European Radiology

, Volume 15, Issue 2, pp 312–318 | Cite as

Assessment of right ventricular function by 16-detector-row CT: comparison with magnetic resonance imaging

  • K. Koch
  • F. Oellig
  • K. Oberholzer
  • P. Bender
  • P. Kunz
  • P. Mildenberger
  • U. Hake
  • K.-F. Kreitner
  • M. Thelen


The purpose of this study was to determine right ventricular (RV) function from 16-detector-row CT by using two different software tools in comparison with MRI. Nineteen patients underwent cardiac CT. (1) With semiautomated contour detection software end-diastolic and end-systolic RV volumes were determined from short-axis CT reformations (MPR) created at every 10% of the RR-interval. (2) End-systolic and end-diastolic axial images were transformed to 3D to determine the volumes by using a threshold-supported reconstruction algorithm. Steady-state free-precession cine-MRI of the heart was done in short-axis orientation. RV function could not be analyzed in one patient because of sternal wire artifacts in MRI. Mean end-diastolic (155.4±54.6 ml) and end-systolic (79.1±37.0 ml) RV volumes determined with MPR correlated well with MRI [151.9±53.7 ml (r=0.98) and 75.0±36.0 ml (r=0.96), respectively (P<0.001)]. RV stroke volume (76.2±20.2 ml for MPR-CT, 76.9±20.7 ml for MRI, r=0.93) showed a good correlation and RV ejection fraction (50.8±8.4% for MPR-CT, 51.9±7.4% for MRI, r=0.74) only a moderate one. Threshold supported 3D reconstructions revealed insufficient correlations with MRI (r=0.31–0.59). MPR-based semiautomated analysis of cardiac 16 detector-row CT allows for RV functional analysis. The results correlate well with MRI findings. Threshold value-supported 3D reconstructions did not show satisfying results because of inhomogeneities of RV contrast enhancement.


Heart CT Multidetector-row Function Ventricles MRI 


  1. 1.
    Blobel J, Baartman H, Rogalla P, Mews J, Lembcke A (2003) Spatial and temporal resolution with 16-slice computed tomography for cardiac imaging. Fortschr Röntgenstr 175:1264–1271Google Scholar
  2. 2.
    Juergens KU, Grude M, Maintz D, Fallenberg EM, Wicher T, Heindel W, Fischbach R (2004) Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience. Radiology 230:403–410PubMedGoogle Scholar
  3. 3.
    Grude M, Juergens KU, Wichter T, Paul M, Fallenberg EM, Muller JG, Heindel W, Breithardt G, Fischbach R (2003) Evaluation of global left ventricular myocardial function with elelctrocardiogram-gated multidetector computed tomography. Comparison with magnetic resonance imaging. Invest Radiol 38:653–661PubMedGoogle Scholar
  4. 4.
    Ehrhard K, Oberholzer K, Gast K, Mildenberger P, Kreitner KF, Thelen M (2002) Mehrschicht-CT des Herzens. Schwellenwertgestützte 3D-Volumetrie zur Bestimmung der linksventrikulären Pumpfunktion im Vergleich zur Magnetresonanztomographie. Fortschr Röntgenstr 174:1566–1569CrossRefGoogle Scholar
  5. 5.
    Heuschmid M, Kuttner A, Schroder S, Trebar B, Burgstahler C, Mahnken A, Niethammer M, Trabold T, Kopp AF, Claussen CD (2003) Bestimmung der linksventrikulären Funktionsparameter mittels EKG-gesteuerter Mehrschicht-Computertomographie im Vergleich mit der invasiven Ventrikulographie. Fortschr Röntgenstr 175:1349–1354Google Scholar
  6. 6.
    Mahnken AH, Spüntrup E, Wildberger JE, Heuschmid M, Niethammer M, Sinha AM, Flohr T, Bücker A, Günther RW (2003) Quantifizierung der Herzfunktion in der Mehrschicht-Spiral-CT mit retrospektivem EKG-Gating: Vergleich zur Kernspintomographie. Fortschr Röntgenstr 175:83–88Google Scholar
  7. 7.
    Boehm T, Alkadhi H, Roffi M, Willmann JK, Desbiolles LM, Marincek B, Wildermuth S (2004) Time-effectiveness, observer-dependence, and accuracy of measurements of left ventricular ejection fraction using 4-channel MDCT. Fortschr Röntgenstr 176:529–537Google Scholar
  8. 8.
    Kim T, Kim S, Ryu Y, Kim Y, Kim H (2004) Evaluation of multidetector-row CT (MDCT) coronary angiography for determination of right ventricular function and comparison with first-pass radionuclide angiography. Eur Radiol 14(Supplement 2):S270Google Scholar
  9. 9.
    Dorgelo J, van Ooijen PMA, Oudkerk M (2003) Imaging coronary artery bypass grafts using 16-slice multidetector computed tomography. Imaging Decis 7(2):9–14CrossRefGoogle Scholar
  10. 10.
    Marano R, Storto ML, Maddestra N, Bonomo L (2004) Non-invasive assessment of coronary artery bypass graft with retrospectively ECG-gated four-row multi-detector spiral computed tomography. Eur Radiol. DOI 10.1007/s00330-004-2323-3, published online 22 April 2004Google Scholar
  11. 11.
    Stamm G, Nagel HD (2002) CT-expo—a novel program for dose evaluation in CT. Fortschr Roentgenstr 174:1570–1576CrossRefGoogle Scholar
  12. 12.
    Manzke R, Grass M, Nielsen T, Shechter G, Hawkes D (2003) Adaptive temporal resolution optimization in helical cardiac cone beam CT reconstruction. Med Phys 30(12):3072–3080CrossRefPubMedGoogle Scholar
  13. 13.
    Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1(8476):307–310PubMedGoogle Scholar
  14. 14.
    Flohr T, Bruder H, Stierstorfer K, Simon J, Schaller S, Ohnesorge B (2002) New technical developments in multislice-CT. Part 2. Sub-millimeter 16-slice scanning and increased gantry rotation speed for cardiac imaging. Fortschr Röntgenstr 174:1022–1027CrossRefGoogle Scholar
  15. 15.
    Heuschmid M, Küttner A, Flohr T, Wintersperger JE, Lell M, Kopp AF, Schröder S, Baum U, Schaller S, Hartung A, Ohnesorge B, Claussen CD (2002) Darstellung der Herzkranzgefäße im CT mittels neuer 16-Zeilen-Technologie und reduzierter Rotationszeit. Fortschr Röntgenstr 174:721–724CrossRefGoogle Scholar
  16. 16.
    Miller S, Simonetti OP, Carr J, Kramer U, Finn JP (2002) MR imaging of the heart with cine true fast imaging with steady-state precession: influence of spatial and temporal resolutions on left ventricular functional parameters. Radiology 223:263–269PubMedGoogle Scholar
  17. 17.
    Kreitner K-F, Sandstede J (2004) Computertomographie des Herzens: Aktuelle Leitlinien. Fortschr Roentgenstr 176:632–637Google Scholar
  18. 18.
    Grothues F, Moon JC, Bellenger NG, Smith GS, Klein HU, Pennell DJ (2004) Interstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance. Am Heart J 147:218–223CrossRefPubMedGoogle Scholar
  19. 19.
    Alfakih K, Plein S, Bloomer T, Jones T, Ridgway J, Sivananthan M (2003) Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging. J Magn Reson Imaging 18:25–32CrossRefPubMedGoogle Scholar
  20. 20.
    Becker CR, Knez A, Leber A, Treede H, Ohnesorge B, Schoepf UJ, Reiser MF (2002) Detection of coronary artery stenoses with multislice helical CT angiography. J Comput Assist Tomogr 26:750–755CrossRefPubMedGoogle Scholar
  21. 21.
    Rist C, Becker C, Reiser MF (2003) Change of cardiac output under metoprolol determined by CT indicator dilution method. Eur Radiol 13:H29Google Scholar
  22. 22.
    Dewey M, Borges AC, Kivelitz D, Taupitz M, Wagner S, Baumann G, Hamm B (2004) Coronary artery disease: new insights and their implications for radiology. Eur Radiol 14(6):1048–1054. DOI  10.1007/s00330-003-2175-2CrossRefPubMedGoogle Scholar
  23. 23.
    Ley S, Kauczor HU, Heussel CP, Kramm T, Mayer E, Thelen M, Kreitner KF (2003) Value of contrast-enhanced MR angiography and helical CT angiography in chronic thrombembolic pulmonary hypertension. Eur Radiol 13(10):2365–2371. DOI  10.1007/s00330-003-1878-8CrossRefPubMedGoogle Scholar
  24. 24.
    Coche E, Verschuren F, Hainaut P, Goncette L (2004) Pulmonary embolism findings on chest radiographs and multislice spiral CT. Eur Radiol 14:1241–1248. DOI  10.1007/s00330-003-2203-2CrossRefPubMedGoogle Scholar
  25. 25.
    Collomb D, Paramelle PJ, Calaque O, Bosson JL, Vanzetto G, Barnoud D, Pison C, Coulomb M, Ferretti G (2003) Severity assessment of acute pulmonary embolism: evaluation using helical CT. Eur Radiol 13(7):1508–1514. DOI  10.1007/s00330-002-1804-5CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • K. Koch
    • 1
  • F. Oellig
    • 1
  • K. Oberholzer
    • 1
  • P. Bender
    • 1
  • P. Kunz
    • 1
  • P. Mildenberger
    • 1
  • U. Hake
    • 2
  • K.-F. Kreitner
    • 1
  • M. Thelen
    • 1
  1. 1.Department of RadiologyJohannes Gutenberg-University MainzMainzGermany
  2. 2.Department of Cardiothoracic and Vascular SurgeryJohannes Gutenberg-University MainzMainzGermany

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