European Radiology

, Volume 19, Issue 8, pp 2024–2032 | Cite as

Node-by-node correlation between MR and PET/CT in patients with uterine cervical cancer: diffusion-weighted imaging versus size-based criteria on T2WI

  • Eugene K. Choi
  • Jeong Kon Kim
  • Hyuck Jae Choi
  • Seong Ho Park
  • Bum-Woo Park
  • Namkug Kim
  • Jae Seung Kim
  • Ki Chun Im
  • Gyunggoo Cho
  • Kyoung-Sik Cho
Magnetic Resonance

Abstract

The purpose of the study was to perform a node-by-node comparison of an ADC-based diagnosis and various size-based criteria on T2-weighted imaging (T2WI) with regard to their correlation with PET/CT findings in patients with uterine cervical cancer. In 163 patients with 339 pelvic lymph nodes (LNs) with short-axis diameter >5 mm, the minimum apparent diffusion coefficient (ADC), mean ADC, short- and long-axis diameters, and ratio of long- to short-axis diameters (L/S ratio) were compared in PET/CT-positive and -negative LNs. On PET/CT, 118 (35%) LNs in 58 patients were positive. The mean value of minimum and mean ADCs, short- and long-axis diameters, and L/S ratio were different in PET/CT-positive (0.6436 × 10−3 mm2/s, 0.756 × 10−3 mm2/s, 10.3 mm, 13.2 mm, 1.32, respectively) and PET/CT-negative LNs (0.8893 × 10−3 mm2/s, 1.019 × 10−3 mm2/s, 7.4 mm, 11.0 mm, 1.49, respectively) (P < 0.05). The Az value of the minimum ADC (0.864) was greater than those of mean ADC (0.836), short-axis diameter (0.764), long-axis diameter (0.640) and L/S ratio (0.652) (P < 0.05). The sensitivity and accuracy of the minimum ADC (86%, 82%) were greater than those of the short-axis diameter (55%, 74%), long-axis diameter (73%, 58%) and L/S ratio (52%, 66%) (P < 0.05). ADC showed superior correlation with PET/CT compared with conventional size-based criteria on T2WI.

Keywords

Diffusion magnetic resonance imaging Lymphatic metastasis Lymph nodes Uterine cervical neoplasms Comparative study 

Notes

Acknowledgements

This work was supported by the Korea Research Foundation Grant funded by a grant of the Korea Healthcare Technology R&D Project, Ministry of Health Welfare, Republic of Korea (A070001) and by the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean government (MOST) (no. R01-2006-000-10998-0)

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Copyright information

© European Society of Radiology 2009

Authors and Affiliations

  • Eugene K. Choi
    • 1
    • 2
  • Jeong Kon Kim
    • 1
  • Hyuck Jae Choi
    • 1
  • Seong Ho Park
    • 1
  • Bum-Woo Park
    • 1
  • Namkug Kim
    • 1
  • Jae Seung Kim
    • 3
  • Ki Chun Im
    • 3
  • Gyunggoo Cho
    • 4
  • Kyoung-Sik Cho
    • 1
  1. 1.Department of Radiology, Asan Medical CenterUniversity of UlsanSeoulKorea
  2. 2.Department of Radiological SciencesDavid Geffen School of Medicine at UCLALos AngelesUSA
  3. 3.Department of Nuclear Medicine, Asan Medical CenterUniversity of UlsanSeoulKorea
  4. 4.Bio-MR centerKorea Basic Science InstituteChungcheongbuk-doKorea

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