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European Radiology

, Volume 8, Issue 6, pp 1009–1113 | Cite as

Pulmonary Wegener's granulomatosis: changes at follow-up CT

  • P. Attali
  • R. Begum
  • H. Ban Romdhane
  • D. Valeyre
  • L. Guillevin
  • M. W. Brauner
Original article, Chest radiology

Abstract.

The objective of this study was to assess the reversibility of pulmonary lesions in Wegener's granulomatosis using serial CT. We reviewed the follow-up CT scans of ten treated patients with confirmed Wegener's granulomatosis. The delay between the first evaluation before treatment and the second, on patients in clinical and biological remission, ranged from 6 to 54 months (mean 20.5 months). Follow-up CT showed a decrease in the extent of disease in all cases. Lesions disappeared completely, without scarring, in 4 of 4 ground-glass opacities, 25 of 36 nodules, and 4 of 9 pulmonary consolidations; they disappeared with residual scarring in 8 of 8 masses, 3 of 9 pulmonary consolidations, and 2 of 36 nodules. The majority of lesions disappear without scarring. Residual fibrosis may follow the occurence of masses and pulmonary consolidation. Computed tomography permits assessment of cicatricial lesions.

Key words: Wegener's granulomatosis Lung diseases CT 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • P. Attali
    • 1
  • R. Begum
    • 1
  • H. Ban Romdhane
    • 1
  • D. Valeyre
    • 2
  • L. Guillevin
    • 3
  • M. W. Brauner
    • 1
  1. 1.Department of Radiology, Hôpital Avicenne, Université Paris XIII,125 route de Stalingrad, F-93 009 Bobigny Cedex, FranceFR
  2. 2.Department of Pneumology, Hôpital Avicenne, Université Paris XIII,125 route de Stalingrad, F-93 009 Bobigny Cedex, FranceFR
  3. 3.Department of Internal Medicine, Hôpital Avicenne, Université Paris XIII,125 route de Stalingrad, F-93 009 Bobigny Cedex, FranceFR

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