Evaluation of percutaneous biopsies of renal masses under MRI-guidance: a retrospective study about 26 cases
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To determine whether MRI allows safe and accurate guidance for biopsies of renal masses.
Materials and methods
Between May 2010 and September 2013, 26 patients (15 men and 11 women) with 26 renal masses underwent MRI-guided percutaneous biopsy. For each patient, we retrospectively collected the epidemiological, procedural and histopathological data.
Mean size of tumour was 3.6 cm (range 0.6 – 9 cm). Mean procedure time was 48 minutes (range 37 – 70 min). Malignancy was found in the percutaneous samples in 81 % (21/26) of the masses. All these cases were considered as true positive biopsies. Benignity was found in the percutaneous samples in 5/26 (19 %) of the masses but was confirmed only in 3 cases. The other 2 cases included one false negative case and one undetermined biopsy, as patient was lost to follow-up. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of this study were 95.4 %, 100 %, 100 %, 75 % and 96 %, respectively
MRI-guidance is safe and accurate to target renal masses.
• Percutaneous interventions can be performed with MRI-guidance
• MRI offers real-time multiplanar imaging capabilities without radiation
• MRI-guidance allows to target renal tumours
KeywordsPercutaneous biopsy Renal masses Interventional MRI Real-time guidance MRI guidance
magnetic resonance imaging
cone beam computed tomography
small renal masses
negative predictive value
positive predictive value
Authors would like to thank Marion VAZEL for her help in coordinating the clinical study.
The scientific guarantor of this publication is Afshin Gangi. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. This study has received funding by French state funds managed by the ANR within the Investissements d'Avenir programme (Labex CAMI) under reference ANR-11-LABX-0004. No complex statistical methods were necessary for this paper. Institutional Review Board approval was obtained. Written informed consent was obtained from all subjects (patients) in this study. Methodology: retrospective, observational, performed at one institution.