European Radiology

, Volume 13, Issue 8, pp 2027–2030 | Cite as

Renal venous thrombosis in an infant with predisposing thrombotic factors: color Doppler ultrasound and MR evaluation

  • Maria I. Argyropoulou
  • Vassilios I. Giapros
  • Frederica Papadopoulou
  • Aikaterini A. Drougia
  • Pangiotis Nikolopoulos
  • Georgios A. Vartholomatos
  • Styliani Andronikou


We report a case of a neonate with hereditary thrombophilia presenting with renal venous thrombosis (RVT). Early color Doppler findings of RVT were lacking venous flow, and the arterial diastolic flow was reversed. This very high-resistance arterial flow is for the first time described in neonatal RVT. Magnetic resonance imaging showed low signal intensity of the renal pyramids on T1- and T2-weighted images, suggesting acute hemorrhage. After intravenous contrast injection, persistent cortical enhancement was observed along with lack of medullary enhancement. Despite the progressive reestablishment of some venous drainage, the kidney showed atrophy and loss of function.


Renal vein thrombosis Newborn Color Doppler ultrasound Magnetic resonance imaging Thrombotic factors 


  1. 1.
    Hibbert J, Howlett DC, Greenwood KL, Macdonald LM, Saunders AJS (1997) The ultrasound appearances of neonatal renal vein thrombosis. Br J Radiol 70:1191–1194PubMedGoogle Scholar
  2. 2.
    Wilkinson AG, Murphy AV, Stewart G (2001) Renal venous thrombosis with calcification and preservation of renal function. Pediatr Radiol 31:140–143CrossRefPubMedGoogle Scholar
  3. 3.
    Orazi C, Fariello G, Malena S, Schingo P, Ferro F, Bagolan P (1993) Renal vein throbosis and adrenal hemorrhage in the newborn: ultrasound evaluation of 4 cases. J Clin Ultrasound 21:163–169PubMedGoogle Scholar
  4. 4.
    Heller C, Schobess R, Kurnik K, Junker R, Günther G, Kreuz W, Nowak-Göttl U (2000) Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors a multicentre case control study Br J Haematol 111:534–539CrossRefGoogle Scholar
  5. 5.
    Nowak-Göttl U, von Kries R, Gobel U (1997) Neonatal symptomatic thromboembolism in Germany: two year survey. Arch Dis Child Fetal Neonatal Ed 76:F163–F167PubMedGoogle Scholar
  6. 6.
    Schobess R, Junker R, Auberger K, Munchow N, Burdach S, Nowak-Göttl U (1999) Factor V G1691A and prothrombin G20210A in childhood spontaneous venous thrombosis evidence of an age-dependent thrombotic onset in carriers of factor V G1691A and prothrombin G20210A mutation. Eur J Pediatr 158: S105–S108PubMedGoogle Scholar
  7. 7.
    Nowak-Göttl U, Junker R, Hartmeier M, Koch HG, Münchow N, Assmann G, von Eckardstein A (1999) Increased lipoprotein (a) is an important factor for venous thromboembolism in childhood. Circulation 100:743–748PubMedGoogle Scholar
  8. 8.
    Cremin BJ, Davey H, Oleszczuk-Raszke K (1991) Neonatal renal venous thrombosis: sequential ultrasonic appearances. Clin Radiol 44:52–55PubMedGoogle Scholar
  9. 9.
    Laplante S, Patriquin HB, Robitaille P, Filiatrault D, Grignon A, Decarie JC (1993) Renal vein thrombosis in children: evidence of early flow recovery with Doppler US. Radiology 189:37–42PubMedGoogle Scholar
  10. 10.
    Metreweli C, Pearson R (1984) Echographic diagnosis of neonatal renal venous thrombosis. Pediatr Radiol 14:105–108PubMedGoogle Scholar
  11. 11.
    Brill PW, Jagannath A, Winchester P, Markisz JA, Zirinsky K (1989) Adrenal hemorrhage and renal vein thrombosis in the newborn: MR imaging. Radiology 170:95–98PubMedGoogle Scholar
  12. 12.
    Kaveggia LP, Perrella RR, Grant EG, Tessler FN, Rosenthal JT, Wilkinson A, Danovitch GM (1990) Duplex Doppler sonography in renal allografts: the significance of reversed flow in diastole. AJR 155:295–298Google Scholar
  13. 13.
    Reuther G, Wanjura D, Bauer H (1989) Acute renal vein thrombosis in renal allografts: detection with duplex Doppler US. Radiology 170:557–558PubMedGoogle Scholar
  14. 14.
    Mattle HP, Edelman RR, Schroth G, O'Reilly GV (1996) Spontaneous and traumatic hemorrhage. In: Edelman RR, Hesselink JR, Zlatkin MB (eds) Clinical magnetic resonance imaging. Saunders, Philadelphia, pp 652–702Google Scholar
  15. 15.
    Sari A, Ozyavuz R, Demirci A, Ercin C, Arslan A, Yuzuncu AK, Gumele HR (1999) MR imaging of renal vein occlusion in dogs. Invest Radiol 34:523–529CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Maria I. Argyropoulou
    • 1
  • Vassilios I. Giapros
    • 2
  • Frederica Papadopoulou
    • 1
  • Aikaterini A. Drougia
    • 2
  • Pangiotis Nikolopoulos
    • 1
  • Georgios A. Vartholomatos
    • 3
  • Styliani Andronikou
    • 2
  1. 1.Department of RadiologyMedical School, University of IoanninaIoanninaGreece
  2. 2.Neonatology ClinicMedical School, University of IoanninaIoanninaGreece
  3. 3.Department of HaematologyMedical School, University of IoanninaIoanninaGreece

Personalised recommendations