European Radiology

, Volume 17, Issue 12, pp 3100–3102 | Cite as

Ultrasound-guided breast biopsy using a 10-gauge self-contained vacuum-assisted device

  • Tibor Vag
  • Stefan O. R. Pfleiderer
  • Joachim Böttcher
  • Susanne Wurdinger
  • Mieczyslaw Gajda
  • Oumar Camara
  • Werner A. Kaiser


The purpose of this study was to evaluate the diagnostic value of a self-contained battery-driven vacuum-assisted breast biopsy (VABB) system for the sampling of breast masses under ultrasound guidance. Sixty-five patients with 70 lesions underwent percutaneous 10-gauge ultrasound-guided VABB using the coaxial technique. In 38 lesions, subsequent surgery and comparison of histology was performed. The remaining 32 cases were followed-up and defined as true negative after a cancer-free interval of 24 months. VABB revealed malignant histology in 28 (40%) cases. Twenty-four malignancies were confirmed after surgery. Four invasive cancers verified in VABB were not found during surgery because they were completely removed, as proved by a disease-free interval of 24 months. One cancer missed in ultrasound-guided VABB due to its small size was successfully diagnosed with stereotactic VABB and thus turned out to be false negative, resulting in an overall sensitivity of 96.6%. Forty-one patients were free of cancer during the follow-up period of at least 24 months. In conclusion, the self-contained VABB device is well suited for ultrasound-guided breast biopsies.


Breast biopsy Ultrasound guided Vacuum-assisted device Breast cancer 


  1. 1.
    Parker SH, Jobe WE, Dennis MA, Stavros AT, Johnson KK, Yakes WF, Truell JE, Price JG, Kortz AB, Clark DG (1993) US-guided automated large-core breast biopsy. Radiology 187:507–511PubMedGoogle Scholar
  2. 2.
    O’Higgins N, Linos DA, Blicher-Toft M et al (1998) European guidelines for quality assurance in the surgical management of mammographically detected lesions. European Breast Cancer Working Group. Ann Chir Gynaecol 87:110–112PubMedGoogle Scholar
  3. 3.
    Sittek H, Kessler M, Reiser M (2004) Minimally invasive biopsy and preoperative marking of suspect mammary lesions. Gynäkol Geburtshilf Rundsch 44:69–83CrossRefGoogle Scholar
  4. 4.
    Helbich TH, Matzek W, Fuchsjäger MH (2004) Stereotactic and ultrasound-guided breast biopsy. Eur Radiol 14:383–393PubMedCrossRefGoogle Scholar
  5. 5.
    Memarsadeghi M, Pfarl G, Riedl C, Wagner T, Rudas M, Helbich TH (2003) Value of 14-gauge ultrasound-guided large-core needle biopsy of breast lesions: own results in comparison with the literature. Röfo 175:374–380PubMedGoogle Scholar
  6. 6.
    Sittek H, Wieser A, Kessler M, Britsch S, Vick C, Untch M, Reiser M (2005) Sonographically guided, minimally invasive biopsy of uncertain mammary lesions. Clinical experience with a new biopsy system. Radiologe 45:269–277PubMedCrossRefGoogle Scholar
  7. 7.
    Philpotts LE, Hooley RJ, Lee CH (2003) Comparison of automated versus vacuum-assisted biopsy methods for sonographically guided core biopsy of the breast. AJR Am J Roentgenol 180:347–351PubMedGoogle Scholar
  8. 8.
    Wallis M, Tarvidon A, Helbich T, Schreer I (2007) Guidelines from the European Society of Breast Imaging for diagnostic interventional breast procedures. Eur Radiol 17:581–588PubMedCrossRefGoogle Scholar
  9. 9.
    Lopez-Medina A, Cintora E, Mugica B, Opere E, Vela A, Ibanez T (2006) Radial scars diagnosed at stereotectic core needle biopsy: surgical biopsy findings. Eur Radiol 16:1803–1810PubMedCrossRefGoogle Scholar
  10. 10.
    The National Cancer Insitute: http://www.
  11. 11.
    The American Cancer Society: http://www.
  12. 12.
    The US Preventive Services Task Force:
  13. 13.
    Liberman L (2000) Percutaneous imaging-guided core breast biopsy: state of the art at the millenium. AJR Am J Roentgenol 174:1191–1199PubMedGoogle Scholar
  14. 14.
    Simon JR, Kalbhen CL, Flisak ME (2000) Accuracy and complication rate of US guided vacuum-assisted core breast biopsy: initial results. Radiology 215:694–697PubMedGoogle Scholar
  15. 15.
    Parker SH, Klaus AJ, McWey PJ, Schilling KJ, Cupples TE, Duchesne N, Guenin MA, Harness JK (2001) Sonographically guided directional vacuum-assisted breast biopsy using a handheld device. AJR Am J Roentgenol 177:405–408PubMedGoogle Scholar
  16. 16.
    Schulz-Wendtland R, Krämer S, Bautz W (2003) First experiences with a new vacuum assisted device for breast biopsy. Röfo 175:1564–1566PubMedGoogle Scholar
  17. 17.
    Schulz-Wendtland R, Wenkel E, Imhof K, Bani N, Bock K, Degenhardt F, Bautz W (2005) Interventional methods in diagnostics of the breast—a new vacuum biopsy system for the breast in routine clinical practice. Ultraschall Med 26:411–414PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Tibor Vag
    • 1
  • Stefan O. R. Pfleiderer
    • 1
  • Joachim Böttcher
    • 1
  • Susanne Wurdinger
    • 1
  • Mieczyslaw Gajda
    • 2
  • Oumar Camara
    • 3
  • Werner A. Kaiser
    • 1
  1. 1.Institute of Diagnostic and Interventional RadiologyFriedrich Schiller University Hospital JenaJenaGermany
  2. 2.Institute of PathologyFriedrich Schiller University Hospital JenaJenaGermany
  3. 3.Clinic of GynecologyFriedrich Schiller University Hospital JenaJenaGermany

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