Rheumatology International

, Volume 40, Issue 2, pp 313–321 | Cite as

Profile of new referrals to a single pediatric rheumatology center in Turkey

  • Şerife Gül Karadağ
  • Hafize Emine Sönmez
  • Ayşe Tanatar
  • Figen Çakmak
  • Mustafa Çakan
  • Nuray Aktay AyazEmail author
Observational Research


To describe the demographic characteristics and clinical features of patients referred to a pediatric rheumatology outpatient clinic in Turkey and to compare the final diagnoses with the previous literature data. All new patients referred to pediatric rheumatology outpatient clinic of Kanuni Sultan Süleyman Research and Training Hospital between March 2018 and March 2019 were enrolled to the study. Demographic data, referral patterns, disease related features, physical examination findings and final diagnoses of new referrals were collected prospectively. A total of 2982 new referrals were evaluated in 1-year period. Among them 1561 (52%) had a diagnosis of a rheumatic disease. The frequencies of most common rheumatic diseases were; periodic fever syndromes (47.3%), juvenile idiopathic arthritis (18%) and vasculitis (14.4%), respectively. Non-rheumatic conditions were diagnosed in 1243 patients, among them orthopedic/mechanic problems (27.4%) were the most frequent ones followed by vitamin D deficiency (17.5%) and dermatological problems (9.8%). Patients with non-rheumatic conditions comprised a large part of the pediatric rheumatology outpatient clinic. National registries are required to establish the frequencies of pediatric rheumatic diseases in Turkey.


Juvenile idiopathic arthritis Pediatric rheumatology Periodic fever syndromes Rheumatic diseases 


Author contributions

ŞGK conceptualized and designed the study, drafted the initial manuscript, and had full access to all the data in the study; HES designed the study, conducted the data analyses, drafted the initial manuscript, and had full access to all the data in the study; AT, FÇ and MÇ drafted the initial manuscript; NAA conceptualized and designed the study, drafted the final manuscript, and had full access to all the data in the study and all authors reviewed and revised the manuscript and approved the final manuscript as submitted and agree to be accountable for all aspects of the work.



Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interest.

Informed consent

All participants and parents provided written informed consent.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Rheumatology, Department of Pediatrics, Kanuni Sultan Süleyman Research and Training HospitalUniversity of Health ScienceKucukcekmeceTurkey

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