Google Scholar
- Bidanel JP, Rothschild M (2002) Current status of quantitative trait locus mapping in pigs. Pig News and Information 23, 39–54Google Scholar
- Green P, Falls K, Crooks S (1990) Documentation for CRIMAP. Unpublished mimeo. Available at: http ://biobase.dk/Embnetut/Crimap/Google Scholar
- Iannuccelli N, Woloszyn N, Arhainx J, Gellin J, Milan D (1996) GEMMA: a database to manage and automate microsatellite genotyping. In Proceeding of the International Society of Animal Genetics Conference, Tours, France. (Oxford, UK: Blackwell) p 88Google Scholar