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European Radiology

, Volume 17, Issue 10, pp 2589–2597 | Cite as

Detecting endoleaks after endovascular AAA repair with a minimally invasive, implantable, telemetric pressure sensor: an in vitro study

  • Fabian SpringerEmail author
  • Roland Schlierf
  • Joachim-Georg Pfeffer
  • Andreas H. Mahnken
  • Uwe Schnakenberg
  • Thomas Schmitz-Rode
Experimental

Abstract

A feasibility study on a completely digital telemetric pressure sensor (TPS) to detect endoleaks was performed in an in vitro model of an abdominal aortic aneurysm (AAA). An endovascular-stented AAA silicone model with different types (I–III) and sizes (3–11 French) of endoleaks was created and pulsatile pressure was applied with physiological flow and pressure rates [mean intraaortic pressure (IAP): 95–130 mmHg] and different degrees of thrombosis of the aneurysm sac. Aneurysm sac pressure (ASP) was measured with the TPS and with wired pressure sensors (WPS) as a reference. Statistical analysis included paired t-test, Pearson’s correlation analysis and Bland-Altman plots. After opening an endoleak, the mean ASP increased significantly (P < 0.0001) from 15 to almost 95% of the mean IAP depending on endoleak type and size. ASP could be measured accurately with the TPS and the WPS. The telemetric and wired ASP increase showed a high Pearson’s correlation coefficient (r) for a non-thrombosed (r = 0.97) and a thrombosed (r = 0.96) aneurysm sac. In an in vitro silicone model, the newly designed telemetric pressure sensor was able to detect the occurrence of an endoleak in a non-invasive way and might be a valuable device for follow-up of endovascular AAA repair.

Keywords

Aortic aneurysm Endovascular repair Endoleak Pressure sensor 

Abbreviations

AAA

abdominal aortic aneurysm

EVAR

endovascular abdominal aortic aneurysm repair

TPS

telemetric pressure sensor

WPS

wired pressure sensor

IAP

intraaortic pressure

ASP

aneurysm sac pressure

Notes

Acknowledgements

The project was funded by the RWTH Aachen University (Grant Innovationsfond “AAA Leakage Detector”) and the German Federal Ministry of Education and Research (Grant IMEX). Furthermore thanks to Jan Tomko for technical support concerning different pressure-measurement devices.

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Fabian Springer
    • 1
    Email author
  • Roland Schlierf
    • 2
  • Joachim-Georg Pfeffer
    • 1
  • Andreas H. Mahnken
    • 1
    • 3
  • Uwe Schnakenberg
    • 2
  • Thomas Schmitz-Rode
    • 1
  1. 1.Helmholtz-Institute for Biomedical Engineering, Applied Medical EngineeringRWTH Aachen UniversityAachenGermany
  2. 2.Institute of Materials in Electrical Engineering IRWTH Aachen UniversityAachenGermany
  3. 3.Department of Diagnostic Radiology, University HospitalRWTH Aachen UniversityAachenGermany

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