Plant Cell Reports

, Volume 31, Issue 7, pp 1227–1232 | Cite as

Exogenous thermospermine has an activity to induce a subset of the defense genes and restrict cucumber mosaic virus multiplication in Arabidopsis thaliana

  • G. H. M. Sagor
  • Hideki Takahashi
  • Masaru Niitsu
  • Yoshihiro Takahashi
  • Thomas Berberich
  • Tomonobu Kusano
Original Paper

Abstract

We previously proposed the defensive role of a signal pathway triggered by the polyamine spermine (Spm) in the reaction against avirulent viral pathogens in Nicotiana tabacum and Arabidopsis thaliana. In this study, we showed that thermospermine (T-Spm), an isomer of Spm, is also active in inducing the expression of the genes involved in the Spm-signal pathway at a similar dose as Spm. Furthermore, we found that T-Spm enhances the expression of a subset of pathogenesis-related genes whose expression is induced during cucumber mosaic virus (CMV)-triggered hypersensitive response. In consistent with the above observation, we further showed that exogenous T-Spm can repress CMV multiplication with same efficiency as Spm.

Key message

Polyamine thermospermine, an isomer of spermine, is able to induce a subset of hypersensitive response-related defense genes and can suppress cucumber mosaic virus multiplication in Arabidopsis thaliana.

Keywords

Arabidopsis thaliana Cucumber mosaic virus Polyamine Signaling activity Spermine Thermospermine 

Notes

Acknowledgments

This work was supported in part by Grant-in-Aids from the Japan Society for the Promotion of Science (JSPS) to TK (21380063) and YT (21780087), and by the grant from The Saito Gratitude Foundation (to GHMS) and by the research funding programme “LOEWE-Landes-Offensive zur Entwicklung Wissenschaftlich-ökonomischer Exzellenz” of Hesse’s Ministry of Higher Education, Research, and the Arts (to TB). GHMS is a recipient of MEXT scholarship.

Supplementary material

299_2012_1243_MOESM1_ESM.doc (38 kb)
Supplementary material 1 (DOC 37 kb)

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • G. H. M. Sagor
    • 1
  • Hideki Takahashi
    • 2
  • Masaru Niitsu
    • 3
  • Yoshihiro Takahashi
    • 1
  • Thomas Berberich
    • 4
  • Tomonobu Kusano
    • 1
  1. 1.Graduate School of Life SciencesTohoku UniversitySendaiJapan
  2. 2.Graduate School of Agricultural SciencesTohoku UniversitySendaiJapan
  3. 3.Faculty of Pharmaceutical SciencesJosai UniversitySakadoJapan
  4. 4.Biodiversity and Climate Research Center (BiK-F), BioCampus-WestendFrankfurt am MainGermany

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