Multidetector CT angiography in the assessment of peripheral arterial occlusive disease: accuracy in detecting the severity, number, and length of stenoses
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The purpose was to evaluate the accuracy of multidetector CT angiography (MD-CTA) in the morphologic assessment of peripheral arterial occlusive disease (PAOD) compared to digital subtraction angiography (DSA). Fifty consecutive patients referred for DSA of the peripheral arteries due to PAOD were prospectively included in this study and underwent 16-row MD-CTA prior to DSA. Maximum intensity projections and multipath curved planar reformations were created with a semi-automated toolbox. Twenty-one vascular segments were defined in each leg and compared to DSA findings with regard to gradation, length, and number of lesions. Mean sensitivity and specificity in the detection of significant stenoses (over 70%) were 100% and 99.5% in the iliac arteries, 97.4% and 99.0% in the femoro-popliteal arteries, and 98.3% and 99.8% in the infrapopliteal arteries, respectively. High kappa values for exact stenoses gradation (0.74–1), lesion length (0.74–1), and number of lesions (0.71–1) were reached by MD-CTA, indicating high agreement with DSA. Non-invasive MD-CTA is an accurate tool for the assessment of all treatment-relevant morphologic information of PAOD (gradation, length, and number of stenoses) compared to DSA.
KeywordsCT angiography Vascular imaging Peripheral vascular diseases Computer-generated 3D imaging
This work was supported by Fonds zur Förderung der wissenschaftlichen Forschung (FWF, Austria) under the contract no. L291–N04.
- 4.Rubin GD, Schmidt AJ, Logan LJ, Olcott C, Zarins CK, Napel S et al (1999) Multidetector-row CT angiography of lower extremity occlusive disease: a new application for CT scanning. Radiology 210:588Google Scholar
- 11.Fleischmann D, Kanitsar A, Lomoschitz E, Koechl A (2002) Multi-path curved planar reformation of the peripheral arterial tree. Radiology 225:363Google Scholar
- 13.Kanitsar A (2001) Advanced visualzation techniques for vessel investigation [Master Thesis]. Vienna, University of TechnologyGoogle Scholar
- 14.Kanitsar A, Fleischmann D, Wegenkittl R, Felkel P, Groeller E (2002) CPR-curved planar reformation. IEEE Visualization; 2002. IEEE Computer Society, Boston, pp 37–44Google Scholar
- 15.Kanitsar A, Wegenkittl R, Felkel P, Fleischmann D, Sandner D, Groeller E (2001) Computed tomography angiography: a case study of peripheral vessel investigation. IEEE visualization 2001. San Diego, pp 477–80Google Scholar
- 16.Kanitsar A, Wegenkittl R, Felkel P, Sandner D, Groeller E, Fleischmann D (2001) Automated vessel detection at lower extremity multislice CTA. Eur Radiol 11(S1):236Google Scholar