European Radiology

, 18:2363

Diagnostic performance of detecting breast cancer on computed radiographic (CR) mammograms: comparison of hard copy film, 3-megapixel liquid-crystal-display (LCD) monitor and 5-megapixel LCD monitor

  • Takayuki Yamada
  • Akihiko Suzuki
  • Nachiko Uchiyama
  • Noriaki Ohuchi
  • Shoki Takahashi


The purpose was to compare observer performance in the detection of breast cancer using hard-copy film, and 3-megapixel (3-MP) and 5-megapixel (5-MP) liquid crystal display (LCD) monitors in a simulated screening setting. We amassed 100 sample sets, including 32 patients with surgically proven breast cancer (masses present, N = 12; microcalcifications, N = 10; other types, N = 10) and 68 normal controls. All the mammograms were obtained using computed radiography (CR; sampling pitch of 50 μm). Twelve mammographers independently assessed CR mammograms presented in random order for hard-copy and soft-copy reading at minimal 4-week intervals. Observers rated the images on seven-point (1 to 7) and continuous (0 to 100) malignancy scales. Receiver-operating-characteristics analysis was performed, and the average area under the curve (AUC) was calculated for each modality. The jackknife method with the Bonferroni correction was applied to multireader/multicase analysis. The average AUC values for the 3-MP LCD, 5-MP LCD, and hard-copy film were 0.954, 0.947, and 0.956 on the seven-point scale and 0.943, 0.923, and 0.944 on the continuous scale, respectively. There were no significant differences among the three modalities on either scale. Soft-copy reading using 3-MP and 5-MP LCDs is comparable to hard-copy reading for detecting breast cancer.


Breast neoplasm Digital radiography Data display Liquid crystals ROC curve 







liquid crystal display


area under the curve


Digital Mammographic Imaging Screening Trial


computed radiography


Breast Imaging Reporting and Data System


Digital Imaging and Communications in Medicine


greyscale standard display function


receiver-operating characteristic


full-field digital mammography


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Copyright information

© European Society of Radiology 2008

Authors and Affiliations

  • Takayuki Yamada
    • 1
  • Akihiko Suzuki
    • 2
  • Nachiko Uchiyama
    • 3
  • Noriaki Ohuchi
    • 2
  • Shoki Takahashi
    • 1
  1. 1.Department of Diagnostic RadiologyTohoku University, Graduate School of MedicineSendaiJapan
  2. 2.Department of Surgical OncologyTohoku University, Graduate School of MedicineSendaiJapan
  3. 3.National Cancer Center, Research Center for Cancer Prevention and ScreeningTokyoJapan

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