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European Radiology

, Volume 21, Issue 6, pp 1153–1159 | Cite as

Tractography of lumbar nerve roots: initial results

  • Vincent BalbiEmail author
  • Jean-François Budzik
  • Alain Duhamel
  • Anne Bera-Louville
  • Vianney Le Thuc
  • Anne Cotten
Musculoskeletal

Abstract

Objectives

The aims of this preliminary study were to demonstrate the feasibility of in vivo diffusion tensor imaging (DTI) and fibre tracking (FT) of the lumbar nerve roots, and to assess potential differences in the DTI parameters of the lumbar nerves between healthy volunteers and patients suffering from disc herniation.

Methods

Nineteen patients with unilateral sciatica related to posterolateral or foraminal disc herniation and 19 healthy volunteers were enrolled in this study. DTI with tractography of the L5 or S1 nerves was performed. Mean fractional anisotropy (FA) and mean diffusivity (MD) values were calculated from tractography images.

Results

FA and MD values could be obtained from DTI-FT images in all controls and patients. The mean FA value of the compressed lumbar nerve roots was significantly lower than the FA of the contralateral nerve roots (p = 0.0001) and of the nerve roots of volunteers (p = 0.0001). MD was significantly higher in compressed nerve roots than in the contralateral nerve root (p = 0.0002) and in the nerve roots of volunteers (p = 0.04).

Conclusion

DTI with tractography of the lumbar nerves is possible. Significant changes in diffusion parameters were found in the compressed lumbar nerves.

Keywords

Echo-planar imaging Magnetic resonance imaging Sciatica DTI Herniated disc 

Notes

Acknowledgment

The authors acknowledge Hélène Tostain for English manuscript corrections.

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Copyright information

© European Society of Radiology 2011

Authors and Affiliations

  • Vincent Balbi
    • 1
    Email author
  • Jean-François Budzik
    • 1
  • Alain Duhamel
    • 2
  • Anne Bera-Louville
    • 3
  • Vianney Le Thuc
    • 1
  • Anne Cotten
    • 1
  1. 1.Service de Radiologie et d’Imagerie musculo-squelettiqueHôpital Roger SalengroLille CedexFrance
  2. 2.Université de Lille 2, UDSLLilleFrance
  3. 3.Hopital Roger SalengroService de RhumatologieLilleFrance

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