European Radiology

, Volume 28, Issue 2, pp 780–787 | Cite as

Comparison between free-breathing radial VIBE on 3-T MRI and endoscopic ultrasound for preoperative T staging of resectable oesophageal cancer, with histopathological correlation

  • Jinrong Qu
  • Hongkai Zhang
  • Zhaoqi Wang
  • Fengguang Zhang
  • Hui Liu
  • Zhidan Ding
  • Yin Li
  • Jie Ma
  • Zhongxian Zhang
  • Shouning Zhang
  • Yafeng Dong
  • Lina Jiang
  • Wei Zhang
  • Robert Grimm
  • Berthold Kiefer
  • Ihab R. Kamel
  • Jianjun Qin
  • Hailiang Li
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Abstract

Objectives

To compare the T staging of resectable oesophageal cancer (OC) using radial VIBE (r-VIBE) and endoscopic ultrasound (EUS) with pathological confirmation of the T stage.

Methods

Forty-three patients with endoscopically proven OC and indeterminate T1/T2/T3/T4a stage by computed tomography (CT) and EUS were imaged on a 3-T magnetic resonance imaging (MRI) scanner. T stage was scored on MRI and EUS by two independent radiologists and one endoscopist, respectively, and compared with postoperative pathological findings. T staging agreement between r-VIBE and EUS with postoperative pathological T staging was analysed by a kappa test.

Results

EUS and pathological T staging showed agreement of 69.8% (30/43). Radial VIBE and pathological T staging agreement was 86.0% (37/43) and 90.7% (39/43) for readers 1 and 2, respectively. High accuracy for T1/T2 stage was obtained for both r-VIBE readers (90.5% and 100% for reader 1 and reader 2, respectively) and EUS reader (100%). For T3/T4, r-VIBE showed accuracy of 81.8% and 90.9% for reader 1 and reader 2, respectively, while for EUS, accuracy was only 68.2% compared with pathological T staging.

Conclusions

Contrast-enhanced r-VIBE is comparable to EUS in T staging of resectable OC with stage of T1/T2, and is superior to EUS in staging of T3/T4 lesions.

Key Points

• Radial VIBE may be useful in preoperative T staging of OC

• Accuracy of staging on r-VIBE is higher in T1/2 than in T3/4

• Accuracy of EUS was 100% and 68.2% for T1/T2 and T3/T4 stage

• Inter-reader agreement of T staging for r-VIBE was good

Keywords

Oesophageal cancer Tumour staging Radial VIBE Free-breathing Endoscopic ultrasonography 
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Notes

Compliance with ethical standards

Guarantor

The scientific guarantor of this publication is Hailiang Li.

Starting from the study concept and design to manuscript preparation Jianjun Qin and Hailiang Li contributed equally to >70% of the total work towards the successful completion of this project. Hence it is justified that they both deserve the corresponding authorship in this paper, which is approved by the rest of the team.

Conflict of interest

The authors of this manuscript declare relationships with the following companies: Siemens. Three authors from Siemens provided the prototype sequence for free and reviewed the paper without any conflict of interest.

Funding

This study has received funding by special funding of the Henan Health Science and Technology Innovation Talent Project (No. 201004057).

Statistics and biometry

No complex statistical methods were necessary for this paper.

Informed consent

Written informed consent was waived by the Institutional Review Board.

Ethical approval

Institutional Review Board approval was obtained.

Study subjects or cohorts overlap

Part of the study subjects or cohorts have been used in previously reports in 2016 and 2017 ISMRM (Jinrong Qu, Hui Liu, Zhaoqi Wang, Ihab R Kamel, Kiefer Berthold, Robert Grimm, Jianjun Qin, Hailiang Li. A comparison between free-breathing radial VIBE in 3T MR and endoscopic ultrasound for preoperative T staging of potentially resectable esophageal cancer with histopathological correlation.2016 ISMRM. Abstract ID: 3690 and Jinrong Qu, Hongkai Zhang, Hui Liu, Xu Yan, Zhaoqi Wang, Kiefer Berthold, Nickel Marcel Dominik, Ihab R. Kamel, Hailiang Li. Preoperative T Staging of Potentially Resectable Esophageal Cancer: 3T MRI based on T2-TSE-BLADE and contrast-enhanced free-breathing radial VIBE (StarVIBE) vs endoscopic ultrasound. 2017 ISMRM. Abstract ID: 4373) and 2016 RSNA (Zhaoqi Wang,Hui liu, Hongkai Zhang, Jinrong Qu. A Comparison Between 3.0T MRI and Histopathology for Preoperative T Staging of Potentially Resectable Esophageal Cancer. 2016 RSNA. Abstract ID: 16015158). However, it is small sample for both them. Now we added more cases in this paper, and riched the analysis.

Methodology

• retrospective

• case-control study

• performed at one institution

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Copyright information

© European Society of Radiology 2017

Authors and Affiliations

  • Jinrong Qu
    • 1
  • Hongkai Zhang
    • 1
  • Zhaoqi Wang
    • 1
  • Fengguang Zhang
    • 1
  • Hui Liu
    • 2
  • Zhidan Ding
    • 3
  • Yin Li
    • 3
  • Jie Ma
    • 4
  • Zhongxian Zhang
    • 4
  • Shouning Zhang
    • 1
  • Yafeng Dong
    • 1
  • Lina Jiang
    • 1
  • Wei Zhang
    • 5
  • Robert Grimm
    • 6
  • Berthold Kiefer
    • 6
  • Ihab R. Kamel
    • 7
  • Jianjun Qin
    • 3
  • Hailiang Li
    • 1
  1. 1.Department of RadiologyAffiliated Cancer Hospital of Zhengzhou University, Henan Cancer HospitalZhengzhouChina
  2. 2.NEA MR CollaborationSiemens Ltd., ChinaShanghaiChina
  3. 3.Department of Thoracic surgeryAffiliated Cancer Hospital of Zhengzhou University, Henan Cancer HospitalZhengzhouChina
  4. 4.Department of PathologyAffiliated Cancer Hospital of Zhengzhou University, Henan Cancer HospitalZhengzhouChina
  5. 5.Department of Endoscopic UltrasoundAffiliated Cancer Hospital of Zhengzhou University, Henan Cancer HospitalZhengzhouChina
  6. 6.MR-PredevelopmentSiemens Healthcare GmbHErlangenGermany
  7. 7.Department of RadiologyJohns Hopkins University School of MedicineBaltimoreUSA

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