European Radiology

, Volume 20, Issue 10, pp 2341–2347 | Cite as

Single breath-hold magnetic resonance cine imaging for fast assessment of global and regional left ventricular function in clinical routine

  • Kai Nassenstein
  • Holger Eberle
  • Stefan Maderwald
  • Christoph J. Jensen
  • Christina Heilmaier
  • Thomas Schlosser
  • Oliver Bruder



To evaluate a TGRAPPA (temporal parallel acquisition technique)-accelerated, single breath-hold multi-slice cine imaging approach for the assessment of left ventricular (LV) function.


One hundred eleven patients were examined at 1.5 T. Cine imaging was performed with single-slice breath-hold acquisitions in short-axis orientation using a SSFP (TR 2.63 ms, TE 1.12 ms, FA 72°) sequence and a TGRAPPA SSFP (TR 2.66 ms, TE 1.11 ms, FA 72°, AF 3) sequence, which covered the entire LV in multiple short-axis slices during a single breath-hold. End-diastolic (EDV), end-systolic (ESV), stroke volumes (SV), ejection fraction (EF), muscle mass (MM) and regional wall motion were assessed for both data sets.


Single breath-hold imaging was feasible in 108 patients. Excellent correlations were observed for all volumetric parameters derived from both data sets (all r > 0.97). While EDV and ESV showed marginally lower values for single breath-hold imaging (EDV: −1.6 ± 7.9 ml; ESV: −1.8 ± 6.0 ml, p < 0.05), no differences were observed for SV, EF, MM and regional wall motion assessment. Single breath-hold imaging required significant shorter acquisition times (28 ± 6 s vs. 335 ± 87 s).


TGRAPPA-accelerated multi-slice SSPF imaging allows for fast and accurate assessment of regional and global LV function within a single breath-hold.


Cine magnetic resonace imaging Parallel imaging TGRAPPA Cardiac volume Left ventricular function 


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Copyright information

© European Society of Radiology 2010

Authors and Affiliations

  • Kai Nassenstein
    • 1
  • Holger Eberle
    • 2
  • Stefan Maderwald
    • 1
    • 3
  • Christoph J. Jensen
    • 2
  • Christina Heilmaier
    • 1
  • Thomas Schlosser
    • 1
  • Oliver Bruder
    • 2
  1. 1.Department of Diagnostic and Interventional Radiology and NeuroradiologyUniversity Hospital EssenEssenGermany
  2. 2.Department of Cardiology and AngiologyElisabeth Hospital EssenEssenGermany
  3. 3.Erwin L. Hahn Institute for Magnetic Resonance ImagingUniversity Duisburg-EssenEssenGermany

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