European Radiology

, Volume 19, Issue 10, pp 2481–2486 | Cite as

Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion-weighted MR imaging

  • Jing Ren
  • Yi HuanEmail author
  • He Wang
  • YaLi Ge
  • YingJuan Chang
  • Hong Yin
  • LiJun Sun
Magnetic Resonance


The aim of this study was to evaluate the usefulness of diffusion-weighted imaging (DWI) in detecting seminal vesicle invasion (SVI). A total of 283 patients underwent conventional MRI and DWI before prostate cancer surgery. The apparent diffusion coefficient (ADC) values of all PCa foci, SVI and seminal vesicle were measured. T2 images alone and then T2 images combined with DWI were scored for the likelihood of SVI. The area under the receiver operating characteristic curve (AUC) was used to assess accuracy. Statistical significance was inferred at P < 0.05. On pathological analysis, 39 patients had SVI. The ADC values of SVI were significantly lower than those of SV. The AUC for T2-weighted imaging plus DW imaging (0.897) was significantly larger (P < 0.05) than that for T2-weighted imaging alone (0.779). T2 images combined with DWI shows significantly higher accuracy than T2-weighted imaging alone in the detection of SVI.


Prostate carcinoma Seminal vesicle Magnetic resonance Diffusion-weighted imaging Apparent diffusion coefficient 


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Copyright information

© European Society of Radiology 2009

Authors and Affiliations

  • Jing Ren
    • 1
  • Yi Huan
    • 1
    Email author
  • He Wang
    • 2
  • YaLi Ge
    • 1
  • YingJuan Chang
    • 1
  • Hong Yin
    • 1
  • LiJun Sun
    • 1
  1. 1.Department of Radiology, Xijing HospitalFourth Military Medical UniversityXi’anPeople’s Republic of China
  2. 2.Department of Urology, Xijing HospitalFourth Military Medical UniversityXi’anPeople’s Republic of China

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