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European Radiology

, Volume 15, Issue 3, pp 543–548 | Cite as

Magnetic resonance imaging of pituitary adenomas

  • Jean-François BonnevilleEmail author
  • Fabrice Bonneville
  • Françoise Cattin
Neuro

Abstract

Today, MR is the only method needed for the morphological investigation of endocrine-active pituitary adenomas. In acromegaly and Cushing’s syndrome, the therapeutic attitude is directly dictated by MR data. We present the MR aspect of pituitary adenomas according to size, sex, age, endocrine activity and a few particular conditions such as hemorrhagic pituitary adenomas, pituitary adenomas during pregnancy, cavernous sinus invasion and postsurgical changes. When an intrasellar mass extending out of the sella turcica is detected, the goal of the MR examination is to indicate precisely the origin of the tumor, its extension in relation to the various surrounding structures, its structure and its enhancement in order to help in the differential diagnosis. Demonstration of very small pituitary adenomas remains a challenge. When SE T1- and Turbo SE T2-weighted sequences are non-diagnostic, enhanced imaging becomes mandatory; half-dose gadolinium injection, delayed sequence, dynamic imaging can be of some help.

Keywords

Pituitary gland MR studies Pituitary adenoma 

References

  1. 1.
    Ahmadi J, North CM, Segall HD, Zee CS, Weiss MH (1986) Cavernous sinus invasion by pituitary adenomas. Am J Roentgenol 146:257–262Google Scholar
  2. 2.
    Bonneville JF, Cattin F, Gorczyca W, Hardy J (1993) Pituitary microadenomas: early enhancement with dynamic CT-implications of arterial blood supply and potential importance. Radiology 187:857–861PubMedGoogle Scholar
  3. 3.
    Brismon MH (1996) Symptoms of pituitary apoplexy rapidly reversed with bromocriptine. Case report. J Neurosurg 85:1153–1155PubMedGoogle Scholar
  4. 4.
    Colombo N, Loli P, Vignati F, Scialfa G (1994) MR of corticotropin-secreting pituitary microadenomas. Am J Neuroradiol 15:1591–1595PubMedGoogle Scholar
  5. 5.
    Davis PC, Hoffman JC Jr, Spencer T et al (1987) MR Imaging of pituitary adenoma: CT, clinical and surgical correlation. Am J Roentgenol 148:797–802Google Scholar
  6. 6.
    Davis PC, Hoffman JC Jr, Malko JA et al (1987) Gadolinium-DTPA and MR imaging of pituitary adenoma: a preliminary report. Am J Neuroradiol 8:817–823PubMedGoogle Scholar
  7. 7.
    Davis PC, Gokhale KA, Josep GJ (1991) Pituitary adenoma: correlation of half dose gadolinium enhanced MRI with surgical findings in 26 patients. Radiology 180:779–784PubMedGoogle Scholar
  8. 8.
    Davis PC, Hoffman JC Jr, Spencer T, Tindall GT, Braun IF (1987) MR Imaging of pituitary adenoma: CT, clinical, and surgical correlation. Am J Roentgenol 148:797–802Google Scholar
  9. 9.
    Dietemann JL, Portha C, Cattin F, Mollet E, Bonneville JF (1983) CT Follow-up of microprolactinomas during bromocriptine-induced pregnancy. Neuroradiology 25:133–138CrossRefPubMedGoogle Scholar
  10. 10.
    Doppman JL, Frank JA, Dwyer AJ et al (1988) Gadolinium DTPA enhanced MR imaging of ACTH-secreting microadenomas of the pituitary gland. J Comput Assist Tomogr 12:728–735PubMedGoogle Scholar
  11. 11.
    El Gammal T, Brooks BS (1989) MR imaging of the ectopic bright signal of posterior pituitary regeneration. Am J Neuroradiol 10:323–328PubMedGoogle Scholar
  12. 12.
    Elster AD (1993) Modern imaging of pituitary. Radiology 187:1–14Google Scholar
  13. 13.
    Knosp E, Kitz K, Steiner E, Matula CH (1991) Pituitary adenomas with parasellar invasion. Acta Neurochir 53:65–71Google Scholar
  14. 14.
    Kucharczyk W, Davis DO, Kelly WM, Sze G, Norman D, Newton TH (1986) Pituitary adenomas: high-resolution MR imaging at 1.5 T. Radiology 161:761–765PubMedGoogle Scholar
  15. 15.
    Kucharczyk W, Bishop JE, Plewes DB, Keller MA, George S (1994) Detection of pituitary microadenomas: comparison of dynamic keyhole fast spin-echo, unenhanced, and conventional contrast-enhanced MR imaging. Am J Neuroradiol 15:671–679Google Scholar
  16. 16.
    Lundin P, Bergström K, Nyman R, Lundberg PO, Muhr C (1992) Macroprolactinomas: serial MR imaging in long term bromocriptine therapy. Am J Neuroradiol 13:1279–1291PubMedGoogle Scholar
  17. 17.
    Lundin P (1997) Long-term octreotide therapy in growth hormone-secreting pituitary adenomas: evaluation with serial MR. Am J Neuroradiol 18:765–772PubMedGoogle Scholar
  18. 18.
    Scotti G, Yu CY, Dillon WP et al (1988) MR imaging of cavernous sinus involvement by pituitary adenomas. Am J Neuroradiol 9:657–664Google Scholar
  19. 19.
    Steiner E, Knosp E, Herold CJ et al (1992) Pituitary adenomas: findings of postoperative MR imaging. Radiology 185:521–527PubMedGoogle Scholar
  20. 20.
    Teng MM, Huang C, Chang T (1988) The pituitary mass after transsphenoidal hypophysectomy. Am J Neuroradiol 9:23–26Google Scholar
  21. 21.
    Youssem DM, Arrington JA, Zinreich SJ, Kumar AJ, Bryan RN (1989) Pituitary adenomas: possible role of bromocriptine in intratumoral hemorrhage. Radiology 170:239–243PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Jean-François Bonneville
    • 1
    Email author
  • Fabrice Bonneville
    • 1
  • Françoise Cattin
    • 1
  1. 1.Department of NeuroradiologyUniversity HospitalBesançon CedexFrance

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