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European Radiology

, Volume 23, Issue 11, pp 3213–3218 | Cite as

Novel connecting tube for saline chaser in contrast-enhanced CT: the effect of spiral flow of saline on contrast enhancement

  • Masafumi KidohEmail author
  • Takeshi Nakaura
  • Kazuo Awai
  • Koji Yuba
  • Takayuki Kobayashi
  • Young-Kwang Park
  • Takanobu Yagi
  • Kazunori Harada
  • Yasuyuki Yamashita
Contrast Media

Abstract

Objective

To evaluate the effect of a newly developed connecting tube, which generates a spiral flow of saline, on aortic and hepatic contrast enhancement during hepatic-arterial phase (HAP) and portal venous phase (PVP) computed tomography (CT).

Methods

Eighty patients were randomly assigned to one of two protocols: with a new or a conventional tube. The contrast material (600 mgI/kg) was delivered over 30 s; this was followed by the administration of 25 ml saline solution delivered at the same injection rate as the contrast material. Unenhanced and contrast-enhanced CT images of the upper abdomen were obtained. We calculated the changes in the CT number (∆HU) for the aorta during HAP and PVP, and for the liver during PVP. We compared ∆HU between protocols.

Results

The mean ∆HU for the abdominal aorta during HAP was significantly higher with the new tube protocol than with the conventional tube protocol (322 ± 53 vs. 290 ± 53, P < 0.01). There were no significant differences in the mean ∆HU for the abdominal aorta and liver during PVP between the two protocols (P > 0.05).

Conclusion

The new connecting tube increased the effect of a saline chaser and significantly improved aortic enhancement during HAP.

Key Points

• Optimal administration of intravenous contrast material is essential for optimal CT quality.

• A new connecting tube can generate spiral flow, which improves intravenous administration.

• The new connecting tube improved aortic contrast enhancement during the hepatic-arterial phase.

• The new connecting tube increased the effect of a saline chaser.

Keywords

Contrast-enhanced CT Saline chaser Contrast medium Contrast enhancement Spiral flow 

Notes

Acknowledgements

There was no direct financial support from industry for this study. This study received the connecting tube from Nemoto-Kyorindo, Tokyo, Japan, the manufacturer of the connecting tube used in this study. K.Y. is an employee of Nemoto-Kyorindo. Y.P. is chief executive officer of EBM, Tokyo, Japan. Y.P. and T.Y have pending and/or awarded patents for the subject matter described in the manuscript and receive royalty income for a patent license from Nemoto-Kyorindo. The authors (M.K, T.N, K.A, T.K, K.H, Y.Y) who were not employees of Nemoto-Kyorindo or EBM had control of data and information that might have presented a conflict of interest.

Supplementary material

Movie 1 (Electronic Supplementary Material

An image obtained by actually imaging the pushed state of the contrast agent using the new connecting tube. A black ink was mixed to the contrast agent. The saline flow rate was 4 ml/s. The pushed state was imaged by 500 frames per second using a high-speed camera. The portion appearing black in Movie 1 was the flow of the contrast agent. As understood from Movie 1, the new connecting tube was able to generate the spiral flow (MPG 2948 kb)

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Copyright information

© European Society of Radiology 2013

Authors and Affiliations

  • Masafumi Kidoh
    • 1
    • 2
    Email author
  • Takeshi Nakaura
    • 1
    • 2
  • Kazuo Awai
    • 3
  • Koji Yuba
    • 4
  • Takayuki Kobayashi
    • 5
  • Young-Kwang Park
    • 6
  • Takanobu Yagi
    • 6
  • Kazunori Harada
    • 7
  • Yasuyuki Yamashita
    • 2
  1. 1.Diagnostic RadiologyAmakusa Medical CenterAmakusaJapan
  2. 2.Department of Diagnostic Radiology, Graduate School of Medical SciencesKumamoto University 1-1-1HonjoJapan
  3. 3.Department of Diagnostic RadiologyHiroshima UniversityHiroshimaJapan
  4. 4.Sales Division, Nemoto KyorindoTokyoJapan
  5. 5.Kitasato Institute HospitalTokyoJapan
  6. 6.Faculty of Science and EngineeringWaseda UniversityTokyoJapan
  7. 7.Department of SurgeryAmakusa Medical CenterAmakusaJapan

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