European Radiology

, Volume 18, Issue 10, pp 2108–2119 | Cite as

Screening for coronary artery disease in respiratory patients: comparison of single- and dual-source CT in patients with a heart rate above 70 bpm

  • Vittorio Pansini
  • Martine Remy-JardinEmail author
  • Nunzia Tacelli
  • Jean-Baptiste Faivre
  • Thomas Flohr
  • Valérie Deken
  • Alain Duhamel
  • Jacques Remy


To evaluate the assessibility of coronary arteries in respiratory patients with high heart rates. This study was based on the comparative analysis of two paired populations of 54 patients with a heart rate >70 bpm evaluated with dual-source (group 1) and single-source (group 2) CT. The mean heart rate was 89.1 bpm in group 1 and 86.7 bpm in group 2 (P = 0.26). The mean number of assessable segments per patient was significantly higher in group 1 compared to group 2 (P ≤ 0.0001). The proportions of patients in whom proximal and mid-coronary segments were assessable (i.e., the anatomical level enabling screening for asymptomatic coronary artery disease) were 35.3% for heart rates <110 bpm, 35.6% for heart rates <100 bpm, 40% for heart rates <90 bpm, and 60% for heart rates <80 bpm in group 1 and 11.3, 12.2, 8.8, and 10% for the corresponding thresholds in group 2 (P < 0.05). In both groups of patients, coronary artery imaging was obtained from standard CT angiograms of the chest. The improvement in coronary imaging with dual-source CT suggests that high heart rates should no longer be considered as contraindications for ECG-gated CT angiograms of the chest whenever clinically relevant.


Coronary arteries Dual-source CT CT angiography 


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Copyright information

© European Society of Radiology 2008

Authors and Affiliations

  • Vittorio Pansini
    • 1
  • Martine Remy-Jardin
    • 1
    Email author
  • Nunzia Tacelli
    • 1
  • Jean-Baptiste Faivre
    • 1
  • Thomas Flohr
    • 2
  • Valérie Deken
    • 3
  • Alain Duhamel
    • 3
  • Jacques Remy
    • 1
  1. 1.Department of Thoracic Imaging, Hospital CalmetteUniversity Center of LilleLille cedexFrance
  2. 2.Department of Research and DevelopmentSiemens Medical SolutionsForchheimGermany
  3. 3.Department of Medical StatisticsUniversity Center of LilleLilleFrance

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