European Radiology

, Volume 15, Issue 4, pp 727–741 | Cite as

Imaging of macrophage-related lung diseases

  • Katharina Marten
  • David M. HansellEmail author


Macrophage-related pulmonary diseases are a heterogeneous group of disorders characterized by macrophage accumulation, activation or dysfunction. These conditions include smoking-related interstitial lung diseases, metabolic disorders such as Niemann–Pick or Gaucher disease, and rare primary lung tumors. High-resolution computed tomography abnormalities include pulmonary ground-glass opacification secondary to infiltration by macrophages, centrilobular nodules or interlobular septal thickening reflecting peribronchiolar or septal macrophage accumulation, respectively, emphysema caused by macrophage dysfunction, and honeycombing following macrophage-related lung matrix remodeling.


Computed tomography Smoking Lung Lung neoplasms 


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of RadiologyRoyal Brompton HospitalLondonUK

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