European Radiology

, Volume 21, Issue 4, pp 823–831

MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn’s disease

  • Emanuele Casciani
  • Gabriele Masselli
  • Giovanni Di Nardo
  • Elisabetta Polettini
  • Luca Bertini
  • Salvatore Oliva
  • Irene Floriani
  • Salvatore Cucchiara
  • Gianfranco Gualdi
Magnetic Resonance

Abstract

Objective

The aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn’s disease (CD).

Methods

Paediatric patients with suspected CD were considered eligible to be enrolled in the study. All patients underwent diagnostic work-up including 1.5-T MRE, ileo-colonoscopy and oesophagogastroduodenoscopy. SBCE was not performed if MRE showed SB stricture or extra-intestinal findings consistent with symptoms.

Results

Sixty consecutive paediatric patients (36 male; average age 14) were enrolled into the study. A positive diagnosis for CD was made in 19 patients, 29 had a negative result and 12 were affected by other gastro-intestinal conditions. SBCE was performed in 37 patients (61.7%); 23 patients were excluded (strictures in five, extra-intestinal findings in 11 and parents’ refusal in seven cases). The accuracy, sensitivity, and specificity of MRE and SBCE were 98.3%, 100%, 97.6%, and 91.9%, 90.9%, 92.3%, respectively.

Conclusion

Both MRE and SBCE are accurate methods for patients with suspected CD. MRE can be used as a primary imaging technique in suspected CD, in that it allows access to the ileal stricture, which forms a contra-indication for SBCE and provides extra-intestinal information.

Keywords

Children Crohn’s disease MR enterography Small-bowel capsule endoscopy Pediatric patient Small-bowel disease 

Copyright information

© European Society of Radiology 2010

Authors and Affiliations

  • Emanuele Casciani
    • 1
  • Gabriele Masselli
    • 1
  • Giovanni Di Nardo
    • 2
  • Elisabetta Polettini
    • 1
  • Luca Bertini
    • 1
  • Salvatore Oliva
    • 2
  • Irene Floriani
    • 3
  • Salvatore Cucchiara
    • 2
  • Gianfranco Gualdi
    • 1
  1. 1.Radiology DEA, Azienda Policlinico Umberto I“La Sapienza” UniversityRomeItaly
  2. 2.Pediatric Gastroenterology“La Sapienza” UniversityRomeItaly
  3. 3.Istituto di Ricerche Farmacologiche “Mario Negri”MilanItaly

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