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European Radiology

, Volume 23, Issue 9, pp 2561–2572 | Cite as

Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up

  • Joao Martins Pisco
  • Hugo Rio TintoEmail author
  • Luís Campos Pinheiro
  • Tiago Bilhim
  • Marisa Duarte
  • Lúcia Fernandes
  • José Pereira
  • António G. Oliveira
Interventional

Abstract

Objectives

To evaluate the short- and medium-term results of prostatic arterial embolisation (PAE) for benign prostatic hyperplasia (BPH).

Methods

This was a prospective non-randomised study including 255 patients diagnosed with BPH and moderate to severe lower urinary tract symptoms after failure of medical treatment for at least 6 months. The patients underwent PAE between March 2009 and April 2012. Technical success is when selective prostatic arterial embolisation is completed in at least one pelvic side. Clinical success was defined as improving symptoms and quality of life. Evaluation was performed before PAE and at 1, 3, 6 and every 6 months thereafter with the International Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF), uroflowmetry, prostatic specific antigen (PSA) and volume. Non-spherical polyvinyl alcohol particles were used.

Results

PAE was technically successful in 250 patients (97.9 %). Mean follow-up, in 238 patients, was 10 months (range 1–36). Cumulative rates of clinical success were 81.9 %, 80.7 %, 77.9 %, 75.2 %, 72.0 %, 72.0 %, 72.0 % and 72.0 % at 1, 3, 6, 12, 18, 24, 30 and 36 months, respectively. There was one major complication.

Conclusions

PAE is a procedure with good results for BPH patients with moderate to severe LUTS after failure of medical therapy.

Key Points

Prostatic artery embolisation offers minimally invasive therapy for benign prostatic hyperplasia.

Prostatic artery embolisation is a challenging procedure because of vascular anatomical variations.

PAE is a promising new technique that has shown good results.

Keywords

Benign prostatic hyperplasia Therapeutic embolization Prostatic diseases Angiography Catheterization 

Abbreviations

BPH

benign prostatic hyperplasia

PAE

prostatic artery embolisation

Notes

Conflict of interest

There is no funding or potential conflicts of interest for the authors regarding this article. The corresponding authors confirm that they have full access to all the data in this study and have final responsibility for the decision to submit for publication. All authors had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

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Copyright information

© European Society of Radiology 2012

Authors and Affiliations

  • Joao Martins Pisco
    • 1
  • Hugo Rio Tinto
    • 1
    • 2
    • 3
    Email author
  • Luís Campos Pinheiro
    • 4
    • 5
  • Tiago Bilhim
    • 1
    • 2
    • 3
  • Marisa Duarte
    • 1
  • Lúcia Fernandes
    • 1
    • 2
  • José Pereira
    • 6
    • 7
  • António G. Oliveira
    • 8
  1. 1.Interventional RadiologySaint Louis HospitalLisbonPortugal
  2. 2.Radiology DepartmentHospital de São JoséLisbonPortugal
  3. 3.Radiology Department, Faculdade de Ciências MédicasUniversidade Nova de LisboaLisbonPortugal
  4. 4.Urology DepartmentHospital de São JoséLisbonPortugal
  5. 5.Urology Department, Faculdade de Ciências MédicasUniversidade Nova de LisboaLisbonPortugal
  6. 6.Radiology DepartmentHospital Santo António dos CapuchosLisbonPortugal
  7. 7.Saint Louis HospitalInterventional RadiologyLisbonPortugal
  8. 8.Biostatistics Department, Faculdade de Ciências MédicasUniversidade Nova de LisboaLisbonPortugal

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