European Radiology

, Volume 16, Issue 12, pp 2828–2833

Potential role of Calogen as an oral contrast medium in the evaluation of the gastric wall at MRI

  • Derek G. Lohan
  • Sinead M. Walsh
  • Ruaridh H. Allen
  • Carmel G. Cronin
  • Conor P. Meehan
  • Joseph M. Murphy
  • Peter A. McCarthy
Gastrointestinal

Abstract

Evaluation of gastric wall pathology using cross-sectional imaging has proved difficult, particularly in the imaging of early, localized disease. The properties of Calogen as a negative oral contrast agent for the evaluation of the upper gastro-intestinal tract and retroperitoneum in CT has been well described. We assess the suitability of this agent as an oral contrast medium for use in MRI examination of the gastric wall, finding the mean scores for Calogen and water with regard to gastric distension to be 8.46 and 5.49, respectively (P<0.01). Concerning obliteration of mucosal detail, the respective scores are 8.48 and 3.84 (P<0.01). Calogen is also statistically superior to water with regard to prevention of peristalsis and homogeneity (mean scores 8.15 vs. 5.74 and 8.69 vs. 6.30, respectively). Oral Calogen, therefore, is superior to water as an oral contrast agent for MRI examination of the gastric wall. Its ingestion allows identification of the gastric wall with fat intensity material on both sides, further aiding characterisation of subtle mural anomalies.

Keywords

Fat contrast Gastric wall MRI 

References

  1. 1.
    Pickhardt et al (2003) Wall thickening of the gastric antrum as a normal finding: multidetector CT with cadaveric comparison. AJR 181:973–979PubMedGoogle Scholar
  2. 2.
    Insko et al (2003) Benign and malignant lesions of the stomach: evaluation of CT criteria for differentiation. Radiology 228(1):166–171PubMedGoogle Scholar
  3. 3.
    Ramsay DW, Markham DH, Morgan B, Rodgers PM, Liddicoat AJ (2001) The use of dilute Calogen as a fat density oral contrast medium in upper abdominal computed tomography, compared with the use of water and positive oral contrast media. Clin Radiol 56(8):670–673, AugPubMedCrossRefGoogle Scholar
  4. 4.
    Balwin GN (1978) Computer tomography of the pancreas: negative contrast medium. Radiology 128:827–828Google Scholar
  5. 5.
    Sato C, Naganawa S, Kumada H, Miura S, Ishigaki T (2004) MR imaging of gastric cancer in vitro: accuracy of invasion depth diagnosis. Eur Radiol 14:1543–1549PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Derek G. Lohan
    • 1
  • Sinead M. Walsh
    • 1
  • Ruaridh H. Allen
    • 1
  • Carmel G. Cronin
    • 1
  • Conor P. Meehan
    • 1
  • Joseph M. Murphy
    • 1
  • Peter A. McCarthy
    • 1
  1. 1.Department of RadiologyUniversity College HospitalGalwayIreland

Personalised recommendations