Rheumatology International

, Volume 32, Issue 11, pp 3331–3338

Infection and autoimmune disease

Review Article

DOI: 10.1007/s00296-012-2451-z

Cite this article as:
Sener, A.G. & Afsar, I. Rheumatol Int (2012) 32: 3331. doi:10.1007/s00296-012-2451-z


Most infectious agents, such as viruses, bacteria and parasites, can trigger autoimmunity via different mechanisms. The development of an autoimmune disorder after infection tends to occur in genetically susceptible individuals. Some parameters, such as genetic predisposition, feature of the infectious agent and sometimes protective effect of the infections, have a significant role in this process. These parameters and various pathogens that could lead to enhancement or exacerbation of autoimmune disease were examined in this review. Recent studies were reviewed from a microbiological perspective.


Infection Autoimmune disease 

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Microbiology and Clinical Microbiology DepartmentAtaturk Training and Research HospitalIzmirTurkey

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