European Radiology

, Volume 12, Issue 2, pp 401–408

Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal femur in the prediction of osteoporotic spine fractures

  • Thomas M. Link
  • Volker Vieth
  • Julia Matheis
  • David Newitt
  • Ying Lu
  • Ernst J. Rummeny
  • Sharmila Majumdar
Musculoskeletal

DOI: 10.1007/s003300101127

Cite this article as:
Link, T.M., Vieth, V., Matheis, J. et al. Eur Radiol (2002) 12: 401. doi:10.1007/s003300101127

Abstract.

The aim of this study was to compare structure measures obtained from high-resolution MR images of the calcaneus and the distal radius with bone mineral density (BMD) of the spine and hip in the prediction of osteoporotic spine fracture status. High-resolution MR images of the calcaneus and radius were obtained in 24 post-menopausal women with spine fractures and 22 age-matched controls. Imaging was performed at 1.5 T using a T1-weighted spin-echo sequence (slice thickness 1 mm, in-plane spatial resolution 195×195 µm2). Structure analysis was performed using parameters analogous to standard histomorphometry. Bone mineral density of the spine was obtained using quantitative CT and of the hip with dual-energy X-ray absorptiometry. Significant differences between both patient groups were obtained with BMD and all structure parameters (p<0.05). Using receiver operating characteristic analysis to determine the diagnostic performance in differentiating both groups, the best results were found for BMD of the spine, one of the radial structure measures and a combination of the calcaneal structure measures. In this study BMD of the spine and structure measures of the distal radius were best suited to predict the osteoporotic fracture status of the spine. A combination of BMD and structure measures did not yield any additional information on fracture status.

Osteoporosis BMD MRI High-resolution Spine fractures Calcaneus Distal radius 

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Thomas M. Link
    • 1
  • Volker Vieth
    • 1
  • Julia Matheis
    • 1
  • David Newitt
    • 3
  • Ying Lu
    • 3
  • Ernst J. Rummeny
    • 2
  • Sharmila Majumdar
    • 3
  1. 1.Department of Clinical Radiology, University of Muenster, 48129 Muenster, GermanyGermany
  2. 2.Department of Diagnostic Radiology, Technical University Munich, Ismaninger Strasse 22, 81675 Munich, GermanyGermany
  3. 3.Department of Radiology, University of California, San Francisco, CA 94143, USAUSA

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