European Radiology

, Volume 15, Issue 1, pp 96–101 | Cite as

CT measurement of coronary calcium mass: impact on global cardiac risk assessment

  • Christoph R. Becker
  • Amal Majeed
  • Alexander Crispin
  • Andreas Knez
  • U. Joseph Schoepf
  • Peter Boekstegers
  • Gerhard Steinbeck
  • Maximilian F. Reiser
Cardiac
First Online:
Received:
Revised:
Accepted:

Abstract

Coronary calcium mass percentiles can be derived from electron beam CT as well as from multidetector-row CT of all manufacturers. Coronary calcium mass may serve as a more individualized substitute for age for cardiac risk stratification. The aim was to investigate the potential impact of CT coronary calcium mass quantification on cardiac risk stratification using an adjusted Framingham score. Standardized coronary calcium mass was determined by multidetector-row CT in a total of 1,473 patients (1,038 male, 435 female). The impact on risk stratification of replacing the traditional Framingham age point score by a point score based on calcium mass relative to age was tested. Any coronary calcium found in males in the age group of 20–34 years and females in the age group of 20–59 years results in an increase of the Framingham score by 9 and 4–7 points, respectively. Only in males 65 years of age and older, none or minimal amounts of coronary calcium decrease the Framingham score by three points. The coronary calcium mass and age-related scoring system may have impact on the reassignment of patients with an intermediate Framingham risk to a lower or higher risk group.

Keywords

Coronary calcification Cardiac risk assessment Multidetector-row CT 
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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Christoph R. Becker
    • 1
  • Amal Majeed
    • 1
  • Alexander Crispin
    • 2
  • Andreas Knez
    • 3
  • U. Joseph Schoepf
    • 4
  • Peter Boekstegers
    • 3
  • Gerhard Steinbeck
    • 3
  • Maximilian F. Reiser
    • 1
  1. 1.Department of Clinical RadiologyLudwig-Maximilians-University Hospital MunichMunichGermany
  2. 2.Department of Medical Data Processing, Biometry, and EpidemiologyUniversity Hospital MunichMunichGermany
  3. 3.Department of CardiologyUniversity Hospital MunichMunichGermany
  4. 4.Department of Radiology, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA

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